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Volumn 1, Issue , 2004, Pages 609-622

Engineering of ES Cell Genomes with Recombinase Systems

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EID: 18844453897     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012436643-5/50070-5     Document Type: Chapter
Times cited : (2)

References (85)
  • 1
    • 0032573418 scopus 로고    scopus 로고
    • Comparative kinetic analysis of FLP and cre recombinases: Mathematical models for DNA binding and recombination
    • Ringrose L., Chabanis S., Angrand P.O., Woodroofe C., Stewart A.F. Comparative kinetic analysis of FLP and cre recombinases: Mathematical models for DNA binding and recombination. J. Mol. Biol. 1998, 284:363-384.
    • (1998) J. Mol. Biol. , vol.284 , pp. 363-384
    • Ringrose, L.1    Chabanis, S.2    Angrand, P.O.3    Woodroofe, C.4    Stewart, A.F.5
  • 2
    • 0034991483 scopus 로고    scopus 로고
    • A structural view of cre/loxp site-specific recombination
    • Van Duyne G.D. A structural view of cre/loxp site-specific recombination. Annu. Rev. Biophys. Biomol. Struct. 2001, 30:87-104.
    • (2001) Annu. Rev. Biophys. Biomol. Struct. , vol.30 , pp. 87-104
    • Van Duyne, G.D.1
  • 3
    • 0041375463 scopus 로고    scopus 로고
    • New insight into site-specific recombination from FLP recombinase-DNA structures
    • Chen Y., Rice P.A. New insight into site-specific recombination from FLP recombinase-DNA structures. Annu. Rev. Biophys. Biomol. Struct. 2003, 32:135-159.
    • (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 135-159
    • Chen, Y.1    Rice, P.A.2
  • 5
    • 0032573147 scopus 로고    scopus 로고
    • Rapid elimination of mature autoreactive B-cells demonstrated by Cre-induced change in B-cell antigen receptor specificity in vivo
    • Lam K.P., Rajewsky K. Rapid elimination of mature autoreactive B-cells demonstrated by Cre-induced change in B-cell antigen receptor specificity in vivo. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:13,171-13,175.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 13171-13175
    • Lam, K.P.1    Rajewsky, K.2
  • 6
    • 0034252563 scopus 로고    scopus 로고
    • Creating a transloxation: engineering interchromosomal translocations in the mouse
    • Testa G., Stewart A.F. Creating a transloxation: engineering interchromosomal translocations in the mouse. EMBO Rep. 2000, 1:120-121.
    • (2000) EMBO Rep. , vol.1 , pp. 120-121
    • Testa, G.1    Stewart, A.F.2
  • 7
    • 0029278832 scopus 로고
    • Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome
    • Albert H., Dale E.C., Lee E., Ow D.W. Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome. Plant J. 1995, 7:649-659.
    • (1995) Plant J. , vol.7 , pp. 649-659
    • Albert, H.1    Dale, E.C.2    Lee, E.3    Ow, D.W.4
  • 8
    • 0030809406 scopus 로고    scopus 로고
    • Targeted integration of DNA using mutant lox sites in embryonic stem cells
    • Araki K., Araki M., Yamamura K. Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res. 1997, 25:868-872.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 868-872
    • Araki, K.1    Araki, M.2    Yamamura, K.3
  • 9
    • 0036727558 scopus 로고    scopus 로고
    • Cre recombinase-mediated inversion using lox66 and lox71: method to introduce conditional point mutations into the CREB-binding protein
    • Zhang Z., Lutz B. Cre recombinase-mediated inversion using lox66 and lox71: method to introduce conditional point mutations into the CREB-binding protein. Nucleic Acids Res. 2002, 30:e90.
    • (2002) Nucleic Acids Res. , vol.30 , pp. e90
    • Zhang, Z.1    Lutz, B.2
  • 10
    • 0028109636 scopus 로고
    • Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci
    • Schlake T., Bode J. Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci. Biochemistry 1994, 33:12,746-12,751.
