Analysis of the interaction of procathepsin D activation peptide with breast cancer cells

International Journal of Cancer

Volumn 73, Issue 3, 1997, Pages 403-409

  Vetvicka, Vaclav ^a   Vetvickova, Jana ^a   Hilgert, Ivan ^b   Voburka, Zdenek ^c   Fusek, Martin ^c  

^a University of Louisville School of Medicine   (United States)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BREAST CANCER; CANCER CELL; DRUG RECEPTOR BINDING; ENZYME INACTIVATION; GROWTH INHIBITION; MITOGENICITY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; STEM CELL; TUMOR GROWTH;

ANIMALS; ANTIBODIES; BREAST NEOPLASMS; CATHEPSIN D; CELL LINE; ENZYME ACTIVATION; ENZYME PRECURSORS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; RECEPTOR, IGF TYPE 2; RECEPTORS, GROWTH FACTOR;

EID: 0030663673     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19971104)73:3<403::AID-IJC15>3.0.CO;2-D     Document Type: Article

References (27)

1. CAPONY, F., ROUGEOT, C., MONTCOURRIER, P.H., CAVAILLÉS, V., SALAZAR, G. and ROCHEFORT, H., Increased secretion, altered processing and glycosylation of pro-cathepsin D in human mammary cancer cells. Cancer Res., 49, 3904-3909 (1989).
2. CAVAILLÉS, V., AUGEREAU, P. and ROCHEFORT, H., Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc. nat. Acad. Sci. (Wash.), 90, 203-207 (1993).
3. DENTON, G., SEKOWSKI, M. and PRICE, M.R., Induction of antibody responses to breast carcinoma associated mucins using synthetic peptide constructs as immunogens. Cancer Lett., 70, 143-150 (1993).
4. + lymphocyte subpopulation. J. Immunol., 154, 4294-4301 (1995).
5. FERRICK, D.A., SCHRENZEL, M.D., MULVANIA, T., HSIEH, B., FERLIN, W.G. and LEPPER, H., Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature (Lond.), 373, 255-257 (1995).
6. FUSEK, M. and VETVICKA, V., Mitogenic function of human procathepsin D-role of the activation peptide. Biochem. J., 303, 775-780 (1994).
7. GALTIER-DEREURE, F., CAPONY, F., MAUDELONDE, T. and ROCHEFORT, H., Estradiol stimulates cell growth and secretion of procathepsin D and 120-kilodalton protein in the human ovarian cancer cell line BG-1. J. Clin. Endocrinol. Metab., 75, 1497-1502 (1992).
8. GOLUMBEK, P.T., AZHARI, R., JAFFEE, E.M., LEVITSKY, H.I., LAZENBY, A., LEONG, K. and PARDOLL, D.M., Controlled release, biodegradable cytokine depots: a new approach in cancer vaccine design. Cancer Res., 53, 5841-5844 (1993).
9. GRASSEL, S. and HASILIK, A., Human cathepsin D precursor is associated with a 60 kDa glycosylated polypeptide. Biochem. biophys. Res. Comm., 182, 276-282 (1992).
10. HOFLACK, B. and KORNFELD, S., Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver. J. biol. Chem., 260, 12008-12014 (1985).
11. HSIUNG, L.M., BARCLAY, A.N., BRANDON, M.R., SIM, E. and PORTER, R.R., Purification of human C3b inactivator by monoclonal-antibody affinity chromatography. Biochem. J., 203, 293-298 (1982).
12. KOELSCH, G., METCALF, P., VETVICKA, V. and FUSEK, M., Human procathepsin D: three-dimensional model and isolation. In: K. Takahashi (ed.), Aspartic proteinases: structure, function, biology, and biomedical implications, pp. 273-278, New York, Plenum (1995).
13. KORNER, C., NURNBERG, B., UHDE, M. and BRAULKE, T., Mannose 6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins. J. biol. Chem., 270, 287-295 (1995).
14. KORNFELD, S. and MELLMAN, I., The biogenesis of lysosomes. Ann. Rev. Cell Biol., 5, 483-525 (1989).
15. LIAUDET, E., GARCIA, M. and ROCHEFORT, H., Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal. Oncogene, 9, 1145-1154 (1994).
16. MATHIEU, M., ROCHEFORT, H., BARENTON, B., PRÉBOIS, C. and VIGNON, F., Interactions of cathepsin-D and insulin-like growth fuctor-II (IGF-II) on the IGF-II/mannose-6-phosphate receptor in human breast cancer cells and possible consequences on mitogenic activity of IGF-II. Mol. Endocrinol., 4, 1327-1335 (1990).
17. METCALF, P. and FUSEK, M., Two crystal structures for cathepsin D: the lysosomal targeting signal and active site. EMBO J., 12, 1293-1302 (1993).
18. RIJNBOUT, S., AERTS, H.M.F.G., GEUZE, H.J., TAGER, J.M. and STROUS, G.J., Mannose-6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells. J. biol. Chem., 266, 4862-4868 (1991).
19. ROCHEFORT, H., Biological and clinical significance of cathepsin D in breast cancer. Acta Oncol., 31, 125-130 (1992).
20. STEIN, M., ZIJDERHAND-BLEEKEMOLEN, J.E., GEUZE, H., HASILIK, A. and VON FIGURA, K., Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes. EMBO J., 6, 2677-2681 (1987).
21. STEWART, A.J., PIGGOTT, N.H., MAY, F.E.B. and WESTLEY, B.R., Mitogenic activity of procathepsin D purified from conditioned medium of breast-cancer cells by affinity chromatography on pepstatinyl agarose. Int. J. Cancer, 57, 715-718 (1994).
22. STEWART, A.J., WESTLEY, B.R. and MAY, F.E.B., Modulation of the proliferative response of breast cancer cells to growth factors by estrogen. Brit. J. Cancer, 66, 640-648 (1992).
23. VETVICKA, V. and FUSEK, M., Activation of peripheral blood neutrophils and lymphocytes by human procathepsin D and insulin-like growth factor II. Cell. Immunol., 156, 332-341 (1994).
24. VETVICKA, V., VAGNER, J., BAUDYS, M., TANG, J., FOUNDLING, S.I. and FUSEK, M., Human breast milk contains procathepsin D - detection by specific antibodies. Biochem. mol. Biol. Int., 30, 921-928 (1993).
25. VETVICKA, V., VETVICKOVA, J. and FUSEK, M., Participation of the propetide on procathepsin D activation of human peripheral lymphocytes and neutrophils. Arch. Biochem. Biophys., 322, 295-298 (1995).
26. VIGNON, F., CAPONY, F., CHAMBON, M., FREISS, G., GARCIA, M. and ROCHEFORT, H., Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52 K protein. Endocrinology 118, 1537-1545 (1986).
27. WESTLEY, B. and ROCHEFORT, H., A secretion of glycoprotein induced by estrogens in human breast cancer cell lines. Cell, 20, 352-362 (1980).