Molecular targets for design of novel inhibitors to circumvent aminoglycoside resistance

Current Drug Targets

Volumn 6, Issue 3, 2005, Pages 353-361

  Jana, S ^a   Deb, J K ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

Aminoglycoside resistance; Antisense technology; N acetyltransferases; O adenyltransferases; O phosphotransferases

Indexed keywords

ACYLTRANSFERASE; ADENOSINE TRIPHOSPHATE; AMINOCYCLITOL; AMINOGLYCOSIDE ACETYLTRANSFERASE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOGLYCOSIDE DERIVATIVE; AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE; AMINOGLYCOSIDE PHOSPHOTRANSFERASE; ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; APRAMYCIN; BACTERIAL RNA; BETA LACTAM; CHLORAMPHENICOL; DIBEKACIN; ENZYME INHIBITOR; GENTAMICIN; KANAMYCIN A; KANAMYCIN B; LIVIDOMYCIN; NEOMYCIN; NETILMICIN; NITRO DERIVATIVE; NORFLOXACIN; NUCLEOTIDYLTRANSFERASE; O ADENYLTRANSFERASE; O PHOSPHOTRANSFERASE; PAROMOMYCIN; PEPTIDE NUCLEIC ACID; PHOSPHOTRANSFERASE; RIBONUCLEASE P; RIBOSOME RNA; RIBOSTAMYCIN; SUICIDE SUBSTRATE; TOBRAMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; CHEMICAL MODIFICATION; DRUG BINDING SITE; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME SUBSTRATE COMPLEX; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; NONHUMAN; REVIEW; SIDE EFFECT;

AMINOGLYCOSIDES; BINDING SITES; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; KANAMYCIN KINASE; NUCLEOTIDYLTRANSFERASES; OLIGONUCLEOTIDES, ANTISENSE;

EID: 18744378885     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450053765860     Document Type: Review

References (79)

