Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity

Nature Genetics

Volumn 27, Issue 3, 2001, Pages 257-258

  Lefebvre, Louis ^a   Dionne, Nancy ^a   Karaskova, Jana ^b   Squire, Jeremy A ^b   Nagy, Andras ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC G 418;

ARTICLE; HETEROZYGOSITY LOSS; HOMOZYGOSITY; INBREEDING; MUTAGENESIS; PRIORITY JOURNAL; RECESSIVE INHERITANCE; STEM CELL; TRANSGENE;

ANIMALS; FEMALE; GENE TARGETING; GENETIC TECHNIQUES; HOMOZYGOTE; KANAMYCIN KINASE; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, TRANSGENIC; MUTAGENESIS; STEM CELLS;

EID: 0035093218     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/85808     Document Type: Article

References (15)

1. Gene