    • (1994) Biochemistry , vol.33 , pp. 12746-12751
    • Schlake, T.1    Bode, J.2
  • 11
    • 0035476708 scopus 로고    scopus 로고
    • Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes
    • Baer A., Bode J. Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes. Curr. Opin. Biotechnol. 2001, 12:473-480.
    • (2001) Curr. Opin. Biotechnol. , vol.12 , pp. 473-480
    • Baer, A.1    Bode, J.2
  • 12
    • 0344333424 scopus 로고    scopus 로고
    • DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs
    • Seibler J., Schubeler D., Fiering S., Groudine M., Bode J. DNA cassette exchange in ES cells mediated by Flp recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs. Biochemistry 1998, 37:6229-6234.
    • (1998) Biochemistry , vol.37 , pp. 6229-6234
    • Seibler, J.1    Schubeler, D.2    Fiering, S.3    Groudine, M.4    Bode, J.5
  • 13
    • 0032541483 scopus 로고    scopus 로고
    • Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination
    • Lee G., Saito I. Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination. Gene 1998, 216:55-65.
    • (1998) Gene , vol.216 , pp. 55-65
    • Lee, G.1    Saito, I.2
  • 15
    • 0035869499 scopus 로고    scopus 로고
    • Selection marker-free modification of the murine β-casein gene using a lox2272 [correction of lox2722] site
    • Kolb A.F. Selection marker-free modification of the murine β-casein gene using a lox2272 [correction of lox2722] site. Anal. Biochem. 2001, 290:260-271.
    • (2001) Anal. Biochem. , vol.290 , pp. 260-271
    • Kolb, A.F.1
  • 16
    • 0345044372 scopus 로고    scopus 로고
    • Stable and efficient cassette exchange under nonselectable conditions by combined use of two site-specific recombinases
    • Lauth M., Spreafico F., Dethleffsen K., Meyer M. Stable and efficient cassette exchange under nonselectable conditions by combined use of two site-specific recombinases. Nucleic Acids Res. 2002, 30:e115.
    • (2002) Nucleic Acids Res. , vol.30 , pp. e115
    • Lauth, M.1    Spreafico, F.2    Dethleffsen, K.3    Meyer, M.4
  • 17
  • 19
    • 0036229438 scopus 로고    scopus 로고
    • Diversity in the serine recombinases
    • Smith M.C., Thorpe H.M. Diversity in the serine recombinases. Mol. Microbiol. 2002, 44:299-307.
    • (2002) Mol. Microbiol. , vol.44 , pp. 299-307
    • Smith, M.C.1    Thorpe, H.M.2
  • 20
    • 0032510752 scopus 로고    scopus 로고
    • In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase-invertase family
    • Thorpe H.M., Smith M.C. In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase-invertase family. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:5505-5510.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 5505-5510
    • Thorpe, H.M.1    Smith, M.C.2
  • 22
    • 0033745097 scopus 로고    scopus 로고
    • Control of directionality in the site-specific recombination system of the Streptomyces phage phiC31
    • Thorpe H.M., Wilson S.E., Smith M.C. Control of directionality in the site-specific recombination system of the Streptomyces phage phiC31. Mol. Microbiol. 2000, 38:232-241.
