Syntheses and biological activities of rebeccamycin analogues with uncommon sugars

Journal of Medicinal Chemistry

Volumn 48, Issue 7, 2005, Pages 2600-2611

  Zhang, Guisheng ^a   Shen, Jie ^a   Cheng, Hao ^a   Zhu, Lizhi ^a   Fang, Lanyan ^a   Luo, Sanzhong ^a   Muller, Mark T ^b   Lee, Gun Eui ^b   Wei, Lijun ^c   Du, Yuguo ^d   Sun, Duxin ^a   Wang, Peng George ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA   (United States)

^c YUNNAN UNIVERSITY   (China)

^d RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

11,12 DIHYDRO 11 (3 AMINO 2,3,6 TRIDEOXY BETA LEVO LYXOHEXOSYL)INDOLO[2,3 A]CARBAZOLE 5,6 DICARBOXYLIC ANHYDRIDE; 11,12 DIHYDRO 11 (3 BENZOXYAMIDO 2,3,6 TRIDEOXY BETA LEVO LYXOHEXOSYL)INDOLO[2,3 A]CARBAZOLE 5,6 DICARBOXYLIC ANHYDRIDE; 2,3,6 DEOXYGLUCOSE; 2,6 DEOXYGLUCOSE; 6 METHYL 12 (2 DEOXY ALPHA LEVO RHAMNOPYRANOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE; 6 METHYL 12 (2 DEOXY BETA DEXTRO GLUCOPYRANOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE; 6 METHYL 12 (2 DEOXY BETA LEVO RHAMNOPYRANOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE; 6 METHYL 12 (3 BENZOXYAMIDO 2,3,6 TRIDEOXY BETA LEVO LYXOHEXOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE; AGLYCONE; AT 2433 A1; AT 2433 B1; CARBOHYDRATE; CYTOTOXIC AGENT; DAUNORUBICIN; DEOXYGLUCOSE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; GLYCOSIDE; IMIDE; INDOLE DERIVATIVE; INDOLECARBAZOLE DERIVATIVE; REBECCAMYCIN; REBECCAMYCIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; BIOLOGICAL ACTIVITY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DRUG CYTOTOXICITY; DRUG SOLUBILITY; DRUG SYNTHESIS; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VIVO STUDY; LEUKEMIA CELL; MITSUNOBU REACTION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CARBAZOLES; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; INDOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20244380623     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0493764     Document Type: Article

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