Low cytotoxicity of ecteinascidin 743 in yeast lacking the major endonucleolytic enzymes of base and nucleotide excision repair pathways

Biochemical Pharmacology

Volumn 70, Issue 1, 2005, Pages 59-69

  Soares, Daniele Grazziotin ^a,b   Poletto, Nadine Paese ^a   Bonatto, Diego ^b   Salvador, Mirian ^a   Schwartsmann, Gilberto ^c   Pêgas Henriques, João Antonio ^a,b,d  

^a UNIVERSITY OF CAXIAS DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Apn1p; Base excision repair; ET 743; Nucleotide excision repair; Rad1p; Saccharomyces cerevisiae

Indexed keywords

ENDONUCLEASE; TRABECTEDIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DIPLOIDY; DNA SYNTHESIS; DRUG MECHANISM; DRUG SENSITIVITY; EXCISION REPAIR; GENE CONVERSION; HAPLOIDY; HOMOLOGOUS RECOMBINATION; MITOSIS; MITOTIC RECOMBINATION; MUTAGENESIS; MUTAGENIC ACTIVITY; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SACCHAROMYCES CEREVISIAE; SOMATIC CROSSING OVER; STRAIN DIFFERENCE;

ANTINEOPLASTIC AGENTS; DIOXOLES; DNA DAMAGE; DNA REPAIR; ISOQUINOLINES; MITOSIS; MUTATION; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; TETRAHYDROISOQUINOLINES;

EID: 20444426538     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.04.013     Document Type: Article

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