    • (2000) Mol. Microbiol. , vol.38 , pp. 232-241
    • Thorpe, H.M.1    Wilson, S.E.2    Smith, M.C.3
  • 23
    • 0036606856 scopus 로고    scopus 로고
    • Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells
    • Andreas S., Schwenk F., Kuter-Luks B., Faust N., Kuhn R. Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells. Nucleic Acids Res. 2002, 30:2299-2306.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2299-2306
    • Andreas, S.1    Schwenk, F.2    Kuter-Luks, B.3    Faust, N.4    Kuhn, R.5
  • 24
    • 0037337299 scopus 로고    scopus 로고
    • Site-specific cassette exchange and germ line transmission with mouse ES cells expressing phiC31 integrase
    • Belteki G., Gertsenstein M., Ow D.W., Nagy A. Site-specific cassette exchange and germ line transmission with mouse ES cells expressing phiC31 integrase. Nat. Biotechnol. 2003, 21:321-324.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 321-324
    • Belteki, G.1    Gertsenstein, M.2    Ow, D.W.3    Nagy, A.4
  • 25
    • 0035008830 scopus 로고    scopus 로고
    • Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase
    • Thyagarajan B., Olivares E.C., Hollis R.P., Ginsburg D.S., Calos M.P. Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase. Mol. Cell Biol. 2001, 21:3926-3934.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 3926-3934
    • Thyagarajan, B.1    Olivares, E.C.2    Hollis, R.P.3    Ginsburg, D.S.4    Calos, M.P.5
  • 28
    • 0031874849 scopus 로고    scopus 로고
    • Improved properties of FLP recombinase evolved by cycling mutagenesis
    • Buchholz F., Angrand P.O., Stewart A.F. Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat. Biotechnol. 1998, 16:657-662.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 657-662
    • Buchholz, F.1    Angrand, P.O.2    Stewart, A.F.3
  • 30
    • 0034754491 scopus 로고    scopus 로고
    • Alteration of Cre recombinase site specificity by substrate-linked protein evolution
    • Buchholz F., Stewart A.F. Alteration of Cre recombinase site specificity by substrate-linked protein evolution. Nat. Biotechnol. 2001, 19:1047-1052.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 1047-1052
    • Buchholz, F.1    Stewart, A.F.2
  • 31
    • 0037007010 scopus 로고    scopus 로고
    • Directed evolution of the site specificity of Cre recombinase
    • Santoro S.W., Schultz P.G. Directed evolution of the site specificity of Cre recombinase. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:4185-4190.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 4185-4190
    • Santoro, S.W.1    Schultz, P.G.2
  • 32
    • 0037423742 scopus 로고    scopus 로고
    • Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site
    • Voziyanov Y., Konieczka J.H., Stewart A.F., Jayaram M. Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site. J. Mol. Biol. 2003, 326:65-76.
    • (2003) J. Mol. Biol. , vol.326 , pp. 65-76
    • Voziyanov, Y.1    Konieczka, J.H.2    Stewart, A.F.3    Jayaram, M.4
  • 33
    • 0035945238 scopus 로고    scopus 로고
    • Directed evolution of a recombinase for improved genomic integration at a native human sequence
    • Sclimenti C.R., Thyagarajan B., Calos M.P. Directed evolution of a recombinase for improved genomic integration at a native human sequence. Nucleic Acids Res. 2001, 29:5044-5051.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 5044-5051
    • Sclimenti, C.R.1    Thyagarajan, B.2    Calos, M.P.3
  • 36
    • 0033485539 scopus 로고    scopus 로고
    • Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances
    • Ringrose L., Chabanis S., Angrand P.O., Woodroofe C., Stewart A.F. Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances. EMBO J. 1999, 18:6630-6641.
    • (1999) EMBO J. , vol.18 , pp. 6630-6641
    • Ringrose, L.1    Chabanis, S.2    Angrand, P.O.3    Woodroofe, C.4    Stewart, A.F.5
  • 37
    • 0035029433 scopus 로고    scopus 로고
    • A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent
    • Vooijs M., Jonkers J., Berns A. A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep. 2001, 2:292-297.
    • (2001) EMBO Rep. , vol.2 , pp. 292-297
    • Vooijs, M.1    Jonkers, J.2    Berns, A.3
  • 38
    • 0034805364 scopus 로고    scopus 로고
    • Polycomb group repression reduces DNA accessibility
    • Fitzgerald D.P., Bender W. Polycomb group repression reduces DNA accessibility. Mol. Cell Biol. 2001, 21:6585-6597.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 6585-6597
    • Fitzgerald, D.P.1    Bender, W.2
  • 39
    • 0031770816 scopus 로고    scopus 로고
    • Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)
    • Herault Y., Rassoulzadegan M., Cuzin F., Duboule D. Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat. Genet. 1998, 20:381-384.
