P2X receptor-mediated purinergic sensory pathways to the spinal cord dorsal horn

Purinergic Signalling

Volumn 1, Issue 1, 2004, Pages 11-16

  Gu, Jianguo G ^a   Heft, Marc W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

Author keywords

ATP; P2X receptors; Pain; Primary afferent fibers; Purinergic; Spinal cord dorsal horn; Synaptic transmission

Indexed keywords

ADENOSINE TRIPHOSPHATASE; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR;

ALLODYNIA; DISEASE COURSE; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; NERVE FUNCTION; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PROTEIN FUNCTION; REVIEW; SENSORY NERVE CONDUCTION; SENSORY STIMULATION; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; SPINAL CORD LESION; SYNAPTIC TRANSMISSION;

EID: 20444369928     PISSN: 15739538     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11302-004-4743-6     Document Type: Review

References (55)

1. BS Khakh G Burnstock C Kennedy 2001 International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits Pharmacol Rev 53 107-118
2. RA North 2002 Molecular physiology of P2X receptors Physiol Rev 82 1013-1067
3. G Collo RA North E Kawashima 1996 Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels J Neurosci 16 2495-2507
4. Z Xiang X Bo G Burnstock 1998 Localization of ATP-gated P2X receptor immunoreactivity in rat sensory and sympathetic ganglia Neurosci Lett 256 105-108
5. EC Burgard W Niforatos T Biesen van 1999 P2X receptor-mediated ionic currents in dorsal root ganglion neurons J Neurophysiol 82 1590-1598
6. S Ueno M Tsuda T Iwanaga 1999 Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons Br J Pharmacol 126 429-436
7. C Li RW Peoples TH Lanthorn 1999 Distinct ATP-activated currents in different types of neurons dissociated from rat dorsal root ganglion Neurosci Lett 263 57-60
8. JC Petruska BY Cooper RD Johnson 2000 Distribution patterns of different P2X receptor phenotypes in acutely dissociated dorsal root ganglion neurons of adult rats Exp Brain Res 134 126-132
9. JC Petruska N Mena T Nakatsuka 2000 P2X1 receptor subunit immunoreactivity and ATP-evoked fast currents in adult rat dorsal root ganglion neurons NeuroReport 11 3589-3592
10. K Tsuzuki A Ase P Seguela 2003 TNP-ATP-resistant P2X ionic current on the central terminals and somata of rat primary sensory neurons J Neurophysiol 89 3235-3242
11. C Lewis S Neidhart C Holy 1995 Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons Nature 377 432-435
12. SP Cook L Vulchanova KM Hargreaves 1997 Distinct ATP receptors on pain-sensing and stretch-sensing neurons Nature 387 505-508
13. KM Radford C Virginio A Surprenant 1997 Baculovirus expression provides direct evidence for heteromeric assembly of P2X2 and P2X3 receptors J Neurosci 17 6529-6533
14. M Liu BF King PM Dunn 2001 Coexpression of P2X3 and P2X2 receptor subunits in varying amounts generates heterogeneous populations of P2X receptors that evoke a spectrum of agonist responses comparable to that seen in sensory neurons J Pharmacol Exp Ther 296 1043-1050
15. EC Burgard W Niforatos T van Biesen 2000 Competitive antagonism of recombinant P2X2/3 receptors by 2′, 3′- O -(2,4,6-trinitrophenyl) adenosine 5′-triphosphate (TNP-ATP) Mol Pharmacol 58 1502-1510
16. GY Xu LY Huang 2002 Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons J Neurosci 22 93-102
17. OA Krishtal SM Marchenko VI Pidoplichko 1983 Receptor for ATP in the membrane of mammalian sensory neurones Neurosci Lett 35 41-45
18. CE Jahr TM Jessell 1983 ATP excites a subpopulation of rat dorsal horn neurones Nature 304 730-733
19. CC Chen AN Akopian L Siviltotti 1995 A P2X purinoceptor expressed by a subset of sensory neurons Nature 377 428-431
20. JG Gu AB MacDermott 1997 Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses Nature 389 749-753
21. DA Cockayne SG Hamilton QM Zhu 2000 Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice Nature 407 1011-1015
22. V Souslova P Cesare D Nebenuis-Oosthuizen 2000 Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors Nature 407 1015-1017
