Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1513-1517

  Meng, Charles Q ^a   Zheng, X Sharon ^a   Ni, Liming ^a   Ye, Zhihong ^a   Simpson, Jacob E ^a   Worsencroft, Kimberly J ^a   Hotema, Martha R ^a   Weingarten, M David ^a   Skudlarek, Jason W ^a   Gilmore, Joshua M ^a   Hoong, Lee K ^a   Hill, Russell R ^a   Marino, Elaine M ^a   Suen, Ki Ling ^a   Kunsch, Charles ^a   Wasserman, Martin A ^a   Sikorski, James A ^a  

^a AtheroGenics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHALCONE DERIVATIVE; PROTEIN INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIGEN EXPRESSION; ARTICLE; DRUG POTENCY; IC 50; LIPOPHILICITY; SUBSTITUTION REACTION;

CHALCONE; HETEROCYCLIC COMPOUNDS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 10744232030     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.021     Document Type: Article

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