Inhibition of hepatitis C virus core protein expression in immortalized human hepatocytes induces cytochrome c-independent increase in Apaf-1 and caspase-9 activation for cell death

Virology

Volumn 336, Issue 2, 2005, Pages 198-207

  Meyer, Keith ^a   Basu, Arnab ^a   Saito, Kousuke ^a   Ray, Ratna B ^a   Ray, Ranjit ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apaf 1; Cytochrome c; Hepatitis C virus core protein; Human hepatocytes

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 9; CORE PROTEIN; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR E2F1;

ARTICLE; CELL DEATH; CELL IMMORTALIZATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; GENE EXPRESSION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 9; CASPASES; CELL CYCLE PROTEINS; CELL TRANSFORMATION, VIRAL; CYTOCHROMES C; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, VIRAL; HEPACIVIRUS; HEPATOCYTES; HUMANS; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, ANTISENSE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; VIRAL CORE PROTEINS;

HEPATITIS C VIRUS;

EID: 18844416914     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2005.03.016     Document Type: Article

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