메뉴 건너뛰기




Volumn 331, Issue 4, 2005, Pages 1089-1098

MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria

Author keywords

Apoptosis; JNK; MEKK1; Mitochondria; Smac Diablo

Indexed keywords

CYTOCHROME C; ETOPOSIDE; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

EID: 18844399612     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.03.234     Document Type: Article
Times cited : (10)

References (40)
  • 1
    • 0032549670 scopus 로고    scopus 로고
    • Caspase-dependent cleavage of signaling proteins during apoptosis. a turn-off mechanism for anti-apoptotic signals
    • C. Widmann, S. Gibson, and G.L. Johnson Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals J. Biol. Chem. 273 1998 7141 7147
    • (1998) J. Biol. Chem. , vol.273 , pp. 7141-7147
    • Widmann, C.1    Gibson, S.2    Johnson, G.L.3
  • 2
    • 9844247987 scopus 로고    scopus 로고
    • Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1
    • C. Widmann, N.L. Johnson, A.M. Gardner, R.J. Smith, and G.L. Johnson Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1 Oncogene 15 1997 2439 2447
    • (1997) Oncogene , vol.15 , pp. 2439-2447
    • Widmann, C.1    Johnson, N.L.2    Gardner, A.M.3    Smith, R.J.4    Johnson, G.L.5
  • 3
    • 0031954631 scopus 로고    scopus 로고
    • MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
    • C. Widmann, P. Gerwins, N.L. Johnson, M.B. Jarpe, and G.L. Johnson MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis Mol. Cell. Biol. 18 1998 2416 2429
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2416-2429
    • Widmann, C.1    Gerwins, P.2    Johnson, N.L.3    Jarpe, M.B.4    Johnson, G.L.5
  • 4
    • 0027215820 scopus 로고
    • A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
    • C.A. Lange-Carter, C.M. Pleiman, A.M. Gardner, K.J. Blumer, and G.L. Johnson A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf Science 260 1993 315 319
    • (1993) Science , vol.260 , pp. 315-319
    • Lange-Carter, C.A.1    Pleiman, C.M.2    Gardner, A.M.3    Blumer, K.J.4    Johnson, G.L.5
  • 5
    • 0034164455 scopus 로고    scopus 로고
    • The c-Jun N-terminal kinase pathway and apoptotic signaling (review)
    • Y.R. Chen, and T.H. Tan The c-Jun N-terminal kinase pathway and apoptotic signaling (review) Int. J. Oncol. 16 2000 651 662
    • (2000) Int. J. Oncol. , vol.16 , pp. 651-662
    • Chen, Y.R.1    Tan, T.H.2
  • 6
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • M. Leist, and M. Jaattela Four deaths and a funeral: from caspases to alternative mechanisms Nat. Rev. Mol. Cell Biol. 2 2001 589 598
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 7
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • A. Ashkenazi, and V.M. Dixit Death receptors: signaling and modulation Science 281 1998 1305 1308
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 8
    • 0037155927 scopus 로고    scopus 로고
    • MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c Release
    • E.M. Gibson, E.S. Henson, J. Villanueva, and S.B. Gibson MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c Release J. Biol. Chem. 277 2002 10573 10580
    • (2002) J. Biol. Chem. , vol.277 , pp. 10573-10580
    • Gibson, E.M.1    Henson, E.S.2    Villanueva, J.3    Gibson, S.B.4
  • 10
    • 0141953270 scopus 로고    scopus 로고
    • A JNK-dependent pathway is required for TNFalpha-induced apoptosis
    • Y. Deng, X. Ren, L. Yang, Y. Lin, and X. Wu A JNK-dependent pathway is required for TNFalpha-induced apoptosis Cell 115 2003 61 70
    • (2003) Cell , vol.115 , pp. 61-70
    • Deng, Y.1    Ren, X.2    Yang, L.3    Lin, Y.4    Wu, X.5
  • 11
    • 0036141029 scopus 로고    scopus 로고
    • TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
    • Y. Deng, Y. Lin, and X. Wu TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO Genes Dev. 16 2002 33 45