23. T Nakatsuka JG Gu 2001 ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord J Neurosci 21 6522-6531
24. T Nakatsuka H Furue M Yoshimura 2002 Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord J Neurosci 22 1228-1237
25. G Burnstock 1996 A unifying purinergic hypothesis for the initiation of pain Lancet 347 1604-1605
26. G Burnstock 2000 P2X receptors in sensory neurones Br J Anaesth 84 476-488
27. D Irnich DJ Tracey J Polten 2002 ATP stimulates peripheral axons in human, rat and mouse - differential involvement of A(2B) adenosine and P2X purinergic receptors Neuroscience 110 123-129
28. J Sawynok A Reid 1997 Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic P2X receptor Eur J Pharmacol 330 115-121
29. E Dowd DS McQueen IP Chessell 1998 P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint Br J Pharmacol 125 341-346
30. M Tsuda S Koizumi A Kita 2000 Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: Involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons J Neurosci 20 RC90
31. G Wynn W Rong Z Xiang 2003 Burnstock G. Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum Gastroenterology 125 1398-1409
32. HV Tempest AK Dixon WH Turner 2004 P2X and P2X receptor expression in human bladder urothelium and changes in interstitial cystitis BJU Int 93 1344-1348
33. SD Novakovic LC Kassotakis IB Oglesby 1999 Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury Pain 80 273-282
34. K Tsuzuki E Kondo T Fukuoka 2001 Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia Pain 91 351-360
35. S McGaraughty CT Wismer CZ Zhu 2003 Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration Br J Pharmacol 140 1381-1388
36. JG Gu 2003 P2X receptor-mediated modulation of sensory transmission to the spinal cord dorsal horn Neuroscientist 9 370-378
37. RE Fyffe ER Perl 1984 Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin? Proc Natl Acad Sci USA 81 6890-6893
38. T Nakatsuka K Tsuzuki J Ling 2003 Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in the dorsal horn of rat spinal cord J Neurophysiol 89 3243-3252
39. BA Chizh P Illes 2001 P2X receptors and nociception Pharmacol Rev 53 553-568
40. B Rexed 1952 The cytoarchitectonic organization of the spinal cord in the rat J Comp Neurol 94 415-466
41. WD Willis Jr RE Coggeshall 1991 Sensory Mechanisms of the Spinal Cord New York: Plenum Press
42. F Cervero 1995 What is a nociceptor-specific (class 3) cell? Pain 62 123-125
43. R Dubner GJ Bennett 1983 Spinal and trigeminal mechanisms of nociception Annu Rev Neurosci 6 381-18
44. S Mense 1993 Nociception from skeletal muscle in relation to clinical muscle pain Pain 54 241-289
45. HG Schaible BD Grubb 1993 Afferent and spinal mechanisms of joint pain Pain 55 5-54
46. TJ Ness GF Gebhart 1990 Visceral pain: A review of experimental studies Pain 41 167-234
47. L Vulchanova MS Riedl SJ Shuster 1998 P2X3 is expressed by DRG neurons that terminate in inner lamina. II Eur J Neurosci 10 3470-3478
48. EJ Bradbury G Burnstock SB McMahon 1998 The expression of P2X3 purinoreceptors in sensory neurons: Effects of axotomy and glial-derived neurotrophic factor Mol Cell Neurosci 12 256-268
49. A Guo L Vulchanova J Wang 1999 Immunocytochemical localization of the vanilloid receptor 1 (VR1): Relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites Eur J Neurosci 11 946-958
50. L Vulchanova U Arvidsson M Riedl 1996 Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry Proc Natl Acad Sci USA 93 8063-8067
51. L Vulchanova MS Riedl SJ Shuster 1997 Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals Neuropharmacology 36 1229-1242
52. P Honore K Kage J Mikusa 2002 Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats Pain 99 11-19
53. G Dorn S Patel G Wotherspoon 2004 siRNA relieves chronic neuropathic pain Nucleic Acids Res 32 e49
54. RA North 2004 P2X3 receptors and peripheral pain mechanisms J Physiol 554 301-308
55. MS Ramer EJ Bradbury SB McMahon 2001 Nerve growth factor induces P2X(3) expression in sensory neurons J Neurochem 77 864-875