메뉴 건너뛰기




Volumn 90, Issue 10, 1999, Pages 1163-1170

In vivo anti-tumor activity of a novel indolocarbazole compound, J-107088, on murine and human tumors transplanted into mice

Author keywords

Anti tumor; Indolocarbazole; J 107088; Metastasis; Toxicity

Indexed keywords

CARBAZOLE DERIVATIVE; CISPLATIN; DNA TOPOISOMERASE; DOXORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; PACLITAXEL;

EID: 0032702777     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1999.tb00691.x     Document Type: Article
Times cited : (49)

References (12)
  • 1
    • 0028931509 scopus 로고
    • Novel antitumor indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a] pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): Induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity
    • Yoshinari, T., Matsumoto, M., Arakawa, H., Okada, H., Noguchi, K., Suda, H., Okura, A. and Nishimura, S. Novel antitumor indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a] pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity. Cancer Res., 55, 1310-1315 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 1310-1315
    • Yoshinari, T.1    Matsumoto, M.2    Arakawa, H.3    Okada, H.4    Noguchi, K.5    Suda, H.6    Okura, A.7    Nishimura, S.8
  • 2
    • 0028905348 scopus 로고
    • Novel indolocarbazole compound 6-N-formylamino-2,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H- indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7(6H)-dione (NB-506): Its potent antitumor activity in mice
    • Arakawa, H., Iguchi, T., Morita, M., Yoshinari, T., Kojiri, K., Suda, H., Okura, A. and Nishimura, S. Novel indolocarbazole compound 6-N-formylamino-2,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H- indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7(6H)-dione (NB-506): its potent antitumor activity in mice. Cancer Res., 55, 1316-1320 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 1316-1320
    • Arakawa, H.1    Iguchi, T.2    Morita, M.3    Yoshinari, T.4    Kojiri, K.5    Suda, H.6    Okura, A.7    Nishimura, S.8
  • 4
    • 0029956091 scopus 로고    scopus 로고
    • Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver
    • Arakawa, H., Matsumoto, H., Morita, M., Sasaki, M., Taguchi, K., Okura, A. and Nishimura, S. Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver. Jpn. J. Cancer Res., 87, 518-523 (1996).
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 518-523
    • Arakawa, H.1    Matsumoto, H.2    Morita, M.3    Sasaki, M.4    Taguchi, K.5    Okura, A.6    Nishimura, S.7
  • 6
    • 0022378065 scopus 로고
    • Activity of a novel 4-quinolinecarboxylic acid, NSC 3688390 [6-fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4- quinolinecarboxylic acid sodium salt], against experimental tumors
    • Dexter, D. L., Hesson, D. P., Ardecky, R. J., Rao, G. V., Tippett, D. L., Dusak, B. A., Paull, K. D., Plowman, J., DeLarco, B. M., Narayanan, V. L. and Forbes, M. Activity of a novel 4-quinolinecarboxylic acid, NSC 3688390 [6-fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4- quinolinecarboxylic acid sodium salt], against experimental tumors. Cancer Res., 45, 5563-5568 (1985).
    • (1985) Cancer Res. , vol.45 , pp. 5563-5568
    • Dexter, D.L.1    Hesson, D.P.2    Ardecky, R.J.3    Rao, G.V.4    Tippett, D.L.5    Dusak, B.A.6    Paull, K.D.7    Plowman, J.8    DeLarco, B.M.9    Narayanan, V.L.10    Forbes, M.11
  • 7
    • 0013909023 scopus 로고
    • Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man
    • Freireich, E. J., Gehan, E. A., Rall, D. P., Schmidt, L. H. and Skipper, H. E. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother. Rep., 50, 219-244 (1966).
    • (1966) Cancer Chemother. Rep. , vol.50 , pp. 219-244
    • Freireich, E.J.1    Gehan, E.A.2    Rall, D.P.3    Schmidt, L.H.4    Skipper, H.E.5
  • 8
    • 0025788486 scopus 로고
    • A new antitumor substance, BE-13793c, produced by a streptomycete. Taxonomy, fermentation, isolation, structure determination and biological activity
    • Kojiri, K., Kondo, H., Yoshinari, T., Arakawa, H., Nakajima, S., Satoh, F., Kawamura, K., Okura, A., Suda, H. and Okanishi, M. A new antitumor substance, BE-13793C, produced by a streptomycete. Taxonomy, fermentation, isolation, structure determination and biological activity. J. Antibiot. (Tokyo), 44, 723-728 (1991).
    • (1991) J. Antibiot. (Tokyo) , vol.44 , pp. 723-728
    • Kojiri, K.1    Kondo, H.2    Yoshinari, T.3    Arakawa, H.4    Nakajima, S.5    Satoh, F.6    Kawamura, K.7    Okura, A.8    Suda, H.9    Okanishi, M.10
  • 9
    • 0027297782 scopus 로고
    • ED-110, a novel indolocarbazole, prevents the growth of experimental tumors in mice
    • Arakawa, H., Iguchi, T., Yoshinari, T., Kojiri, K., Suda, H. and Okura, A. ED-110, a novel indolocarbazole, prevents the growth of experimental tumors in mice. Jpn. J. Cancer Res., 84, 574-581 (1993).
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 574-581
    • Arakawa, H.1    Iguchi, T.2    Yoshinari, T.3    Kojiri, K.4    Suda, H.5    Okura, A.6
  • 12
    • 0033614922 scopus 로고    scopus 로고
    • Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities
    • Bailly, C., Qu, X., Chaires, J. B., Colson, P., Houssier, C., Ohkubo, M., Nishimura, S. and Yoshinari, T. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities. J. Med. Chem., 42, 2927-2935 (1999).
    • (1999) J. Med. Chem. , vol.42 , pp. 2927-2935
    • Bailly, C.1    Qu, X.2    Chaires, J.B.3    Colson, P.4    Houssier, C.5    Ohkubo, M.6    Nishimura, S.7    Yoshinari, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.