메뉴 건너뛰기




Volumn 18, Issue 3, 2005, Pages 179-184

Modulating toll-like receptor signaling as a novel antiinfective approach

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMIQUIMOD; INTERFERON; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; RECEPTOR BLOCKING AGENT; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

EID: 18944407955     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: 10.1358/dnp.2005.18.3.892763     Document Type: Article
Times cited : (12)

References (57)
  • 1
    • 0036195459 scopus 로고    scopus 로고
    • Antimicrobial resistance: A global response
    • Smith, R. and Coast, J. Antimicrobial resistance: A global response. Bull World Health Organ 2002, 80: 126-33.
    • (2002) Bull World Health Organ , vol.80 , pp. 126-133
    • Smith, R.1    Coast, J.2
  • 2
    • 0037197022 scopus 로고    scopus 로고
    • Antifungal drug resistance of pathogenic fungi
    • Kortoyiannis, D. and Lewis, R. Antifungal drug resistance of pathogenic fungi. Lancet 2002, 359: 1135-44.
    • (2002) Lancet , vol.359 , pp. 1135-1144
    • Kortoyiannis, D.1    Lewis, R.2
  • 3
    • 0036207167 scopus 로고    scopus 로고
    • Mechanisms of antimicrobial resistance: Their clinical relevance in the new millennium
    • Sefton, A. Mechanisms of antimicrobial resistance: Their clinical relevance in the new millennium. Drugs 2002, 62: 557-66.
    • (2002) Drugs , vol.62 , pp. 557-566
    • Sefton, A.1
  • 4
    • 0031913291 scopus 로고    scopus 로고
    • Risk factors for the spread of antibiotic-resistant bacteria
    • Gopal, R.G. Risk factors for the spread of antibiotic-resistant bacteria. Drugs 1998, 55: 323-30.
    • (1998) Drugs , vol.55 , pp. 323-330
    • Gopal, R.G.1
  • 5
    • 0037024849 scopus 로고    scopus 로고
    • Staphylococcus aureus resistant to vancomycin - United States 2002
    • Staphylococcus aureus resistant to vancomycin - United States 2002. MMWR Morb Mortal Wkly Rep 2002, 51: 565-7.
    • (2002) MMWR Morb Mortal Wkly Rep , vol.51 , pp. 565-567
  • 7
    • 4244056376 scopus 로고    scopus 로고
    • Resistance in viruses other than HIV
    • Griffiths, P.D. Resistance in viruses other than HIV. Int J Inf Dis 2002, 6: S32-7.
    • (2002) Int J Inf Dis , vol.6
    • Griffiths, P.D.1
  • 10
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov, R. and Janeway, C.A., Jr. Innate immune recognition: Mechanisms and pathways. Immunol Rev 2000, 173: 89-97.
    • (2000) Immunol Rev , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 11
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R., Preston-Hurlburt, P. and Janeway, C.A., Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388: 394-7.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 12
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., Takeda, K. and Kaisho, T. Toll-like receptors: Critical proteins linking innate and acquired immunity. Nat Immunol 2001, 2: 675-80.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 14
    • 0033585011 scopus 로고    scopus 로고
    • Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
    • Lien, E., Sellati, T.J., Yoshimura, A. et al. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem 1999, 274: 33419-25.
    • (1999) J Biol Chem , vol.274 , pp. 33419-33425
    • Lien, E.1    Sellati, T.J.2    Yoshimura, A.3
  • 15
    • 0034002247 scopus 로고    scopus 로고
    • Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
    • Lien, E., Means, T.K., Heine, H. et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest 2000, 105: 497-504.
    • (2000) J Clin Invest , vol.105 , pp. 497-504
    • Lien, E.1    Means, T.K.2    Heine, H.3
  • 16
    • 0032133278 scopus 로고    scopus 로고
    • MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
    • Medzhitov, R.P., Preston-Hurlburt, P., Kopp, E. et al. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell 1998, 2: 253-8.
