The Adapter Protein Apoptotic Protease-activating Factor-1 (Apaf-1) Is Proteolytically Processed during Apoptosis

Journal of Biological Chemistry

Volumn 276, Issue 32, 2001, Pages 29772-29781

  Lauber, Kirsten ^a   Appel, Helga A E ^a   Schlosser, Stephan F ^a   Gregor, Michael ^a   Schulze Osthoff, Klaus ^b   Wesselborg, Sebastian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHEMICAL ACTIVATION; ENZYME KINETICS; OLIGOMERS; PROTEINS;

APOPTOSIS; PROTEOLYSIS;

BIOCHEMISTRY;

ADAPTOR PROTEIN; APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CAENORHABDITIS ELEGANS PROTEIN; CASPASE 9; CYTOCHROME C; DEOXYADENOSINE TRIPHOSPHATE; ENZYME PRECURSOR; OLIGOMER; PROCASPASE 9; PROTEIN; PROTEIN CED 4; PROTEIN P84; UNCLASSIFIED DRUG; WD 40 REPEAT PROTEIN; ADENOSINE TRIPHOSPHATE; APAF1 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP6 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 3; CASPASE 6; CASPASE 8; ENZYME INHIBITOR; ETOPOSIDE; FAS ANTIGEN; MITOMYCIN; NUCLEIC ACID SYNTHESIS INHIBITOR; STAUROSPORINE;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CASPASE RECRUITMENT DOMAIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CHEMISTRY; DOSE RESPONSE; HELA CELL; IMMUNOBLOTTING; LEUKEMIA CELL LINE; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TIME;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

ADENOSINE TRIPHOSPHATE; ANTIGENS, CD95; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; CASPASES; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ETOPOSIDE; HELA CELLS; HUMANS; IMMUNOBLOTTING; JURKAT CELLS; MITOMYCIN; MODELS, BIOLOGICAL; MUTATION; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; STAUROSPORINE; TIME FACTORS;

EID: 0035839575     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101524200     Document Type: Article

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