1. Mingeot-Leclercq, M.-P.; Glupczynski, Y.; Tulkens, P. M. Antimicrob. Agents Chemother., 1999, 43, 727-737.
2. Davies, J. and Wright, G. D. Trends Microbiol., 1997, 5, 234-240.
3. Allsop, A. E. Curr. Opin. Microbiol., 1998, 1, 530-534.
4. Mingeot-Leclercq, M.-P.; Tulkens, P.M. Antimicrob. Agents Chemother., 1999, 43, 1003-1012.
5. Fourmy, D.; Yoshizawa, S.; Puglisi, J. D. J. Mol. Biol., 1998, 277, 333-345.
6. Jiang, L. and Patel, D.L Nat. Struct. Biol., 1998, 5, 769-774.
7. Carter, A. P.; Clemons, W. M.; Brodersen, D. E.; Morgan-Warren, R-J.; Wimberly, B. T.; Ramakrishnan, V. Nature, 2000, 407, 340-348.
8. Davies, J. and Wright, G. D. Trends Microbiol., 1997, 5, 234-240.
9. Haddad, J.; Vakulenko, S.; Mobashery, S. J. Am. Chem. Soc., 1999, 121, 11922-11923.
10. Walsh, C. Nature, 2000, 406, 775-781.
11. Nikaido, H. J. Bacteriol., 1996, 178, 5853-5859.
12. Karlowsky, J. A.; Hoban, D. J.; Zelenitsky, S. A.; Zhanel, G. G. J. Antimicrob. Chemother., 1997, 40, 371-376.
13. Nelsestuen, G. L.; Martinez, M. B.; Flickinger, M.; Higgins, L.; Krick, T. Biochemistry, 2001, 40, 11965-11974
14. Walmsley, M. Trends Microbiol., 2001, 9, 71-79.
15. Nikaido, H. Curr. Opin. Microbiol., 1998, 1, 516-523.
16. Saier, M.H. Jr.; Paulsen, I.T.; Sliwinski, M.K.; Pao, S.S.; Skurray, R.A. and Nikaido, H. FASEB J., 1998, 12, 265-274.
17. Lewis, K. Curr. Boil., 1999, 9, R403-R407.
18. Pumbwe, L. and Piddock, L.J. Agents Chemother., 2000, 44, 2861-2864.
19. Putman, M.; van Veen, H.W.; Konings, W.N. Mol. Biol. Rev., 2000, 64, 672-693.
20. Herbert, P. and Schweizer, H.P. Genet. Mol. Res., 2003, 2, 48-62.
21. Brodersen, D. E.; Clemons, W. M.; Carter, A. P.; Wimberly, B. T.; Ramakrishnan, V. J. Mol. Biol., 2002, 316:725-768.
22. Carter, A. P.; Clemons, W. M.; Brodersen, D. E.; Morgan-Warren, R-J,; Wimberly, B. T.; Ramakrishnan, V. Nature, 2000, 407, 340-348.
23. Gill, A. E. and Amyes, S. G. J. Chemother., 2004, 16, 347-349.
24. Llano-Sotelo, B.; Azucena, E. F.; Kotra, L. P.; Mobashery, S.; Chow, C. S. Chem. Biol., 2002, 9, 455-463.
25. Shaw, K. J.; Rather, P. N.; Hare, R. S.; Miller, G. H. Microbiol. Rev., 1993, 57, 138-163.
26. Vanhoof, R.; Hannecart-Pokorni, E.; Content, J. Antimicrob. Agents Chemother., 1998, 42, 483-487.
27. McKay, G. A.; Roestamadji, J.; Mobashery, S.; Wright, G. D. Antimicrob Agents Chemother., 1996, 40, 2648-2650.
28. McKay, G. A.; Robinson, R. A.; Lane, W. S.; Wright, G. D. Biochemistry, 1994, 33, 14115-14120.
29. White, P. A.; McIver, C-J.; Rawlinson, W. D. Antimicrob. Agents Chemother., 2001, 45, 2658-2661.
30. Thompson, P. R.; Hughes, D. W.; Wright, G. W. Chem. Biol., 1996, 3, 747-755.
31. Siregar, J. J.; Lerner, S. A.; Mobashery, S. Antimicrob. Agents Chemother., 1994, 38, 641-647.
32. Hachler, H.; Santarnam, P.; Kayser, F.H. Antimicrob. Agents Chemother., 1996, 40, 1254-1256.
33. Burk, D. L.; Hon, W. C.; Leung, A. K.; Berghuis, A.M. Biochemistry, 2001, 40, 8756-8764.
34. Hon, W. C.; McKay, G. A.; Thompson, P. R.; Sweet, R. M.; Yang, D. S.; Wright, G. D.; Berghuis, A. M. Cell, 1997, 89, 887-895.
35. Noguchi, N.; Katayama, J.; O'Hara, K. FEMS Microbiol. Lett., 1996, 144, 197-202.
36. Roestamadji, J.; Grapsas, I.; Mobashery, S. J. Am. Chem. Soc., 1995, 117, 80-84.
37. Sucheck, S. J.; Wong, A. L.; Koeller, K. M.; Boehr, D. D.; Draker, K.; Sears, P.; Wright, G. D.; Wong, C. J. Am. Chem. Soc., 2000, 122, 5230-5231.
38. Hotta, K.; Sunada, A.; Ikeda, Y.; Kondo, S.J. Antibiot., 2000, 53, 1168-1174.
39. Chow, J. W.; Kak, V.; You, I.; Kao, S. J.; Petrin, J.; Clewell, D.B.; Lerner, S.A.; Miller, G. H. and Shaw, K. J. Antimicrob. Agents Chemother., 2001, 45, 2691-2697.
40. Costa, Y.; Galimand, M.; Leclercq, R.; Duval, J.; Courvalin, P. Antimicrob. Agents Chemother., 1993, 37, 1896-1903.