    • (1998) Mol Cell , vol.2 , pp. 253-258
    • Medzhitov, R.P.1    Preston-Hurlburt, P.2    Kopp, E.3
  • 17
    • 0032526861 scopus 로고    scopus 로고
    • The human toll signaling pathway: Divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6(TRAF6)
    • Muzio, M., Natoli, G., Saccani, S. et al. The human toll signaling pathway: Divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6(TRAF6). J Exp Med 1998, 187: 2097-101.
    • (1998) J Exp Med , vol.187 , pp. 2097-2101
    • Muzio, M.1    Natoli, G.2    Saccani, S.3
  • 18
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • Zhang, F.X., Kirschning, C.J., Mancinelli, R. et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999, 274: 7611-4.
    • (1999) J Biol Chem , vol.274 , pp. 7611-7614
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3
  • 19
    • 0038242875 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways
    • Barton, G.M. and Medzhitov, R. Toll-like receptor signaling pathways. Science 2003, 300: 1524-5.
    • (2003) Science , vol.300 , pp. 1524-1525
    • Barton, G.M.1    Medzhitov, R.2
  • 20
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira, S. and Takeda, K. Toll-like receptor signaling. Nat Rev Immunol 2004, 4: 499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 21
    • 0034610291 scopus 로고    scopus 로고
    • The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
    • Ozinsky, A., Underhill, D.M., Fontenot, J.D. et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA 2000, 97: 13766-71.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13766-13771
    • Ozinsky, A.1    Underhill, D.M.2    Fontenot, J.D.3
  • 22
    • 0034671803 scopus 로고    scopus 로고
    • Evidence for an accessory protein function for toll-like receptor 1 in anti-bacterial responses
    • Wyllie, D.H., Kiss-Toth, E., Visintin, A. et al. Evidence for an accessory protein function for toll-like receptor 1 in anti-bacterial responses. J Immunol 2000, 165: 7125-32.
    • (2000) J Immunol , vol.165 , pp. 7125-7132
    • Wyllie, D.H.1    Kiss-Toth, E.2    Visintin, A.3
  • 23
    • 0035165287 scopus 로고    scopus 로고
    • Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin
    • Hajjar, A.M., O'Mahony, D.S., Ozinsky, A. et al. Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J Immunol 2001, 166: 15-9.
    • (2001) J Immunol , vol.166 , pp. 15-19
    • Hajjar, A.M.1    O'Mahony, D.S.2    Ozinsky, A.3
  • 24
    • 0035399769 scopus 로고    scopus 로고
    • Toll receptors in innate immunity
    • Imler, J.L. and Hoffmann, J.A. Toll receptors in innate immunity. Trends Cell Biol 2001, 11: 304-11.
    • (2001) Trends Cell Biol , vol.11 , pp. 304-311
    • Imler, J.L.1    Hoffmann, J.A.2
  • 25
    • 0034922923 scopus 로고    scopus 로고
    • Discrimination of bacterial lipoproteins by Toll-like receptor 6
    • Takeuchi, O., Kawai, T., Muhlradt, P.F. et al. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001, 13: 933-40.
    • (2001) Int Immunol , vol.13 , pp. 933-940
    • Takeuchi, O.1    Kawai, T.2    Muhlradt, P.F.3
  • 26
    • 0036644042 scopus 로고    scopus 로고
    • Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
    • Takeuchi, O., Sato, S., Horiuchi, T. et al. Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 2002, 169: 10-4.
    • (2002) J Immunol , vol.169 , pp. 10-14
    • Takeuchi, O.1    Sato, S.2    Horiuchi, T.3
  • 27
    • 0036344106 scopus 로고    scopus 로고
    • Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
    • Alexopoulou, L., Thomas, V., Schnare, M. et al. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med 2002, 8: 878-84.
    • (2002) Nat Med , vol.8 , pp. 878-884
    • Alexopoulou, L.1    Thomas, V.2    Schnare, M.3
  • 28
    • 0037033073 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
    • Latz, E., Visintin, A., Lien, E. et al. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J Biol Chem 2002, 277: 47834-43.