    • (2002) Genes Dev. , vol.16 , pp. 33-45
    • Deng, Y.1    Lin, Y.2    Wu, X.3
  • 12
    • 0035816553 scopus 로고    scopus 로고
    • Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells
    • D. Chauhan, T. Hideshima, S. Rosen, J.C. Reed, S. Kharbanda, and K.C. Anderson Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells J. Biol. Chem. 276 2001 24453 24456
    • (2001) J. Biol. Chem. , vol.276 , pp. 24453-24456
    • Chauhan, D.1    Hideshima, T.2    Rosen, S.3    Reed, J.C.4    Kharbanda, S.5    Anderson, K.C.6
  • 14
  • 16
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
    • C. Widmann, S. Gibson, M.B. Jarpe, and G.L. Johnson Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human Physiol. Rev. 79 1999 143 180
    • (1999) Physiol. Rev. , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 20
    • 0036341291 scopus 로고    scopus 로고
    • Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
    • S. Fulda, W. Wick, M. Weller, and K.M. Debatin Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo Nat. Med. 8 2002 808 815
    • (2002) Nat. Med. , vol.8 , pp. 808-815
    • Fulda, S.1    Wick, W.2    Weller, M.3    Debatin, K.M.4
  • 21
    • 0037442965 scopus 로고    scopus 로고
    • Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide
    • L. Yang, T. Mashima, S. Sato, M. Mochizuki, H. Sakamoto, T. Yamori, T. Oh-Hara, and T. Tsuruo Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide Cancer Res. 63 2003 831 837
    • (2003) Cancer Res. , vol.63 , pp. 831-837
    • Yang, L.1    Mashima, T.2    Sato, S.3    Mochizuki, M.4    Sakamoto, H.5    Yamori, T.6    Oh-Hara, T.7    Tsuruo, T.8
  • 22
    • 14944340997 scopus 로고    scopus 로고
    • Anti-tumor chemotherapy utilizing peptide-based approaches-apoptotic pathways, kinases, and proteasome as targets
    • F.J. Mendoza, P.S. Espino, K.L. Cann, N. Bristow, K. McCrea, and M. Los Anti-tumor chemotherapy utilizing peptide-based approaches-apoptotic pathways, kinases, and proteasome as targets Arch. Immunol. Ther. Exp. (Warsz) 53 2005 47 60
    • (2005) Arch. Immunol. Ther. Exp. (Warsz) , vol.53 , pp. 47-60
    • Mendoza, F.J.1    Espino, P.S.2    Cann, K.L.3    Bristow, N.4    McCrea, K.5    Los, M.6
  • 23
    • 0141962476 scopus 로고    scopus 로고
    • The saintly side of Smac/DIABLO: Giving anticancer drug-induced apoptosis a boost
    • C.R. Arnt, and S.H. Kaufmann The saintly side of Smac/DIABLO: giving anticancer drug-induced apoptosis a boost Cell Death Differ. 10 2003 1118 1120
    • (2003) Cell Death Differ. , vol.10 , pp. 1118-1120
    • Arnt, C.R.1    Kaufmann, S.H.2
  • 24
    • 4644244279 scopus 로고    scopus 로고
    • Medicine. Targeting apoptotic pathways in cancer cells
    • C. Denicourt, and S.F. Dowdy Medicine. Targeting apoptotic pathways in cancer cells Science 305 2004 1411 1413
    • (2004) Science , vol.305 , pp. 1411-1413
    • Denicourt, C.1    Dowdy, S.F.2
  • 25
    • 0037085380 scopus 로고    scopus 로고
    • Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization
    • M. Madesh, B. Antonsson, S.M. Srinivasula, E.S. Alnemri, and G. Hajnoczky Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization J. Biol. Chem. 277 2002 5651 5659
    • (2002) J. Biol. Chem. , vol.277 , pp. 5651-5659
    • Madesh, M.1    Antonsson, B.2    Srinivasula, S.M.3    Alnemri, E.S.4    Hajnoczky, G.5
  • 26
    • 9244260553 scopus 로고    scopus 로고
    • Kinetics of Smac/DIABLO release from mitochondria during apoptosis of MCF-7 breast cancer cells
    • M. Gorka, M.M. Godlewski, B. Gajkowska, U. Wojewodzka, and T. Motyl Kinetics of Smac/DIABLO release from mitochondria during apoptosis of MCF-7 breast cancer cells Cell Biol. Int. 28 2004 741 754
    • (2004) Cell Biol. Int. , vol.28 , pp. 741-754
    • Gorka, M.1    Godlewski, M.M.2    Gajkowska, B.3    Wojewodzka, U.4    Motyl, T.5
  • 27
