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Volumn 41, Issue 13, 1998, Pages 2339-2344

Auxiliary agents for the peroral administration of peptide and protein drugs: Synthesis and evaluation of novel pepstatin analogues

Author keywords

[No Author keywords available]

Indexed keywords

AMINOALCOHOL; EPIDERMAL GROWTH FACTOR; HORSERADISH PEROXIDASE; PEPSIN A; PEPSTATIN DERIVATIVE; PEPTIDE DERIVATIVE; PROTEIN DERIVATIVE;

EID: 0032543525     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980015w     Document Type: Article
Times cited : (16)

References (13)
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    • The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins
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    • Bernkop-Schnürch, A. The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins. J. Control. Release, in press.
    • J. Control. Release
    • Bernkop-Schnürch, A.1
  • 2
    • 0030943636 scopus 로고    scopus 로고
    • Modified Mucoadhesive Polymers for the Peroral Administration of Mainly Elastase Degradable Therapeutic (Poly)peptides
    • Bernkop-Schnürch, A.; Schwarz, G. H.; Kratzel, M. Modified Mucoadhesive Polymers for the Peroral Administration of Mainly Elastase Degradable Therapeutic (Poly)peptides. J. Control. Release 1997, 47, 113-121.
    • (1997) J. Control. Release , vol.47 , pp. 113-121
    • Bernkop-Schnürch, A.1    Schwarz, G.H.2    Kratzel, M.3
  • 3
    • 0030813427 scopus 로고    scopus 로고
    • Development of a drug delivery system protecting from trypsinic degradation
    • Bernkop-Schnürch, A.; Bratengeyer, I.; Valenta, C. Development of a drug delivery system protecting from trypsinic degradation. Int. J. Pharm. 1997, 157, 17-25.
    • (1997) Int. J. Pharm. , vol.157 , pp. 17-25
    • Bernkop-Schnürch, A.1    Bratengeyer, I.2    Valenta, C.3
  • 4
    • 0028093189 scopus 로고
    • Solvent Isotope Effects on the Onset of Inhibition of Porcine Pepsin by Pepstatin
    • Cho, Y.-K.; Rebholz, K. L.; Northrop, D. B. Solvent Isotope Effects on the Onset of Inhibition of Porcine Pepsin by Pepstatin. Biochemistry 1994, 33, 9637-9642.
    • (1994) Biochemistry , vol.33 , pp. 9637-9642
    • Cho, Y.-K.1    Rebholz, K.L.2    Northrop, D.B.3
  • 5
    • 0028725018 scopus 로고
    • Gastric ulcer treatment with intravenous human epidermal growth factor: A double-blind controlled clinical study
    • Itoh, M.; Matsuo, Y. Gastric ulcer treatment with intravenous human epidermal growth factor: A double-blind controlled clinical study. J. Gastroenterol. Hepatol. 1994, 9, 78-83.
    • (1994) J. Gastroenterol. Hepatol. , vol.9 , pp. 78-83
    • Itoh, M.1    Matsuo, Y.2
  • 6
    • 0025272570 scopus 로고
    • Colloidal Bismuth Subcitrate Inhibits Peptic Degradation of Gastric Mucus and Epidermal Growth Factor in Vitro
    • Slomiany, B. L.; Nishikawa, H.; Bilski, J.; Slomiany, A. Colloidal Bismuth Subcitrate Inhibits Peptic Degradation of Gastric Mucus and Epidermal Growth Factor in Vitro. Am. J. Gastroenterol. 1990, 85, 390-393.
    • (1990) Am. J. Gastroenterol. , vol.85 , pp. 390-393
    • Slomiany, B.L.1    Nishikawa, H.2    Bilski, J.3    Slomiany, A.4
  • 7
    • 0030581134 scopus 로고    scopus 로고
    • Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation
    • Bernkop-Schnürch, A.; Dundalek, K. Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation. Int. J. Pharm. 1996, 138, 75-83.
    • (1996) Int. J. Pharm. , vol.138 , pp. 75-83
    • Bernkop-Schnürch, A.1    Dundalek, K.2
  • 8
    • 0028574816 scopus 로고
    • In vitro studies of gastric juice in patients with food-cobalamin mal absorption
    • Carmel, R. In vitro studies of gastric juice in patients with food-cobalamin mal absorption. Digest. Dis. Sci. 1994, 39, 2516-2522.
    • (1994) Digest. Dis. Sci. , vol.39 , pp. 2516-2522
    • Carmel, R.1
  • 9
    • 0027534406 scopus 로고
    • Evidence for the role of a cathepsin D-like activity in the release of gal β1-4 glcnac α2-6 sialyltransferase from rat and mouse 1 liver in whole-cell systems
    • McCaffrey, G.; Jamieson, J. C. Evidence for the role of a cathepsin D-like activity in the release of gal β1-4 glcnac α2-6 sialyltransferase from rat and mouse 1 liver in whole-cell systems. Comp. Biochem. Phys. C. 1993, 104, 91-94.
    • (1993) Comp. Biochem. Phys. C. , vol.104 , pp. 91-94
    • McCaffrey, G.1    Jamieson, J.C.2
  • 10
    • 0028111383 scopus 로고
    • Effects of phosphoramidon and pepstatin A on the secretion of endothelin-1 and big endothelin-1 by human umbilical vein endothelial cells-measurement by two-site enzyme-linked immunosorbent assays
    • Plumpton, C.; Kalinka, S.; Martin, R. C.; Horton, J. K.; Davenport, A. P. Effects of phosphoramidon and pepstatin A on the secretion of endothelin-1 and big endothelin-1 by human umbilical vein endothelial cells-measurement by two-site enzyme-linked immunosorbent assays. Clin. Sci. 1994, 87, 245-251.
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    • Plumpton, C.1    Kalinka, S.2    Martin, R.C.3    Horton, J.K.4    Davenport, A.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.