ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord

Journal of Neuroscience

Volumn 21, Issue 17, 2001, Pages 6522-6531

  Nakatsuka, Terumasa ^a   Gu, Jianguo G ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

Author keywords

ATP; EPSCs; Glutamate release; Patch clamp technique; Primary afferent fibers; Purinergic receptors; Spinal cord slice preparation

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA,GAMMA DIBROMOMETHYLENE 6 N,N DIETHYLADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CARBENE; GLUTAMIC ACID; PURINE ANTAGONIST; PURINE P2X RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; NERVE CELL STIMULATION; NEUROTRANSMITTER RELEASE; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SPINAL CORD; SPINAL CORD DORSAL HORN; SYNAPTIC TRANSMISSION;

EID: 0035449908     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-17-06522.2001     Document Type: Article

References (46)

1. ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord
2. The dorsal horn of the spinal cord
3. P2X receptor-mediated ionic currents in dorsal root ganglion neurons
4. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
5. Distinct ATP receptors on pain-sensing and stretch-sensing neurons
6. P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint
7. Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses
8. 2+-permeable AMPA receptors
9. 3 purinoceptor, and IB4 binding sites
10. 5 isoforms
11. The capillary dilator substances in dry powers of spinal roots: A possible role for adenosine triphosphate in chemical transmission from nerve endings
12. Presynaptic P2X receptors facilitate inhibitory GABAergic transmission between cultured rat spinal cord dorsal horn neurons
13. ATP excites a subpopulation of rat dorsal horn neurones
14. Synaptic corelease of ATP and GABA in cultured spinal neurons
15. ATP receptor-mediated enhancement of fast excitatory neurotransmitter release in the brain
16. International Union of Pharmacology. XIV. Current status of the nomenclature and properties of P2X receptors and their subunits
17. 5 subunits in Xenopus oocytes
18. Receptor for ATP in the membrane of mammalian sensory neurones
19. Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors
20. 5 subunits
21. 3 receptor subunits can account for ATP-gated currents in sensory neurons
22. Distinct ATP-activated currents in different types of neurons dissociated from rat dorsal root ganglion
23. ATP modulation of synaptic transmission in the spinal substantia gelatinosa
24. ATP P2X receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats
25. Presynaptic ionotropic receptors and the control of transmitter release
26. Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices
27. Alteration in synaptic inputs through C-afferent fibers to substantia gelatinosa neurons of the rat spinal dorsal horn during postnatal development
28. Pharmacology of cloned P2X receptors
29. 3 purinoceptors in sensory neurons in naive rats and following neuropathic injury
30. 3 receptor subunits in rat primary afferents: Relation to population markers and specific cell types
31. A study of the mechanism of the release of ATP from rat cortical astroglial cells evoked by activation of glutamate receptors
32. ATP facilitates spontaneous glycinergic IPSC frequency at dissociated rat dorsal horn interneuron synapses
33. Morphological features of lamina V neurons receiving nociceptive input in cat sacrocaudal spinal cord
34. Physiological roles for adenosine and ATP in synaptic transmission in the spinal dorsal horn
35. Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic P2X receptor
36. 1/5 receptors expressed in HEK cells and excitatory junction potentials in guinea-pig submucosal arterioles
37. 5 receptor subunits reveals a novel ATP-gated ion channel
38. 2/3 receptor signaling in capsaicin-insensitive primary afferent neurons
39. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry
40. 3 receptor subunits in rat and monkey sensory neurons and their central terminals
41. 3 is expressed by DRG neurons that terminate in inner lamina II
42. Enhancement of sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens by the novel ecto-ATPase inhibitor ARL67156
43. + and veratridine-induced release of ATP from synaptosomes prepared from dorsal and ventral spinal cord
44. Localization of ATP-gated P2X receptor immunoreactivity in rat sensory and sympathetic ganglia
45. Monosynaptic input to deep dorsal horn neurons from primary afferent Aδ fibers in the rat spinal cord in vitro