Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle

Journal of Medicinal Chemistry

Volumn 41, Issue 10, 1998, Pages 1631-1640

  Moreau, Pascale ^a   Anizon, Fabrice ^a   Sancelme, Martine ^a   Prudhomme, Michelle ^a   Bailly, Christian ^b   Carrasco, Carolina ^b   Ollier, Monique ^c   Sevère, Danièle ^d   Riou, Jean François ^d   Fabbro, Doriano ^e   Meyer, Thomas ^e   Aubertin, Anne Marie ^c  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b CENTRE OSCAR LAMBRET   (France)

^c INSERM   (France)

^d SANOFI   (France)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; CARBAZOLE DERIVATIVE; DNA TOPOISOMERASE; HETEROCYCLIC AMINE; IMIDE; REBECCAMYCIN;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; DNA BINDING; DNA CLEAVAGE; DRUG EFFICACY; DRUG SYNTHESIS; ENZYME INHIBITION; LEUKEMIA CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-HIV AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; BACILLUS CEREUS; CANDIDA ALBICANS; CARBAZOLES; DNA; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; ESCHERICHIA COLI; HIV-1; INDOLES; MICE; MICROBIAL SENSITIVITY TESTS; PROTEIN KINASE C; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 15144351325     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970843+     Document Type: Article

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