The role of the cytoskeleton during viral infection

Current Topics in Microbiology and Immunology

Volumn 285, Issue , 2004, Pages 67-108

  Dohner K ^a   Sodeik, B ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYTOSKELETON PROTEIN; DYNEIN ADENOSINE TRIPHOSPHATASE; ENZYME; KINESIN; MOLECULAR MOTOR; MYOSIN; NUCLEIC ACID; NUCLEOPROTEIN; VIRUS PROTEIN; VIRUS VECTOR;

ACTIN FILAMENT; ACTIVE TRANSPORT; ADENOVIRUS; BACULOVIRUS; BINDING AFFINITY; CELL BUDDING; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CELL ORGANELLE; CELL SURFACE; CHEMICAL ANALYSIS; CYTOPLASM; CYTOSKELETON; DIFFUSION; GENE THERAPY; HERPES VIRUS; INTERMEDIATE FILAMENT; INTRACELLULAR TRANSPORT; MEMBRANE TRANSPORT; MICROSCOPY; MICROTUBULE; MOLECULAR DYNAMICS; NERVE FIBER; NONHUMAN; PARVOVIRUS; POXVIRUS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN TRANSPORT; RETROGRADE NERVE FIBER TRANSPORT; RETROVIRUS; REVIEW; VACCINIA VIRUS; VIRION; VIROLOGY; VIRUS ADSORPTION; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS CORE; VIRUS INFECTION; VIRUS PARTICLE; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ANIMALS; CYTOSKELETAL PROTEINS; CYTOSKELETON; DNA VIRUS INFECTIONS; HUMANS; MICROTUBULES; MOLECULAR MOTOR PROTEINS; RNA VIRUS INFECTIONS; VIRAL PHYSIOLOGY;

ADENOVIRIDAE; BACULOVIRIDAE; HERPESVIRIDAE; PARVOVIRIDAE; PARVOVIRUS; POXVIRIDAE; UNIDENTIFIED BACULOVIRUS; UNIDENTIFIED RETROVIRUS; VACCINIA VIRUS;

EID: 1842862375     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (208)

