Insulin-stimulated Protein Kinase B Phosphorylation on Ser-473 is Independent of Its Activity and Occurs through a Staurosporine-insensitive Kinase

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 25643-25646

  Hill, Michelle M ^a   Andjelkovic, Mirjana ^c   Brazil, Derek P ^a   Ferrari, Stefano ^b   Fabbro, Doriano ^b   Hemmings, Brian A ^d  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; HYDROPHOBICITY; INSULIN; PROTEINS;

APOPTOSIS; PHOSPHORYLATION;

BIOCHEMISTRY;

3' PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; INSULIN; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; SERINE; STAUROSPORINE; STAUROSPORINE INSENSITIVE KINASE; THREONINE; UNCLASSIFIED DRUG; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; C TERMINAL REGULATORY DOMAIN; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HYDROPHOBICITY; IC 50; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; METABOLISM;

ANIMALS; CELL LINE; ENZYME ACTIVATION; INSULIN; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SERINE; SIGNAL TRANSDUCTION; STAUROSPORINE;

EID: 0035854677     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100174200     Document Type: Article

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