    • (1998) Nat. Genet. , vol.20 , pp. 381-384
    • Herault, Y.1    Rassoulzadegan, M.2    Cuzin, F.3    Duboule, D.4
  • 40
    • 0029562967 scopus 로고
    • Chromosome engineering in mice
    • Ramirez-Solis R., Liu P., Bradley A. Chromosome engineering in mice. Nature 1995, 378:720-724.
    • (1995) Nature , vol.378 , pp. 720-724
    • Ramirez-Solis, R.1    Liu, P.2    Bradley, A.3
  • 41
    • 0030025850 scopus 로고    scopus 로고
    • Transfer of single gene-containing long terminal repeats into the genome of mammalian cells by a retroviral vector carrying the cre gene and the loxP site
    • Choulika A., Guyot V., Nicolas J.F. Transfer of single gene-containing long terminal repeats into the genome of mammalian cells by a retroviral vector carrying the cre gene and the loxP site. J. Virol. 1996, 70:1792-1798.
    • (1996) J. Virol. , vol.70 , pp. 1792-1798
    • Choulika, A.1    Guyot, V.2    Nicolas, J.F.3
  • 42
    • 0030011519 scopus 로고    scopus 로고
    • Self-deleting retrovirus vectors for gene therapy
    • Russ A.P., Friedel C., Grez M., von Melchner H. Self-deleting retrovirus vectors for gene therapy. J. Virol. 1996, 70:4927-4932.
    • (1996) J. Virol. , vol.70 , pp. 4927-4932
    • Russ, A.P.1    Friedel, C.2    Grez, M.3    von Melchner, H.4
  • 43
    • 0035949704 scopus 로고    scopus 로고
    • Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
    • Pfeifer A., Brandon E.P., Kootstra N., Gage F.H., Verma I.M. Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:11,450-11,455.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 11450-11455
    • Pfeifer, A.1    Brandon, E.P.2    Kootstra, N.3    Gage, F.H.4    Verma, I.M.5
  • 45
    • 0035807255 scopus 로고    scopus 로고
    • Mouse model for lung tumorigenesis through Cre-lox-controlled sporadic activation of the K-Ras oncogene
    • Meuwissen R., Linn S.C., van der Valk M., Mooi W.J., Berns A. Mouse model for lung tumorigenesis through Cre-lox-controlled sporadic activation of the K-Ras oncogene. Oncogene 2001, 20:6551-6558.
    • (2001) Oncogene , vol.20 , pp. 6551-6558
    • Meuwissen, R.1    Linn, S.C.2    van der Valk, M.3    Mooi, W.J.4    Berns, A.5
  • 46
    • 0034794191 scopus 로고    scopus 로고
    • Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase
    • Jo D., Nashabi A., Doxsee C., Lin Q., Unutmaz D., Chen J., Ruley H.E. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat. Biotechnol. 2001, 19:929-933.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 929-933
    • Jo, D.1    Nashabi, A.2    Doxsee, C.3    Lin, Q.4    Unutmaz, D.5    Chen, J.6    Ruley, H.E.7
  • 47
    • 0037007121 scopus 로고    scopus 로고
    • Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes
    • Peitz M., Pfannkuche K., Rajewsky K., Edenhofer F. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:4489-4494.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 4489-4494
    • Peitz, M.1    Pfannkuche, K.2    Rajewsky, K.3    Edenhofer, F.4
  • 49
    • 0042909334 scopus 로고    scopus 로고
    • Generating conditional mouse mutants via tetracycline-controlled gene expression
    • Schonig K., Bujard H. Generating conditional mouse mutants via tetracycline-controlled gene expression. Methods Mol. Biol. 2003, 209:69-104.
