Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors

Journal of Virology

Volumn 72, Issue 12, 1998, Pages 9722-9728

  Shrivastava, Anju ^a   Manna, Sunil K ^a   Ray, Ranjit ^b   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; HEPATITIS C VIRUS; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0031797725     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.12.9722-9728.1998     Document Type: Article

References (56)

1. Baeuerle, P. A., and D. Baltimore. 1996. NF-κB: ten years after. Cell 87:13-20.
2. Baldwin, A. S. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
3. Barba, G., F. Harper, T. Harada, M. Kohara, S. Goulinet, Y. Matsuura, G. Eder, Z. Schaff, M. J. Chapman, T. Miyamura, and C. Brechot. 1997. Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. Proc. Natl. Acad. Sci. USA 94:1200-1205.
4. Beidler, D. R., M. Tewari, M. Freisen, G. Poirier, and V. M. Dixit. 1995. The bacalovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 270:16526-16528.
5. Bertin, J., R. C. Armstrong, S. Ottilie, D. A. Martin, Y. Wang, S. Banks, G. H. Wang, T. G. Senkevich, E. S. Alnemri, B. Moss, M. J. Lenardo, K. J. Tomaselli, and J. I. Cohen. 1997. Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. Proc. Natl. Acad. Sci. USA 94:1172-1176.
6. Cai, Z., M. Korner, N. Tarantino, and S. Chouaib. 1997. IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-induced apoptosis. J. Biol Chem. 272:96-101.
7. Chang, J., Y. Se-Hwan, Y.-G. Cho, S. B. Hwang, Y. S. Hahn, and Y. C. Sung. 1998. Hepatitis C virus core from two different genotypes has an oncogenic potential but is not sufficient for transforming primary rat embryo fibroblasts in cooperation with the H-ras oncogene. J. Virol. 72:3060-3065.
8. Chaturvedi, M. M., R. LaPushin, and B. B. Aggarwal. 1994. Tumor necrosis factor and lymphotoxin. Qualitative and quantitative differences in the mediation of early and late cellular response. J. Biol. Chem. 269:14575-14583.
9. Chen, C., L. You, L. Hwang, and Y. W. Lee. 1997. Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin-β receptor modulates the signal pathway of the lymphotoxin-β receptor. J. Virol. 71:9417-9426.
10. Chu, Z. L., T. A. Mckinsey, L. Liu, J. J. Gentry, M. H. Malim, and D. W. Ballard. 1997. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. Proc. Natl. Acad. Sci. USA 94:10057-10062.
11. Crews, C. M., A. Alessandrini, and R. L. Erikson. 1992. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 258:478-480.
12. Dimitrov, T., P. Krajesi, T. W. Hermiston, A. E. Tollefson, M. Hannink, and W. S. Wold. 1997. Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes. J. Virol. 71:2830-2837.
13. Foletta, V. C., D. H. Segal and D. R. Cohen. 1998. Transcriptional regulation in the immune system: all roads lead to AP-1. J. Leukoc. Biol. 63:139-152.
14. Geissler, M., A. Gesien, K. Tokushige, and J. Wands. 1997. Enhancement of cellular and humorall immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. J. Immunol. 158:1231-1237.
15. Gille, H., A. D. Sharrocks, and P. E. Shaw. 1992. Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358:414-417.
16. Guo, Y. L., B. Kang, and J. R. Williamson. 1998. Inhibition of the expression of mitogen activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J. Biol. Chem. 273:10362-10366.
17. Guo, Y. L., K. Baysal, B. Kang, L. J. Yang, and J. R. Williamson. 1998. Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J. Biol. Chem. 273:4027-4034.