    • (2002) J Biol Chem , vol.277 , pp. 47834-47843
    • Latz, E.1    Visintin, A.2    Lien, E.3
  • 29
    • 0037021421 scopus 로고    scopus 로고
    • Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling
    • Zhang, H., Tay, P.N., Cao, W. et al. Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling. FEBS Lett 2003, 532: 171-6.
    • (2003) FEBS Lett , vol.532 , pp. 171-176
    • Zhang, H.1    Tay, P.N.2    Cao, W.3
  • 30
    • 0038448227 scopus 로고    scopus 로고
    • Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling
    • Tapping, R.I. and Tobias, P.S. Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling. J Endotoxin Res 2003, 9: 264-8.
    • (2003) J Endotoxin Res , vol.9 , pp. 264-268
    • Tapping, R.I.1    Tobias, P.S.2
  • 31
    • 0141768248 scopus 로고    scopus 로고
    • Importance of extra- and intracellular domains of TLR1 and TLR2 in NFêB signaling
    • Sandor, F., Latz, E., Re, F. et al. Importance of extra- and intracellular domains of TLR1 and TLR2 in NFêB signaling. J Cell Biol 2003, 162: 1099-110.
    • (2003) J Cell Biol , vol.162 , pp. 1099-1110
    • Sandor, F.1    Latz, E.2    Re, F.3
  • 32
    • 0037066502 scopus 로고    scopus 로고
    • Decoding the patterns of self and nonself by the innate immune system
    • Medzhitov, R. and Janeway, C.A., Jr. Decoding the patterns of self and nonself by the innate immune system. Science 2002, 296: 298-300.
    • (2002) Science , vol.296 , pp. 298-300
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 33
    • 0037178785 scopus 로고    scopus 로고
    • IRAK-M is a negative regulator of Toll-like receptor signaling
    • Kobayashi, K., Hernandez, L.D., Galan, J.E. et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002, 110: 191-202.
    • (2002) Cell , vol.110 , pp. 191-202
    • Kobayashi, K.1    Hernandez, L.D.2    Galan, J.E.3
  • 34
    • 5444223519 scopus 로고    scopus 로고
    • The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
    • Boone, D.L., Turer, E.E., Lee, E.G. et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004, 5: 1052-60.
    • (2004) Nat Immunol , vol.5 , pp. 1052-1060
    • Boone, D.L.1    Turer, E.E.2    Lee, E.G.3
  • 35
    • 0037418749 scopus 로고    scopus 로고
    • Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein
    • O'Reilly, S.M. and Moynagh, P.N. Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein. Biochem Biophys Res Commun 2003, 303: 586-93.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 586-593
    • O'Reilly, S.M.1    Moynagh, P.N.2
  • 36
    • 0242556891 scopus 로고    scopus 로고
    • Toll-like receptors: Balancing host resistance with immune tolerance
    • Pasare, C. and Medzhitov, R. Toll-like receptors: Balancing host resistance with immune tolerance. Curr Opin Immunol 2003, 15: 677-82.
    • (2003) Curr Opin Immunol , vol.15 , pp. 677-682
    • Pasare, C.1    Medzhitov, R.2
  • 37
    • 0037471003 scopus 로고    scopus 로고
    • Pyogenic bacterial infections in humans with IRAK-4 deficiency
    • Picard, C., Puel, A., Bonnet, M. et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003, 299: 2076-9.
    • (2003) Science , vol.299 , pp. 2076-2079
    • Picard, C.1    Puel, A.2    Bonnet, M.3
  • 38
    • 0028875151 scopus 로고
    • Immunomodulating and antiviral activities of the imidazoquinoline S-28463
    • Tomai, M.A., Gibson, S.J., Imbertson, L.M. et al. Immunomodulating and antiviral activities of the imidazoquinoline S-28463. Antiviral Res 1995, 28: 253-64.