    • (2003) Methods Mol. Biol. , vol.209 , pp. 69-104
    • Schonig, K.1    Bujard, H.2
  • 50
    • 0035491607 scopus 로고    scopus 로고
    • Conditional control of gene expression in the mouse
    • Lewandoski M. Conditional control of gene expression in the mouse. Nat. Rev. Genet. 2001, 2:743-755.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 743-755
    • Lewandoski, M.1
  • 51
    • 0032692949 scopus 로고    scopus 로고
    • Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice
    • Utomo A.R., Nikitin A.Y., Lee W.H. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nat. Biotechnol. 1999, 17:1091-1096.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1091-1096
    • Utomo, A.R.1    Nikitin, A.Y.2    Lee, W.H.3
  • 52
    • 0036884523 scopus 로고    scopus 로고
    • Stringent doxycycline dependent control of CRE recombinase in vivo
    • Schonig K., Schwenk F., Rajewsky K., Bujard H. Stringent doxycycline dependent control of CRE recombinase in vivo. Nucleic Acids Res. 2002, 30:e134.
    • (2002) Nucleic Acids Res. , vol.30 , pp. e134
    • Schonig, K.1    Schwenk, F.2    Rajewsky, K.3    Bujard, H.4
  • 53
    • 0035876445 scopus 로고    scopus 로고
    • The lac operator-repressor system is functional in the mouse
    • Cronin C.A., Gluba W., Scrable H. The lac operator-repressor system is functional in the mouse. Genes Dev. 2001, 15:1506-1517.
    • (2001) Genes Dev. , vol.15 , pp. 1506-1517
    • Cronin, C.A.1    Gluba, W.2    Scrable, H.3
  • 54
    • 0032836614 scopus 로고    scopus 로고
    • Engineering the mouse genome by site-specific recombination
    • Metzger D., Feil R. Engineering the mouse genome by site-specific recombination. Curr. Opin. Biotechnol. 1999, 10:470-476.
    • (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 470-476
    • Metzger, D.1    Feil, R.2
  • 55
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
    • Danielian P.S., Muccino D., Rowitch D.H., Michael S.K., McMahon A.P. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr. Biol. 1998, 8:1323-1326.
    • (1998) Curr. Biol. , vol.8 , pp. 1323-1326
    • Danielian, P.S.1    Muccino, D.2    Rowitch, D.H.3    Michael, S.K.4    McMahon, A.P.5
  • 56
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs: will they model the next 100?
    • Zambrowicz B.P., Sands A.T. Knockouts model the 100 best-selling drugs: will they model the next 100?. Nat. Rev. Drug Discov. 2003, 2:38-51.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2
  • 57
    • 0742297021 scopus 로고    scopus 로고
    • Conditional knockout mice
    • Kuhn R., Schwenk F. Conditional knockout mice. Methods Mol. Biol. 2003, 209:159-185.
    • (2003) Methods Mol. Biol. , vol.209 , pp. 159-185
    • Kuhn, R.1    Schwenk, F.2
  • 60
    • 0034616928 scopus 로고    scopus 로고
    • Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5-mutant mice
    • Kaul A., Koster M., Neuhaus H., Braun T. Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5-mutant mice. Cell 2000, 102:17-19.
    • (2000) Cell , vol.102 , pp. 17-19
    • Kaul, A.1    Koster, M.2    Neuhaus, H.3    Braun, T.4
  • 62
    • 0031916557 scopus 로고    scopus 로고
    • An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
    • Meyers E.N., Lewandoski M., Martin G.R. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 1998, 18:136-141.
    • (1998) Nat. Genet. , vol.18 , pp. 136-141
    • Meyers, E.N.1    Lewandoski, M.2    Martin, G.R.3
  • 64
    • 0032214652 scopus 로고    scopus 로고
    • A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
    • Bruning J.C., Michael M.D., Winnay J.N., Hayashi T., Horsch D., Accili D., Goodyear L.J., Kahn C.R. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol. Cell 1998, 2:559-569.
    • (1998) Mol. Cell , vol.2 , pp. 559-569
    • Bruning, J.C.1    Michael, M.D.2    Winnay, J.N.3    Hayashi, T.4    Horsch, D.5    Accili, D.6    Goodyear, L.J.7    Kahn, C.R.8
  • 65
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
    • Kulkarni R.N., Bruning J.C., Winnay J.N., Postic C., Magnuson M.A., Kahn C.R. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 1999, 96:329-339.