41. Franklin, K. and Clarke, A. J Antimicrob. Agents Chemother., 2001, 45, 2238-2244.
42. Hegde, S. S.; Javid-Majd, F.; Blanchard. J.S. J. Biol. Chem., 2001, 276, 45876-45881.
43. Aínsa, J. A.; Martin, C.; Gicquel, B.; Gomez-Lus, R. Antimicrob. Agents Chemother., 1996, 40, 2350-2355.
44. Wybenga-Groot, L. E.; Draker, K.; Wright, G. D.; Berghuis, A. M Structure Fold. Des., 1999, 7, 497-507.
45. Aínsa, J. A.; Pérez, E.; Pelicic, V.; Berthet, F-X.; Gicquel, B.; Martín, C. Mol. Microbiol., 1997, 24, 431-441.
46. Kotra, L. P.; Haddad, J.; Mobashery, S. Antimicrob. Agents Chemother., 2000, 44, 3249-3256.
47. Chow, J. W. Clin. Infect. Dis., 2000, 31, 586-589.
48. Wolf, E.; Vassilev, A.; Makino, Y.; Sali, A.; Nakatani, Y.; Burley, S. K. Cell, 1998, 94, 439-449.
49. Centron, D.; Roy, P. H. Antimicrob. Agents Chemother., 1998, 42, 1506-1508.
50. Bongaerts, G. P.; Molendijk, L. Antimicrob Agents Chemother., 1984, 25, 234-237.
51. Schmidt, F.; Niicken, R. J.; Renschke, R. B. Mol. Microbiol., 1988, 2, 709-717.
52. Ounissi, H.; Derlot, E.; Carlier, C.; Courvalin, P. Antimicrob. Agents Chemother., 1990, 34, 2164-2168.
53. Sakon, J.; Liao, H. H.; Kanikula, A. M.; Benning, M. M.; Rayment, I; Holden, H.M. Biochemistry, 1993, 32, 11977-11984.
54. Holm, L. and Sander, C. Trend. Boil. Chem., 1995, 20, 345-347.
55. Pedersen, L. C.; Benning, M. M,; Holden, H. M. Biochemistry, 1995, 35, 13305-13311.
56. Azucena, E.; Mobashery, S. Drug Resist Updat., 2001, 4, 106-117.
57. Roestamadji, J.; Mobashery, S. Bioorg Med Chem Lett., 1998, 8, 3483-3488.
58. McKay, G. A.; Wright, G. D. J. Biol. Chem., 1995, 270, 24686-24692.
59. Allen, N.E.; Alborn, W. E. Jr.; Hobbs, J. N. Jr.; Kirst, H. A. Antimicrob Agents Chemother., 1982, 22, 824-431.
60. Greenberg, W. A.; Priestley, E. S.; Sears, P. S.; Alper, P. B.; Rosenbohm, C.; Hendrix, M.; Hung, H-C.; Wong, C-H. J. Am. Chem. Soc., 1999, 121, 6527-6541.
61. McKay, G. A.; Roestamadji, J.; Mobashery, S.; Wright, G. D. Antimicrob Agents Chemother., 1996, 40, 2648-2650.
62. Allen, N.E.; Alborn, W. E. Jr.; Hobbs, J. N. Jr.; Kirst, H. A. Antimicrob Agents Chemother., 1982, 22, 824-831.
63. Yamaguchi, H.; Matsushita, M.; Nairn, A. C.; Kuriyan, J. Mol. Cell., 2001, 7, 1047-1057.
64. Roestamadji, J.; Grapsas, I.; Mobashery, S. J. Am. Chem. Soc., 1995, 117, 11060-11069.
65. Liu, M.; Haddad, J.; Azucena, E.; Kotra, L. P.; Kirzhner, M., Mobashery, S. J. Org. Chem., 2000, 65, 7422-7431.
66. Azucena, E.; Grapsas, I.; Mobashery, S. J. Am. Chem. Soc., 1997, 119, 2317-2318.
67. Daigle, D. M.; McKay, G. A.; Wright, G. D. J. Biol. Chem., 1997, 272, 24755-24758.
68. Burk, D. L.; Berghuis, A. M. Pharmacol. Ther., 2002, 93, 283-292.
69. Dove, A. 2002. Nat. Biotechnol., 2002, 20, 121-124.
70. Harth, G., P. C. Zamecnik, J. Y. Tang, D. Tabatadze, and M. A. Horwitz. Proc. Natl. Acad. Sci. USA., 2000, 97, 418-423.
71. Casin, I.; Hanau-Bercot, B.; Podglajen, I.; Vahaboglu, H.; Collatz, E. Antimicrob. Agents Chemother., 2003, 47, 697-703.
72. Torres, Viera.; Tsiodras, C.S.; Gold, H. S.; Coakley, E. P.; Wennersten, C.; Eliopoulos, G.M.; Moellering, R. C. Jr.; Inouye, R. T. Antimicrob. Agents Chemother., 2001, 45, 973-975.
73. White, D. G.; Maneewannakul, K.; von Hofe, E.; Zillman, M.; Eisenberg, W.; Field, A. K.; Levy, S. V. Antimicrob. Agents Chemother., 1997, 41, 2699-2704.
74. Good, L. and Nielsen, P.E. Nat. Biotechnol., 1998, 16, 355-358.
75. Sarno, R.; McGillivary, G.; Sherratt, D. J.; Actis, L. A.; Tolmasky, M. E. Antimicrob. Agents Chemother., 2002, 46, 3422-3427.
76. Kurreck, J. Eur. J. Biochem., 2003, 270, 1628-1644.
77. Wahlestedt, C. Trends Pharmacol. Sci., 1994, 15, 42-46.
78. Good, L.; Sandberg, R.; Larsson, O.; Nielsen, P. E.; Wahlestedt, C. Microbiology, 2000, 146, 2665-2670.
79. Eriksson, M.; Nielsen, P.E.; Good, L. J. Biol. Chem., 2002, 277, 7144-7147.