    • (1995) Antiviral Res , vol.28 , pp. 253-264
    • Tomai, M.A.1    Gibson, S.J.2    Imbertson, L.M.3
  • 39
    • 0036088492 scopus 로고    scopus 로고
    • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
    • Jurk, M., Heil, F., Vollmer, J. et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002, 6: 499.
    • (2002) Nat Immunol , vol.6 , pp. 499
    • Jurk, M.1    Heil, F.2    Vollmer, J.3
  • 40
    • 0033775777 scopus 로고    scopus 로고
    • Adjuvant activities of immune response modifier R-848: Comparison with CpG ODN
    • Vasilakos, J.P., Smith, R.M, Gibson, S.J. et al. Adjuvant activities of immune response modifier R-848: Comparison with CpG ODN. Cell Immunol 2000, 204: 64-74.
    • (2000) Cell Immunol , vol.204 , pp. 64-74
    • Vasilakos, J.P.1    Smith, R.M.2    Gibson, S.J.3
  • 41
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi, H., Kaisho, T., Takeuchi, O. et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002, 3: 196-200.
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 42
    • 0034460078 scopus 로고    scopus 로고
    • Co-operative induction of pro-inflammatory signaling by Toll-like receptors
    • Ozinsky, A., Smith, K.D., Hume, D. et al. Co-operative induction of pro-inflammatory signaling by Toll-like receptors. J Endotoxin Res 2000, 6: 393-6.
    • (2000) J Endotoxin Res , vol.6 , pp. 393-396
    • Ozinsky, A.1    Smith, K.D.2    Hume, D.3
  • 43
    • 0037114134 scopus 로고    scopus 로고
    • Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs
    • Brawand, P., Fitzpatrick, D.R., Greenfield, B. W. et al. Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs. J Immunol 2002, 169: 6711-9.
    • (2002) J Immunol , vol.169 , pp. 6711-6719
    • Brawand, P.1    Fitzpatrick, D.R.2    Greenfield, B.W.3
  • 44
    • 0037738569 scopus 로고    scopus 로고
    • Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CDS alpha+ DC correlates with unresponsiveness to imidazoquinolines
    • Edwards, A.D., Diebold, S.S., Slack, E.M. et al. Toll-like receptor expression in murine DC subsets: Lack of TLR7 expression by CDS alpha+ DC correlates with unresponsiveness to imidazoquinolines. Eur J Immunol 2003, 33: 827-33.
    • (2003) Eur J Immunol , vol.33 , pp. 827-833
    • Edwards, A.D.1    Diebold, S.S.2    Slack, E.M.3
  • 45
    • 3843103508 scopus 로고    scopus 로고
    • Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways
    • Hochrein, H., Schlatter, B., O'Keeffe, M. et al. Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways. Proc Natl Acad Sci USA 2003, 101: 11416-21.
    • (2003) Proc Natl Acad Sci USA , vol.101 , pp. 11416-11421
    • Hochrein, H.1    Schlatter, B.2    O'Keeffe, M.3
  • 46
    • 0036929868 scopus 로고    scopus 로고
    • Human and mouse plasmacytoid dendritic cells
    • Hochrein, H., O'Keeffe, M. and Wagner, H. Human and mouse plasmacytoid dendritic cells. Hum Immunol 2002, 63: 1103-10.
    • (2002) Hum Immunol , vol.63 , pp. 1103-1110
    • Hochrein, H.1    O'Keeffe, M.2    Wagner, H.3
  • 47
    • 3142697714 scopus 로고    scopus 로고
    • TLR9 is localized in the endoplasmic reticulum prior to Stimulation
    • Leifer, C.A., Kennedy, M.N., Mazzoni, A. et al. TLR9 is localized in the endoplasmic reticulum prior to Stimulation. J Immunol 2004, 173: 1179-83.
    • (2004) J Immunol , vol.173 , pp. 1179-1183
    • Leifer, C.A.1    Kennedy, M.N.2    Mazzoni, A.3
  • 48
    • 0842343142 scopus 로고    scopus 로고
    • Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
    • Heikenwalder, M., Polymenidou, M., Junt, T. et al. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nat Med 2004, 10: 187-92.