1. Allan, V, Näthke, IS (2001) Catch and pull a microtubule: getting a grasp on the cortex. Nat Cell Biol 3:E226-8
2. Alonso, C, Miskin, J, Hernaez, B, Fernandez-Zapatero, P, Soto, L, Canto, C, Rodriguez-Crespo, I, Dixon, L, Escribano, JM (2001) African swine fever virus protein p54 interacts with the microtubular motor complex through direct binding to light-chain dynein. J Virol 75:9819-27
3. Aniento, F, Emans, N, Griffiths, G, Gruenberg, J (1993) Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol 123:1373-87
4. Avitabile, E, Di Gaeta, S, Torrisi, MR, Ward, PL, Roizman, B, Campadelli-Fiume, G (1995) Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis. J Virol 69:7472-82
5. Ayscough, K (1998) Use of latrunculin-A, an actin monomer-binding drug. Methods Enzymol 298:18-25
6. Bearer, EL, Breakefield, XO, Schuback, D, Reese, TS, LaVail, JH (2000) Retrograde axonal transport of herpes simplex virus: evidence for a single mechanism and a role for tegument. Proc Natl Acad Sci U S A 97:8146-50
7. Bowman, AB, Patel-King, RS, Benashski, SE, McCaffery, JM, Goldstein, LS, King, SM (1999) Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. J Cell Biol 146:165-80
8. Brown, SS (1999) Cooperation between microtubule- and actin-based motor proteins. Annu Rev Cell Dev Biol 15:63-80
9. Brunet, JP, Jourdan, N, Cotte-Laffitte, J, Linxe, C, Geniteau-Legendre, M, Servin, A, Quero, AM (2000) Rotavirus infection induces cytoskeleton disorganization in human intestinal epithelial cells: implication of an increase in intracellular calcium concentration. J Virol 74:10801-6
10. Bubb, MR, Senderowicz, AM, Sausville, EA, Duncan, KL, Korn, ED (1994) Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem 269:14869-71
11. Bukrinskaya, A, Brichacek, B, Mann, A, Stevenson, M (1998) Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton. J Exp Med 188:2113-25
12. Burkhardt, JK, Echeverri, CJ, Nilsson, T, Vallee, RB (1997) Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol 139:469-84
13. Ceccaldi, PE, Gillet, JP, Tsiang, H (1989) Inhibition of the transport of rabies virus in the central nervous system. J Neuropathol Exp Neurol 48:620-30
14. Charlton, CA, Volkman, LE (1993) Penetration of Autographa californica nuclear polyhedrosis virus nucleocapsids into IPLB Sf 21 cells induces actin cable formation. Virology 197:245-54
15. Chen, PH, Ornelles, DA, Shenk, T (1993) The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells. J Virol 67:3507-14
16. Cooper, JA (1987) Effects of cytochalasin and phalloidin on actin. J Cell Biol 105:1473-8
17. Coulombe, PA, Bousquet, O, Ma, L, Yamada, S, Wirtz, D (2000) The 'ins' and 'cuts' of intermediate filament organization. Trends Cell Biol 10:420-8
18. Coulombe, PA, Ma, L, Yamada, S, Wawersik, M (2001) Intermediate filaments at a glance. J Cell Sci 114:4345-7
19. Cramer, LP, Mitchison, TJ (1995) Myosin is involved in postmitotic cell spreading. J Cell Biol 131:179-89
20. Cudmore, S, Cossart, P, Griffiths, G, Way, M (1995) Actin-based motility of vaccinia virus. Nature 378:636-8
21. Cudmore, S, Reckmann, I, Way, M (1997) Viral manipulations of the actin cytoskeleton. Trends Microbiol 5:142-8
22. Dales, S, Chardonnet, Y (1973) Early events in the interaction of adenoviruses with HeLa cells. IV. Association with microtubules and the nuclear pore complex during vectorial movement of the inoculum. Virology 56:465-83
23. Deacon, SW, Serpinskaya, AS, Vaughan, PS, Fanarraga, ML, Vernos, I, Vaughan, KT, Gelfand, VI (2003) Dynactin is required for bidirectional organelle transport. J Cell Biol 160:297-301
24. Desai, A, Mitchison, TJ (1997) Microtubule polymerization dynamics. Annu Rev Cell Dev Biol 13:83-117
25. Desai, A, Verma, S, Mitchison, TJ, Walczak, CE (1999) Kin I kinesins are microtubule-destabilizing enzymes. Cell 96:69-78
26. Diefenbach, RJ, Miranda-Saksena, M, Diefenbach, E, Holland, DJ, Boadle, RA, Armati, PJ, Cunningham, AL (2002) Herpes simplex virus tegument protein US11 interacts with conventional kinesin heavy chain. J Virol 76:3282-3291
27. Digard, P, Elton, D, Bishop, K, Medcalf, E, Weeds, A, Pope, B (1999) Modulation of nuclear localization of the influenza virus nucleoprotein through interaction with actin filaments. J Virol 73:2222-31
