Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae

Genetics

Volumn 164, Issue 2, 2003, Pages 443-455

  Morey, Natalie J ^a,b,c   Doetsch, Paul W ^a,b   Jinks Robertson, Sue ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c NATL CENTER FOR INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CELL DIVISION; CELL SURVIVAL; DIPLOIDY; DNA DAMAGE; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; EXCISION REPAIR; FUNGAL GENE; FUNGUS GROWTH; GENE INACTIVATION; GENE MUTATION; GENETIC PREDISPOSITION; GENETICS; GENOME; GENOTYPE; HAPLOIDY; HOMOZYGOTE; METABOLISM; MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ALLELES; CELL DIVISION; CELL SURVIVAL; DIPLOIDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENES, FUNGAL; GENETIC PREDISPOSITION TO DISEASE; GENOME, FUNGAL; GENOTYPE; HAPLOIDY; HOMOZYGOTE; MUTATION; PLASMIDS; SACCHAROMYCES CEREVISIAE;

FUNGI; MYXOGASTRIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; ZIZIPHUS MAURITIANA;

EID: 0038801552     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (80)

1. ARMAN, I. P., and T. A. DUTOVA, 1975 Ploidy and liquid-holding recovery in yeasts sensitive to radiation and nitrous acid. Genetika 11: 80-89.
2. ASAD, L. M., D. C. MEDEIROS, I. FELZENSZWALB, A. C. LEITAO and N. R. ASAD, 2000 Participation of stress-inducible systems and enzymes involved in BER and NER in the protection of Escherichia coli against cumene hydroperoxide. Mutat. Res. 461: 31-40.
3. ASTROM, S. U., S. M. OKAMURA and J. RINE, 1999 Yeast cell-type regulation of DNA repair. Nature 397: 310.
4. BARTON, A. B., and D. B. KABACK, 1994 Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUA38-MAK16-SPO7 region. J. Bacteriol. 176: 1872-1880.
5. BEAM, C. A., R. K. MORTIMER, R. C. WOLFE and C. A. TOBIAS, 1954 The relation of radioresistance to building in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 49: 110-122.
6. BENNETT, R. A., 1999 The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis. Mol. Cell. Biol. 19: 1800-1809.
7. BOEKE, J. D., J. TRUEHEART, G. NATSOULIS and G. R. FINK, 1987 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154: 164-175.
8. BROOMFIELD, S., T. HRYCIW and W. XIAO, 2001 DNA postreplication repair and mutagenesis in Saccharomyes cerevisiae. Mutat. Res. 486: 167-184.
9. CEJKA, P., V. VONDREJS and Z. STORCHOVÁ, 2001 Dissection of the functions of the Saccharomyces cerevisiae RAD6 postreplicative repair group in mutagenesis and UV sensitivity. Genetics 159: 953-963.
10. CHANET, R., D. H. WILLIAMSON and E. MOUSTACCHI, 1973 Cyclic variations in killing and "petite" mutagenesis induced by ultraviolet light in synchronized yeast strains. Biochim. Biophys. Acta 324: 290-299.
11. CLEVER, B., J. SCHMUCKLI-MAURER, M. SIGRIST, B.J. GLASSNER and W. D. HEYER, 1999 Specific negative effects resulting from elevated levels of the recombinational repair protein Rad54p in Saccharomyces cerevisiae. Yeast 15: 721-740.
12. COX, B., and J. GAME, 1974 Repair systems in Saccharomyces. Mutat. Res. 26: 257-264.
13. CROMIE, G. A., J. C. CONNELLY and D. R. LEACH, 2001 Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans. Mol. Cell 8: 1163-1174.
14. DATTA, A., J. L. SCHMEITS, N. S. AMIN, P. J. LAU, K. MYUNG et al., 2000 Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Mol. Cell 6: 593-603.
15. DAVIDOW, L. S., and B. BYERS, 1984 Enhanced gene conversion and postmeiotic segregation in pachytene-arrested Saccharomyces cerevisiae. Genetics 106: 165-183.
16. DIANOV, G. L., N. SOUZA-PINTO, S. G. NYAGA, T. THYBO, T. STEVNSNER et al., 2001 Base excision repair in nuclear and mitochondrial DNA. Prog. Nucleic Acid Res. Mol. Biol. 68: 285-297.