    • (2004) Nat Med , vol.10 , pp. 187-192
    • Heikenwalder, M.1    Polymenidou, M.2    Junt, T.3
  • 49
    • 0026442313 scopus 로고
    • Antibiotic-induced release of endotoxin: A reappraisal
    • Hurley, J.C. Antibiotic-induced release of endotoxin: A reappraisal. Clin Infect Dis 1992, 15: 840-54.
    • (1992) Clin Infect Dis , vol.15 , pp. 840-854
    • Hurley, J.C.1
  • 50
    • 0026077469 scopus 로고
    • Differences in release of tumor necrosis factor from THP-1 cells stimulated by filtrates of antibiotic killed Escherichia coli
    • Simon, D.M., Koenig, G. and Trenholme, G.M. Differences in release of tumor necrosis factor from THP-1 cells stimulated by filtrates of antibiotic killed Escherichia coli. J Infect Dis 1991, 164: 800-2.
    • (1991) J Infect Dis , vol.164 , pp. 800-802
    • Simon, D.M.1    Koenig, G.2    Trenholme, G.M.3
  • 51
    • 0031891814 scopus 로고    scopus 로고
    • The significance of endotoxin release in experimental and clinical sepsis in surgical patients: Evidence for antibiotic-induced endotoxin release?
    • Holzheimer, R.G. The significance of endotoxin release in experimental and clinical sepsis in surgical patients: Evidence for antibiotic-induced endotoxin release? Infect 1998, 26: 77-84.
    • (1998) Infect , vol.26 , pp. 77-84
    • Holzheimer, R.G.1
  • 52
    • 3342884306 scopus 로고    scopus 로고
    • Comparative effects of ciprofloxacin and ceftazidime on cytokine production in patients with severe sepsis caused by gram-negative bacteria
    • Gogos, C.A., Skoutelis, A., Lekkou, A. et al. Comparative effects of ciprofloxacin and ceftazidime on cytokine production in patients with severe sepsis caused by gram-negative bacteria. Antimicrob Agents Chemother 2004, 48: 2793-8.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2793-2798
    • Gogos, C.A.1    Skoutelis, A.2    Lekkou, A.3
  • 53
    • 0034932263 scopus 로고    scopus 로고
    • Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs
    • Chen, Y., Lenert, P., Weeratna, R. et al. Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs. Gene Ther 2001, 13: 1024-32.
    • (2001) Gene Ther , vol.13 , pp. 1024-1032
    • Chen, Y.1    Lenert, P.2    Weeratna, R.3
  • 54
    • 85047690873 scopus 로고    scopus 로고
    • Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes
    • Meng, G., Rutz, M., Schiemann, M. et al. Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. J Clin Invest 2004, 113: 1473-81.
    • (2004) J Clin Invest , vol.113 , pp. 1473-1481
    • Meng, G.1    Rutz, M.2    Schiemann, M.3
  • 55
    • 0032506137 scopus 로고    scopus 로고
    • Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin
    • Schimke, J., Mathison, J., Morgiewicz, J. et al. Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin. Proc Natl Acad Sci USA 1998, 95: 13875-80.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13875-13880
    • Schimke, J.1    Mathison, J.2    Morgiewicz, J.3
  • 56
    • 0037309925 scopus 로고    scopus 로고
    • Pathogenesis of sepsis: New concepts and implications for future treatment
    • Bochud, P.Y. and Calandra, T. Pathogenesis of sepsis: New concepts and implications for future treatment. Br Med J 2003, 326: 262-6.
    • (2003) Br Med J , vol.326 , pp. 262-266
    • Bochud, P.Y.1    Calandra, T.2
  • 57
    • 0036136335 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages
    • Sweet, M.J., Campbell, C.C., Sester, D.P. et al. Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. J Immunol 2002, 168: 392-9.
    • (2002) J Immunol , vol.168 , pp. 392-399
    • Sweet, M.J.1    Campbell, C.C.2    Sester, D.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.