    • (1999) Cell , vol.96 , pp. 329-339
    • Kulkarni, R.N.1    Bruning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Kahn, C.R.6
  • 66
    • 0035487038 scopus 로고    scopus 로고
    • Gene trap mutagenesis: past, present, and beyond
    • Stanford W.L., Cohn J.B., Cordes S.P. Gene trap mutagenesis: past, present, and beyond. Nat. Rev. Genet. 2001, 2:756-768.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 756-768
    • Stanford, W.L.1    Cohn, J.B.2    Cordes, S.P.3
  • 67
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
    • Friedrich G., Soriano P. Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice. Genes Dev. 1991, 5:1513-1523.
    • (1991) Genes Dev. , vol.5 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 69
    • 0035178138 scopus 로고    scopus 로고
    • Genomewide trapping of genes that encode secreted and transmembrane proteins repressed by oncogenic signaling
    • Gebauer M., von Melchner H., Beckers T. Genomewide trapping of genes that encode secreted and transmembrane proteins repressed by oncogenic signaling. Genome Res. 2001, 11:1871-1877.
    • (2001) Genome Res. , vol.11 , pp. 1871-1877
    • Gebauer, M.1    von Melchner, H.2    Beckers, T.3
  • 70
    • 0032125602 scopus 로고    scopus 로고
    • Inducible expression based on regulated recombination: a single vector strategy for stable expression in cultured cells
    • Angrand P.O., Woodroofe C.P., Buchholz F., Stewart A.F. Inducible expression based on regulated recombination: a single vector strategy for stable expression in cultured cells. Nucleic Acids Res. 1998, 26:3263-3269.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3263-3269
    • Angrand, P.O.1    Woodroofe, C.P.2    Buchholz, F.3    Stewart, A.F.4
  • 71
    • 0036198221 scopus 로고    scopus 로고
    • A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombination
    • Pasqualetti M., Ren S.Y., Poulet M., LeMeur M., Dierich A., Rijli F.M. A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombination. Genesis 2002, 32:109-111.
    • (2002) Genesis , vol.32 , pp. 109-111
    • Pasqualetti, M.1    Ren, S.Y.2    Poulet, M.3    LeMeur, M.4    Dierich, A.5    Rijli, F.M.6
  • 72
    • 0035015769 scopus 로고    scopus 로고
    • Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line
    • Constien R., Forde A., Liliensiek B., Grone H.J., Nawroth P., Hammerling G., Arnold B. Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line. Genesis 2001, 30:36-44.
    • (2001) Genesis , vol.30 , pp. 36-44
    • Constien, R.1    Forde, A.2    Liliensiek, B.3    Grone, H.J.4    Nawroth, P.5    Hammerling, G.6    Arnold, B.7
  • 73
    • 0035170536 scopus 로고    scopus 로고
    • Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain
    • Mao X., Fujiwara Y., Chapdelaine A., Yang H., Orkin S.H. Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain. Blood 2001, 97:324-326.
    • (2001) Blood , vol.97 , pp. 324-326
    • Mao, X.1    Fujiwara, Y.2    Chapdelaine, A.3    Yang, H.4    Orkin, S.H.5
  • 74
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter mouse strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter mouse strain. Nat. Genet. 1999, 21:70-71.