18. Hashimoto, S., A. Ishi, and S. Yonehara. 1991. The E1B oncogene of adenovirus confers cellular resistance to cytotoxity of tumor necrosis factor and monoclonal anti-Fas antibody. Int. Immunol. 3:343-351.
19. Hehner, S. P., T. G. Hofmann, F. Ratter, A. Dumont, W. Droge, and M. L. Schimitz. 1998. Tumor necrosis factor-α-induced cell killing and activation of transcription factor NF-κB are uncoupled in L929 cells. J. Biol. Chem. 273:18117-18121.
20. Holtmann, H., T. Hahn, and D. Wallach. 1988. Interrelated effects of tumor necrosis factor and interleukin 1 on cell viability. Immunobiology 177:7-22.
21. Hu, S., C. Vincenz, M. Buller, and V. M. Dixit. 1997. A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis. J. Biol. Chem. 272: 9621-9624.
22. Karin, M., Z. Liu, and E. Zandi. 1997. AP-1 function and regulation. Curr. Opin. Cell Biol. 9:240-246.
23. Lagging, L. M., K. Meyer, D. Hoft, M. Houghton, R. B. Belshe, and R. Ray. 1995. Immune responses to plasmid DNA encoding the hepatitis C virus core protein. J. Virol. 69:5859-5863.
24. Lenczowski, J. M., L. Dominguez, A. M. Eder, L. B. King, C. M. Zacharchuk, and J. D. Ashwell. 1997. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mil. Cell. Biol. 17:170-181.
25. Li, Y. and A. K. Jaiswal. 1992. Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element. J. Biol. Chem. 267:15097-15104.
26. Limbourg, F. P., H. Stadtler, G. Chinnadurai, P. A. Baeuerle, and M. L. Schmitz. 1996. A hydrophobic region within the adenovirus E1B 19 kDa protein is necessary for the transient inhibition of NF-kappaB activated by different stimuli. J. Biol. Chem. 271:20392-20398.
27. Liu, Z., H. Hsu, D. V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87:565-576.
28. Major, M. E., L. Vitvitski, M. A. Mink, M. Schleef, R. G. Whalen, C. Trepo, and G. Inchauspe. 1995. DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J. Virol. 69:1798-5805.
29. Maniatis, T., L. A. Whittemore, W. Du, C. M. Fan, A. Keller, V. Palombella, and D. Thanos. 1992. Positive and negative control of human interferon-β gene expression, p. 1193-1220. In S. L. Mcknight and K. Yamamoto (ed)., Transcriptional regulation, part 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
30. Manna, S. K., H. J. Zhang, T. Yan, L. W. Oberley, and B. B. Aggarwal. 1998. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-κB and activated protein-1. J. Biol. Chem. 273:13245-13254.
31. Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-383.
32. Matsumoto, M., T.-Y. Hsieh, N. Zhu, T. VanArsdale, S. B. Hwang, K.-S. Jeng, A. E. Gorbalenya, S.-Y. Lo, J.-S. Ou, C. F. Ware, and M. M. C. Lai. 1997. Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-β receptor. J. Virol. 71:1301-1309.
33. Mendoza, E. C., T. G. Paglieroni, and J. B. Zeldis. 1996. Decreased phorbol myristate acetate-induced release of tumor necrosis factor-alpha and interleukin-1 beta from peripheral blood monocytes of patients chronically infected with hepatitis C virus. J. Infect. Dis. 174:842-844.
34. 2 and antioxidants have opposite effects on activation of NF-kappaB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 12:2005-2015.
35. Minden, A., A. Lin, M. McMahon, C. Lange-Carter, B. Derijard, R. J. Davis, G. L. Johnson, and M. Karin. 1994. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 266:1719-1723.
36. Ray, R. B., L. M. Lagging, K. Meyer, R. Steele, and R. Ray. 1995. Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein. Virus Res. 37:209-220.