17. DOWLING, E. L., D. H. MALONEY and S. FOGEL, 1985 Meiotic recombination and sporulation in repair-deficient strains of yeast. Genetics 109: 283-302.
18. FALCO, S. C., and K. S. DUMAS, 1985 Genetic analysis of mutants of Saccharomyces cerevisiae resistant to the herbicide sulfometuron methyl. Genetics 109: 21-35.
19. FALCO, S. C., K. S. DUMAS and K. J. LIVAK, 1985 Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase. Nucleic Acids Res. 13: 4011-4027.
20. GAME, J. C., 1993 DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces. Semin. Cancer Biol. 4: 73-83.
21. GAME, J. C., 2000 The Saccharomyces repair genes at the end of the century. Mutat. Res. 451: 277-293.
22. GELLON, L., R. BARBEY, P. AUFFRET VAN DER KEMP, D. THOMAS and S. BOITEUX, 2001 Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae. Mol. Genet. Genomics 265: 1087-1096.
23. GIETZ, R. D., R. H. SCHIESTL, A. R. WILLEMS and R. A. WOODS, 1995 Studies on the transformation of intact yeast cells by the LiAc/ SS-DNA/PEG procedure. Yeast 11: 355-360.
24. GOLDSTEIN, A. L., and J. H. McCUSKER, 1999 Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15: 1541-1553.
25. GREENE, C. N., and S. JINKS-ROBERTSON, 1997 Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. Mol. Cell. Biol. 17: 2844-2850.
26. GROSSMANN, K. F., A. M. WARD, M. E. MATKOVIC, A. E. FOLIAS and R. E. MOSES, 2001 S. cerevisiae has three pathways for DNA interstrand crosslink repair. Mutat. Res. 487: 73-83.
27. HARACSKA, L., I. UNK, R. E. JOHNSON, E. JOHANSSON, P. M. BURGERS et al., 2001 Roles of yeast DNA polymerases δ and ζ and of Rev1 in the bypass of abasic sites. Genes Dev. 15: 945-954.
28. HENRIQUES, J. A., and E. MOUSTACCHI, 1981 Interactions between mutations for sensitivity to psoralen photoaddition (pso) and to radiation (rad) in Saccharomyces cerevisiae. J. Bacteriol. 148: 248-256.
29. HEUDE, M., and F. FABRE, 1993 a/α-control of DNA repair in the yeast Saccharomyces cerevisiae: genetic and physiological aspects. Genetics 133: 489-498.
30. HUANC, J. C., D. S. HSU, A. KAZANTSEV and A. SANCAR, 1994 Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc. Natl. Acad. Sci. USA 91: 12213-12217.
31. KAYTOR, M. D., and D. M. LIVINGSTON, 1994 Saccharomyces cerevisiae rad52 alleles temperature-sensitive for the repair of DNA double-strand breaks. Genetics 137: 933-944.
32. KAYTOR, M. D., and D. M. LIVINGSTON, 1996 Alele-specific suppression of temperature-sensitive mutations of the Saccharomyces cerevisiae RAD52 gene. Curr. Genet. 29: 203-210.
33. KLEIN, H. L., 2001 Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Δ with other DNA repair genes in Saccharomyces cerevisiae. Genetics 157: 557-565.
34. KUIPERS, G. K., B. J. SLOTMAN, H. A. POLDERVAART, I. M. VAN VILSTEREN, C. A. REITSMA-WIJKER et al., 2000 The role of nucleotide excision repair of Escherichia coli in repair of spontaneous and γ-radiation-induced DNA damage in the lacZα gene. Mutat. Res. 460: 117-125.
35. KUZMINOV, A., 2001 DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination. Proc. Natl. Acad. Sci. USA 98: 8461-8468.
36. LAWRENCE, C., 1994 The RAD6 DNA repair pathway in Saccharomyces cerevisiae: What does it do, and how does it do it? Bioessays 16: 253-258.
37. LAWRENCE, C. W., and R. CHRISTENSEN, 1976 UV mutagenesis in radiation-sensitive strains of yeast. Genetics 82: 207-232.
38. LEA, D. E., and C. A. COULSON, 1948 The distribution of the numbers of mutants in bacterial populations. J. Genet. 49: 264-284.
