Synthesis and cathepsin D inhibition of peptide-hydroxyethyl amine isosteres with cyclic tertiary amines

Letters in Peptide Science

Volumn 10, Issue 2, 2003, Pages 69-78

  McConnell, Rose M ^a   Godwin, Walter E ^a   Stefan, Amy ^a   Newton, Crystal ^a   Myers, Nikki ^a   Hatfield, Susan E ^b  

^a UNIVERSITY OF ARKANSAS   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Cathepsin d inhibitors; Hydroxyethylamine isosteres

Indexed keywords

3 (ACETYLALANYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (ACETYLALANYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 (ACETYLLEUCYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (ACETYLLEUCYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 (ACETYLVALYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (ACETYLVALYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 (CARBOBENZOXYALANYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (CARBOBENZOXYALANYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 (CARBOBENZOXYLEUCYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (CARBOBENZOXYLEUCYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 (CARBOBENZOXYVALYLPHENYLALANYLAMINO) 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 (CARBOBENZOXYVALYLPHENYLALANYLAMINO) 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 TERT BUTYLOXYCARBONYLAMINO 4 PHENYL 1 BUTENE; 3 TERT BUTYLOXYCARBONYLAMINO 4 PHENYL 1 N PIPERIDINE 2 BUTANOL; 3 TERT BUTYLOXYCARBONYLAMINO 4 PHENYL 1 N PYRROLIDINE 2 BUTANOL; 3 TERT BUTYLOXYCARBONYLAMINO 4 PHENYL 2 OXIRANE; ASPARTIC PROTEINASE; CATHEPSIN D; HEMOGLOBIN; PEPSTATIN; TERT BUTYLOXYCARBONYLPHENYLALANINAL; TERTIARY AMINE; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CANCER; CANCER RELAPSE; COLON CANCER; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROLYSIS; METASTASIS; OVARY CANCER; PROSTATE CANCER; PROTEIN FUNCTION; SYNTHESIS; UTERUS CANCER;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 18544367322     PISSN: 09295666     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:LIPS.0000032367.14994.e9     Document Type: Article

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