Overexpression and Mechanistic Analysis of Chromosomally Encoded Aminoglycoside 2′-N-Acetyltransferase (AAC(2′)-Ic) from Mycobacterium tuberculosis

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 45876-45881

  Hegde, Subray S ^c   Javid Majd, Farah ^a   Blanchard, John S ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; CLONING; ENZYMES; GENES; PROTEINS;

SUBSTRATE AFFINITY;

DISEASES;

ACETYL COENZYME A; ACYLTRANSFERASE; AMINOGLYCOSIDE; AMINOGLYCOSIDE 2' N ACETYLTRANSFERASE; AMINOGLYCOSIDE N ACETYLTRANSFERASE; ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE; PRIMER DNA;

AAC(2') IC GENE; ACETYLATION; ARTICLE; BACTERIAL GENE; BINDING AFFINITY; CHROMOSOME; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE EXPRESSION; GENE OVEREXPRESSION; MICHAELIS MENTEN KINETICS; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PURIFICATION; BACTERIAL CHROMOSOME; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

ACETYLTRANSFERASES; BASE SEQUENCE; CHROMOSOMES, BACTERIAL; CLONING, MOLECULAR; DNA PRIMERS; KINETICS; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; SUBSTRATE SPECIFICITY; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035824623     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108810200     Document Type: Article

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