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Current Medicinal Chemistry - Anti-Cancer Agents

Volumn 2, Issue 2, 2002, Pages 255-266

Discovery of antitumor indolocarbazoles: Rebeccamycin, NSC 655649, and fluoroindolocarbazoles

(5) Long, Byron H a Rose, William C a Vyas, Dolatrai M a Matson, James A a Forenza, Salvatore a

a BRISTOL MYERS SQUIBB (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,11 DESCHLORO 1,11 DIBROMOREBECCAMYCIN; 1,11 DICHLORO 6 (2 DIETHYLAMINOETHYL) 12,13 DIHYDRO 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 (4 O METHYLGLUCOSIDE); 2 DIETHYLAMINOETHANOL; 6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; 7 OXOSTAUROSPORINE; ANTINEOPLASTIC AGENT; AT 2433 A1; AT 2433 B1; AT2433 A1; AT2433 B1; BMS 250749; BMY 27557; BMY 27557 14; CAMPTOTHECIN; CARBAZOLE DERIVATIVE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ETOPOSIDE; FLUOROINDOLOCARBAZOLE DERIVATIVE; INDOLOCARBAZOLE DERIVATIVE; IRINOTECAN; K 252A; K 252B; REBECCAMYCIN; SINGLE STRANDED DNA; STAUROSPORINE; STAUROSPORINE DERIVATIVE; TENIPOSIDE; TOPOTECAN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; CATALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; DOSE RESPONSE; DRUG DECOMPOSITION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERCALATION COMPLEX; MOUSE; NEUTROPENIA; NONHUMAN; OVARY CANCER; REVIEW; STRUCTURE ACTIVITY RELATION; THROMBOCYTOPENIA;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; CARBAZOLES; DRUG DESIGN; GLUCOSIDES; HUMANS; INDOLES; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036080107 PISSN: 15680118 EISSN: None Source Type: Journal
DOI: 10.2174/1568011023354218 Document Type: Review

Times cited : (100)

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