39. MARTI, T. M., C. KUNZ and O. FLECK, 2002 DNA mismatch repair and mutation avoidance pathways. J. Cell. Physiol. 191: 28-41.
40. MARTIN, P., L. PRAKASH and S. PRAKASH, 1981 a/α-specific effect on the mms3 mutation on ultraviolet mutagenesis in Saccharomyces cerevisiae. J. Bacteriol. 146: 684-691.
41. McKEE, R. H., and C. W. LAWRENCE, 1980 Genetic analysis of γ-ray mutagenesis in yeast. III. Double-mutant strains. Mutat. Res. 70: 37-48.
42. MEMISOGLU, A., and L. SAMSON, 2000a Base excision repair in yeast and mammals. Mutat. Res. 451: 39-51.
43. MEMISOGLU, A., and L. SAMSON, 2000b Contribution of base excision repair, nucleotide excision repair, and DNA recombination to alkylation resistance of the fission yeast Schizosaccharomyces pombe. J. Bacteriol. 182: 2104-2112.
44. MONDON, P., and M. M. SHAHIN, 1992 Comparative studies on the lethal, mutagenic, and recombinogenic effects of ultraviolet-A, -B, -C, and visible light with and without 8-methoxypsoralen in Saccharomyces cerevisiae. Photochem. Photobiol. 55: 713-721.
45. MONTELONE, B. A., M. F. HOEKSTRA and R. E. MALONE, 1988 Spontaneous mitotic recombination in yeast: the hyper-recombinational rem1 mutations are alleles of the RAD3 gene. Genetics 119: 289-301.
46. MOORE, C. W., 1978 Responses of radiation-sensitive mutants of Saccharomyces cerevisiae to lethal effects of bleomycin. Mutat. Res. 51: 165-180.
47. MOREY, N. J., 1999 Genome stability and DNA repair pathways in Saccharomyces cerevisiae. Ph.D. Thesis, Emory University, Atlanta.
48. MORGAN, E. A., N. SHAH and L. S. SYMINGTON, 2002 The requirement for ATP hydrolysis by Saccharomyces cerevisiae Rad51 is bypassed by mating-type heterozygosity or RAD54 in high copy. Mol. Cell. Biol. 22: 6336-6343.
49. MORRISON, A., and A. SUGINO, 1994 The 3′→5′ exonucleases of both DNA polymerases δ and ε participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol. Gen. Genet. 242: 289-296.
50. MORRISON, A., A. L. JOHNSON, L. H. JOHNSTON and A. SUGINO, 1993 Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBO J. 12: 1467-1473.
51. NELSON, J. R., C. W. LAWRENCE and D. C. HINKLE, 1996 Deoxycytidyl transferase activity of yeast Rev1 protein. Nature 382: 729-731.
52. OTTERLEI, M., B. KAVLI, R. STANDAL, C. SKJELBRED, S. BHARATI et al., 2000 Repair of chromosomal abasic sites in vivo involves at least three different repair pathways. EMBO J. 19: 5542-5551.
53. PASTINK, A., J. C. EEKEN and P. H. LOHMAN, 2001 Genomic integrity and the repair of double-strand DNA breaks. Mutat. Res. 480/ 481: 37-50.
54. PRAKASH, L., and D. HIGGINS, 1982 Role of DNA repair in ethyl methanesulfonate-induced mutagenesis in Saccharomyces cerevisiae. Carcinogenesis 3: 439-444.
55. PRAKASH, S., and L. PRAKASH, 2000 Nucleotide excision repair in yeast. Mutat. Res. 451: 13-24.
56. RAMOTAR, D., S. C. POPOFF, E. B. GRALLA and B. DEMPLE, 1991 Cellular role of yeast Apn1 apurinic endonuclease/3′-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol. Cell. Biol. 11: 4537-4544.
57. RAO, B. S., and N. M. REDDY, 1982 Genetic control of budding-cell resistance in the diploid yeast Saccharomyces cerevisiae exposed to γ-radiation. Mutat. Res. 95: 213-224.
58. RUHLAND, A., and M. BRENDEL, 1979 Mutagenesis by cytostatic alkylating agents in yeast strains of differing repair capacities. Genetics 92: 83-97.