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 75
    • 0031921985 scopus 로고    scopus 로고
    • Selective disruption of genes transiently induced in differentiating mouse embryonic stem cells by using gene trap mutagenesis and site-specific recombination
    • Thorey I.S., Muth K., Russ A.P., Otte J., Reffelmann A., von Melchner H. Selective disruption of genes transiently induced in differentiating mouse embryonic stem cells by using gene trap mutagenesis and site-specific recombination. Mol. Cell Biol. 1998, 18:3081-3088.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3081-3088
    • Thorey, I.S.1    Muth, K.2    Russ, A.P.3    Otte, J.4    Reffelmann, A.5    von Melchner, H.6
  • 76
    • 0033985437 scopus 로고    scopus 로고
    • Engineering mouse chromosomes with Cre/loxP: Range, efficiency, and somatic applications
    • Zheng B., Sage M., Sheppeard E.A., Jurecic V., Bradley A. Engineering mouse chromosomes with Cre/loxP: Range, efficiency, and somatic applications. Mol. Cell Biol. 2000, 20:648-655.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 648-655
    • Zheng, B.1    Sage, M.2    Sheppeard, E.A.3    Jurecic, V.4    Bradley, A.5
  • 77
    • 0028950996 scopus 로고
    • A site-directed chromosomal translocation induced in embryonic stem cells by Cre/loxP recombination
    • Smith A.J., De Sousa M.A., Kwabi-Addo B., Heppell-Parton A., Impey H., Rabbitts P. A site-directed chromosomal translocation induced in embryonic stem cells by Cre/loxP recombination. Nat. Genet. 1995, 9:376-385.
    • (1995) Nat. Genet. , vol.9 , pp. 376-385
    • Smith, A.J.1    De Sousa, M.A.2    Kwabi-Addo, B.3    Heppell-Parton, A.4    Impey, H.5    Rabbitts, P.6
  • 78
    • 0036338128 scopus 로고    scopus 로고
    • Efficient Cre/loxP-induced mitotic recombination in mouse embryonic stem cells
    • Liu P., Jenkins N.A., Copeland N.G. Efficient Cre/loxP-induced mitotic recombination in mouse embryonic stem cells. Nat. Genet. 2002, 30:66-72.
    • (2002) Nat. Genet. , vol.30 , pp. 66-72
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 79
    • 0035984906 scopus 로고    scopus 로고
    • Efficient biallelic mutagenesis with Cre/loxP-mediated interchromosomal recombination
    • Koike H., Horie K., Fukuyama H., Kondoh G., Nagata S., Takeda J. Efficient biallelic mutagenesis with Cre/loxP-mediated interchromosomal recombination. EMBO Rep. 2002, 3:433-437.
    • (2002) EMBO Rep. , vol.3 , pp. 433-437
    • Koike, H.1    Horie, K.2    Fukuyama, H.3    Kondoh, G.4    Nagata, S.5    Takeda, J.6
  • 80
    • 0035490099 scopus 로고    scopus 로고
    • Engineering chromosomal rearrangements in mice
    • Yu Y., Bradley A. Engineering chromosomal rearrangements in mice. Nat. Rev. Genet. 2001, 2:780-790.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 780-790
    • Yu, Y.1    Bradley, A.2
  • 82
    • 0035093218 scopus 로고    scopus 로고
    • Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity
    • Lefebvre L., Dionne N., Karaskova J., Squire J.A., Nagy A. Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity. Nat. Genet. 2001, 27:257-258.
    • (2001) Nat. Genet. , vol.27 , pp. 257-258
    • Lefebvre, L.1    Dionne, N.2    Karaskova, J.3    Squire, J.A.4    Nagy, A.5
  • 83
    • 0033989250 scopus 로고    scopus 로고
    • Nested chromosomal deletions induced with retroviral vectors in mice
    • Su H., Wang X., Bradley A. Nested chromosomal deletions induced with retroviral vectors in mice. Nat. Genet. 2000, 24:92-95.
    • (2000) Nat. Genet. , vol.24 , pp. 92-95
    • Su, H.1    Wang, X.2    Bradley, A.3
  • 85
    • 0034252206 scopus 로고    scopus 로고
    • Interchromosomal recombination of Mll and Af9 genes mediated by cre/loxP in mouse development
    • Collins E.C., Pannell R., Simpson E.M., Forster A., Rabbitts T.H. Interchromosomal recombination of Mll and Af9 genes mediated by cre/loxP in mouse development. EMBO Rep. 2000, 1:127-132.
    • (2000) EMBO Rep. , vol.1 , pp. 127-132
    • Collins, E.C.1    Pannell, R.2    Simpson, E.M.3    Forster, A.4    Rabbitts, T.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.