Targeting apoptotic pathways in cancer cells

Science

Volumn 305, Issue 5689, 2004, Pages 1411-1413

  Denicourt, Catherine ^a   Dowdy, Steven F ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE DERIVATIVE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; 1,6 BIS(4,7 DIAZA 6 METHYL 5 OXO 3 ((2 ((5 (PHENYLTHIO)TETRAZOL 1 YL)METHYL)PYRROLIDIN 1 YL)CARBONYL)OCTYLOXY) 2,4 HEXADIYNE; 1,6-BIS(4,7-DIAZA-6-METHYL-5-OXO-3-((2-((5-(PHENYLTHIO)TETRAZOL-1-YL)METHYL)PYRROLIDIN-1-YL)CARBONYL)OCTYLOXY)-2,4-HEXADIYNE; ALKYNE; ALKYNE DERIVATIVE; BAX PROTEIN (53 86); BAX PROTEIN (53-86); BRIDGED COMPOUND; CARRIER PROTEIN; DIABLO PROTEIN, HUMAN; DIABLO PROTEIN, MOUSE; INHIBITOR OF APOPTOSIS PROTEIN; LIGAND; MITOCHONDRIAL PROTEIN; ONCOPROTEIN; PEPTIDE; PEPTIDE FRAGMENT; PEPTIDE LIBRARY; PROTEIN; SIGNAL PEPTIDE; TETRAZOLE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

CANCER; MEDICINE;

APOPTOSIS; CANCER CELL; CANCER THERAPY; CELL DIVISION; CELL MEMBRANE; DRUG TARGETING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; AMINO ACID SUBSTITUTION; ANIMAL; CANCER INVASION; CHEMISTRY; DRUG ANTAGONISM; ENDOCYTOSIS; EXPERIMENTAL LEUKEMIA; GLIOBLASTOMA; HUMAN; METABOLISM; MOLECULAR MIMICRY; MOUSE; NOTE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

ALKYNES; AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; BRIDGED COMPOUNDS; CARRIER PROTEINS; CELL MEMBRANE; DIYNES; ENDOCYTOSIS; GLIOBLASTOMA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, EXPERIMENTAL; LEUKEMIC INFILTRATION; LIGANDS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR MIMICRY; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; PROTO-ONCOGENE PROTEINS; TETRAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644244279     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1102974     Document Type: Review

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