Antileishmaniai chalcones: Statistical design, synthesis, and three- dimensional quantitative structure-activity relationship analysis

Journal of Medicinal Chemistry

Volumn 41, Issue 24, 1998, Pages 4819-4832

  Nielsen, Simon Feldbæk ^a,b   Christensen, Søren Brøgger ^a   Cruciani, Gabriele ^c   Kharazmi, Arsalan ^d   Liljefors, Tommy ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

^c UNIVERSITY OF PERUGIA   (Italy)

^d Mental Health Center Glostrup   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEISHMANIAL AGENT; CHALCONE DERIVATIVE; ANTITRYPANOSOMAL AGENT; CHALCONE; DRUG DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEISHMANIA DONOVANI; LYMPHOCYTE PROLIFERATION; NONHUMAN; PROMASTIGOTE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; ANIMAL; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CYTOLOGY; DRUG EFFECT; IC 50; IN VITRO STUDY; LYMPHOCYTE; REPRODUCIBILITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CELL DIVISION; CHALCONE; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; LYMPHOCYTES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS;

EID: 0032547898     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980410m     Document Type: Article

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