37. Ray, R. B., L. M. Lagging, K. Meyer, and R. Ray. 1996. Hepatitis C Virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J. Virol. 70:4438-4443.
38. Ray, R. B., K. Meyer, and R. Ray. 1996. Suppression of apoptopic cell death by hepatitis C virus core protein. Virology 226:176-182.
39. Ray, R. B., R. Steele, K. Meyer, and R. Ray. 1997. Transcriptional repression of p53 promoter by hepatitis C virus core protein. J. Biol. Chem. 272:10983-10986.
40. Ray, R. B., K. Meyer, R. Steele, A. Shrivastava, B. B. Aggarwal, and R. Ray. 1998. Inhibition of tumor necrosis factor (TNF-α) mediated apoptosis by hepatitis C virus core protein. J. Biol. Chem. 273:2256-2259.
41. Ray, R. B., R. Steele, K. Meyer, and R. Ray. 1998. Hepatitis C virus core protein represses p21 WAF1/Cip1/Sid1 promoter activity. Gene 208:331-336.
42. Reddy, S. A., M. M. Chaturvedi, B. G. Darnay, H. Chan, M. Higuchi, and B. B. Aggarwal. 1994. Reconstitution of nuclear factor kappa B activation induced by tumor necrosis factor requires membrane-associated components. Comparison with pathway activated by ceramide. J. Biol. Chem. 269: 25369-25372.
43. Roulston, A., C. Reinhard, P. Amiri, and L. T. Williams. 1998. Early activation of c-Jun N-terminal kinase and P38 kinase regulate cell survival in response to tumor necrosis factor-α. J. Biol. Chem. 273:10232-10239.
44. Rudin, C. M., and C. B. Thompson. 1997. Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annu. Rev. Med. 48:267-281.
45. Ruster B., S. Zeuzem, and W. K. Roth. 1996. Hepatitis C virus sequences encoding truncated core proteins detected in a hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 219:911-915.
46. Saito, I., T. Miyamura, A. Ohbayashi, H. Harada, T. Katayama, S. Kikuchi, Y. Watanabe, S. Koi, M. Onji, Q.-L. Choo, M. Houghton, and G. Kuo. 1990. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc. Natl. Acad. Sci USA 87:6547-6549.
47. Schmidt, K. N., E. B. Traenckner, B. Beier, and P. A. Baeuerle. 1995. Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-κB. J. Biol. Chem. 270:27136-27142.
48. Schreiber, E., P. Matthias, M. M. Muller, and W. W. Schaffner. 1989. Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells. Nucleic Acids Res. 17:6419.
49. Shib, C. M., S. J. Lo, T. Miyamura, S. Y. Chen, and Y. W. Lee. 1993. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells. J. Viol. 67:5823-5832.
50. Shimizu, I., D.-F. Yao, C. Horie, M. Yasuda, M. Shiba, T. Horie, T. Nishikado, X.-Y. Meng, and S. Ho. 1997. Mutations in a hydrophilic part of the core gene of hepatitis C virus in patients with hepatocellular carcinoma in China. J. Gastroenterol. 32:47-55.
51. Singh, S., and B. B. Aggarwal. 1995. Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B. J. Biol. Chem. 270:10631-10639.
52. Thonos, D., and T. Maniathis. 1995. NF-κB: a lesson in family values. Cell 80:529-532.
53. White, E. 1996. Life, death, and the pursuit of apoptosis. Genes Dev. 10:1-15.
54. Wright, K. L., L. C. White, A. Kelly, S. Beck, J. Trowsdale, and J. P. Ting. 1995. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J. Exp. Med. 181:1459-1471.
55. Yasui, K., T. Wakita, K. Tsukiama-Kohara, S. Funahashi, M. Ichikawas, T. Kajita, D. Moradpour, J. R. Wands, and M. Kohara. 1998. The native form and maturation process of hepatitis C virus core protein. J. Virol. 72:6048-6055.
56. Yeh, C.-T., S.-C. Lu, C.-M. Chu, and Y.-F. Liaw. 1997. Molecular cloning of a defective hepatitts C virus genome for the ascitic fluid of a patient with hepatocellular carcinoma. J. Gen. Virol. 78:2761-2770.