    • 0037379739 scopus 로고    scopus 로고
    • Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: Differential regulation of cytochrome c and Smac/DIABLO release
    • K. Kandasamy, S.M. Srinivasula, E.S. Alnemri, C.B. Thompson, S.J. Korsmeyer, J.L. Bryant, and R.K. Srivastava Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release Cancer Res. 63 2003 1712 1721
    • (2003) Cancer Res. , vol.63 , pp. 1712-1721
    • Kandasamy, K.1    Srinivasula, S.M.2    Alnemri, E.S.3    Thompson, C.B.4    Korsmeyer, S.J.5    Bryant, J.L.6    Srivastava, R.K.7
  • 28
    • 0032483967 scopus 로고    scopus 로고
    • Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
    • T. Yujiri, S. Sather, G.R. Fanger, and G.L. Johnson Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption Science 282 1998 1911 1914
    • (1998) Science , vol.282 , pp. 1911-1914
    • Yujiri, T.1    Sather, S.2    Fanger, G.R.3    Johnson, G.L.4
  • 29
    • 0033499801 scopus 로고    scopus 로고
    • BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
    • K. Yamamoto, H. Ichijo, and S.J. Korsmeyer BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M Mol. Cell. Biol. 19 1999 8469 8478
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8469-8478
    • Yamamoto, K.1    Ichijo, H.2    Korsmeyer, S.J.3
  • 30
    • 0037179867 scopus 로고    scopus 로고
    • MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage
    • A.H. Bild, F.J. Mendoza, E.M. Gibson, M. Huang, J. Villanueva, T.P. Garrington, R. Jove, G.L. Johnson, and S.B. Gibson MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage Oncogene 21 2002 6649 6656
    • (2002) Oncogene , vol.21 , pp. 6649-6656
    • Bild, A.H.1    Mendoza, F.J.2    Gibson, E.M.3    Huang, M.4    Villanueva, J.5    Garrington, T.P.6    Jove, R.7    Johnson, G.L.8    Gibson, S.B.9
  • 31
    • 0033574434 scopus 로고    scopus 로고
    • Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents
    • S. Gibson, C. Widmann, and G.L. Johnson Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents J. Biol. Chem. 274 1999 10916 10922
    • (1999) J. Biol. Chem. , vol.274 , pp. 10916-10922
    • Gibson, S.1    Widmann, C.2    Johnson, G.L.3
  • 33
    • 3242755146 scopus 로고    scopus 로고
    • Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis
    • K. Shimada, S. Matsuyoshi, M. Nakamura, E. Ishida, M. Kishi, and N. Konishi Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis Carcinogenesis 25 2004 1089 1097
    • (2004) Carcinogenesis , vol.25 , pp. 1089-1097
    • Shimada, K.1    Matsuyoshi, S.2    Nakamura, M.3    Ishida, E.4    Kishi, M.5    Konishi, N.6
  • 34
    • 2942696322 scopus 로고    scopus 로고
    • Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells
    • A. Huwiler, C. Xin, A.K. Brust, V.A. Briner, and J. Pfeilschifter Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells Biochim. Biophys. Acta 1636 2004 159 168
    • (2004) Biochim. Biophys. Acta , vol.1636 , pp. 159-168
    • Huwiler, A.1    Xin, C.2    Brust, A.K.3    Briner, V.A.4    Pfeilschifter, J.5
  • 35
    • 0038353609 scopus 로고    scopus 로고
    • TNF-induced death of adult human oligodendrocytes is mediated by c-jun NH2-terminal kinase-3
    • A. Jurewicz, M. Matysiak, K. Tybor, and K. Selmaj TNF-induced death of adult human oligodendrocytes is mediated by c-jun NH2-terminal kinase-3 Brain 126 2003 1358 1370
    • (2003) Brain , vol.126 , pp. 1358-1370
    • Jurewicz, A.1    Matysiak, M.2    Tybor, K.3    Selmaj, K.4
  • 36
    • 0037330477 scopus 로고    scopus 로고
    • The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways
    • S. Boldt, U.H. Weidle, and W. Kolch The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways Exp. Cell Res. 283 2003 80 90
    • (2003) Exp. Cell Res. , vol.283 , pp. 80-90
    • Boldt, S.1    Weidle, U.H.2    Kolch, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.