59. SAEKI, T., I. MACHIDA and S. NAKAI, 1980 Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae. Mutat. Res. 73: 251-265.
60. SAKOVICH, I. S., and B. D. EFREMOV, 1978 Inactivating effect of N-methyl-N′-nitro-N-nitrosoguanidine on yeasts with different ploidies. Genetika 14: 1834-1837.
61. SANDER, M., and D. RAMOTAR, 1997 Partial purification of Pde1 from Saccharomyces cerevisiae: enzymatic redundancy for the repair of 3′-terminal DNA lesions and abasic sites in yeast. Biochemistry 36: 6100-6106.
62. SAPARBAEV, M., L. PRAKASH and S. PRAKASH, 1996 Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae. Genetics 142: 727-736.
63. SCHILD, D., 1995 Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity. Genetics 140: 115-127.
64. SCOTT, A. D., M. NEISHABURY, D. H. JONES, S. H. REED, S. BOITEUX et al., 1999 Spontaneous mutation, oxidative DNA damage, and the roles of base and nucleotide excision repair in the yeast Saccharomyces cerevisiae. Yeast 15: 205-218.
65. SHERMAN, F., 1991 Getting started with yeast. Methods Enzymol. 194: 3-21.
66. SIEDE, W., and E. C. FRIEDBERG, 1990 Influence of DNA repair deficiencies on the UV sensitivity of yeast cells in different cell cycle stages. Mutat. Res. 245: 287-292.
67. SONG, J. M., B. A. MONTELONE, W. SIEDE and E. C. FRIEDBERG, 1990 Effects of multiple yeast rad3 mutant alleles on UV sensitivity, mutability, and mitotic recombination. J. Bacteriol. 172: 6620-6630.
68. SUNG, P., K. M. TRUJILLO and S. VAN KOMEN, 2000 Recombination factors of Saccharomyces cerevisiae. Mutat. Res. 451: 257-275.
69. SWANSON, R. L., N. J. MOREY, P. W. DOETSCH and S. JINKS-ROSERTSON, 1999 Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. Mol. Cell. Biol. 19: 2929-2935.
70. SYMINGTON, L. S., 1998 Homologous recombination is required for the viability of rad27 mutants. Nucleic Acids Res. 26: 5589-5595.
71. THOMAS, D., A. D. SCOT, R. BARBEY, M. PADULA and S. BOITEUX, 1997 Inactivation of OGG1 increases the incidence of G•C→T•A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells. Mol. Gen. Genet. 254: 171-178.
72. TISHKOFF, D. X., N. FILOSI, G. M. GAIDA and R. D. KOLODNER, 1997 A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 88: 253-263.
73. TORRES-RAMOS, C. A., R. E. JOHNSON, L. PRAKASH and S. PRAKASH, 2000 Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast. Mol. Cell. Biol. 20: 3522-3528.
74. UNK, I., L. HARACSKA, R. E. JOHNSON, S. PRAKASH and L. PRAKASH, 2000 Apurinic endonuclease activity of yeast Apn2 protein. J. Biol. Chem. 275: 22427-22434.
75. VAN DER KEMP, P. A., D. THOMAS, R. BARBEY, R. DE OLIVEIRA and S. BOITEUX, 1996 Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc. Natl. Acad. Sci. USA 93: 5197-5202.
76. WACH, A., A. BRACHAT, R. POHLMANN and P. PHILIPPSEN, 1994 New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10: 1793-1808.
77. WHELAN, W. L., E. GOCKE and T. R. MANNEY, 1979 The CAN1 locus of Saccharomyces cerevisiae: fine-structure analysis and forward mutation rates. Genetics 91: 35-51.
78. WIERDL, M., C. N. GREENE, A. DATTA, S. JINKS-ROBERTSON and T. D. PETES, 1996 Destabilization of simple repetitive DNA sequences by transcription in yeast, Genetics 143: 713-721.
79. XIAO, W., and B. L. CHOW, 1998 Synergism between yeast nucleotide and base excision repair pathways in the protection against DNA methylation damage. Curr. Genet. 33: 92-99.
80. YOU, H. J., R. L. SWANSON and P. W. DOETSCH, 1998 Saccharomyces cerevisiae possesses two functional homologues of Escherichia coli endonuclease III. Biochemistry 37: 6033-6040.