28. Döhner, K, Wolfstein, A, Prank, U, Echeverri, C, Dujardin, D, Vallee, R, Sodeik, B (2002) Function of dynein and dynactin in herpes simplex virus capsid transport. Mol Biol Cell 13:2795-809
29. Doms, RW, Blumenthal, R, Moss, B (1990) Fusion of intra- and extracellular forms of vaccinia virus with the cell membrane. J Virol 64:4884-92
30. Downing, KH (2000) Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics. Annu Rev Cell Dev Biol 16:89-111
31. Dreschers, S, Roncarati, R, Knebel-Mörsdorf, D (2001) Actin rearrangement-inducing factor of baculoviruses is tyrosine phosphorylated and colocalizes to F-actin at the plasma membrane. J Virol 75:3771-8
32. Echeverri, CJ, Paschal, BM, Vaughan, KT, Vallee, RB (1996) Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol 132:617-33
33. Eckley, DM, Gill, SR, Melkonian, KA, Bingham, JB, Goodson, HV, Heuser, JE, Schroer, TA (1999) Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. J Cell Biol 147:307-20
34. Elliott, G, O'Hare, P (1997) Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 88:223-33
35. Elliott, G, O'Hare, P (1998) Herpes simplex virus type 1 tegument protein VP22 induces the stabilization and hyperacetylation of microtubules. J Virol 72:6448-55
36. Elliott, G, O'Hare, P (1999) Live-cell analysis of a green fluorescent protein-tagged herpes simplex virus infection. J Virol 73:4110-9
37. Espindola, FS, Suter, DM, Partata, LB, Cao, T, Wolenski, JS, Cheney, RE, King, SM, Mooseker, MS (2000) The light chain composition of chicken brain myosin-Va: calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN. Cell Motil Cytoskeleton 47:269-81
38. Fackler, OT, Luo, W, Geyer, M, Alberts, AS, Peterlin, BM (1999) Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol Cell 3:729-39
39. Fackler, OT, Peterlin, BM (2000) Endocytic entry of HIV-1. Curr Biol 10:1005-8
40. Ferreira, LR, Moussatche, N, Moura Neto, V (1994) Rearrangement of intermediate filament network of BHK-21 cells infected with vaccinia virus. Arch Virol 138:273-85
41. Forshey, BM, Aiken, C (2003) Disassembly of human immunodeficiency virus type 1 cores in vitro reveals association of Nef with the subviral ribonucleoprotein complex. J Virol 77:4409-14
42. Frischknecht, F, Moreau, V, Rottger, S, Gonfloni, S, Reckmann, I, Superti-Furga, G, Way, M (1999) Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling. Nature 401:926-9
43. Frischknecht, F, Way, M (2001) Surfing pathogens and the lessons learned for actin polymerization. Trends Cell Biol 11:30-38
44. Fuchs, E, Yang, Y (1999) Crossroads on cytoskeletal highways. Cell 98:547-50
45. Galigniana, MD, Radanyi, C, Renoir, JM, Housley, PR, Pratt, WB (2001) Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus. J Biol Chem 276:14884-9
46. Garcia-Mata, R, Bebok, Z, Sorscher, EJ, Sztul, ES (1999) Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. J Cell Biol 146:1239-54
47. Garoff, H, Hewson, R, Opstelten, DJ (1998) Virus maturation by budding. Microbiol Mol Biol Rev 62:1171-90
48. Geada, MM, Galindo, I, Lorenzo, MM, Perdiguero, B, Blasco, R (2001) Movements of vaccinia virus intracellular enveloped virions with GFP tagged to the F13L envelope protein. J Gen Virol 82:2747-60
49. Georgi, A, Mottola-Hartshorn, C, Warner, A, Fields, B, Chen, LB (1990) Detection of individual fluorescently labeled reovirions in living cells. Proc Natl Acad Sci U S A 87:6579-83
50. Giannakakou, P, Nakano, M, Nicolaou, KC, O'Brate, A, Yu, J, Blagosklonny, MV, Greber, UF, Fojo, T (2002) Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics. Proc Natl Acad Sci U S A 99:10855-60
51. Giannakakou, P, Sackett, DL, Ward, Y, Webster, KR, Blagosklonny, MV, Fojo, T (2000) p53 is associated with cellular microtubules and is transported to the nucleus by dynein. Nat Cell Biol 2:709-17
52. Glotzer, JB, Michou, AI, Baker, A, Saltik, M, Cotten, M (2001) Microtubule-independent motility and nuclear targeting of adenoviruses with fluorescently labeled genomes. J Virol 75:2421-34
53. Goldstein, LS, Yang, Z (2000) Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu Rev Neurosci 23:39-71
54. Goode, BL, Drubin, DG, Barnes, G (2000) Functional cooperation between the microtubule and actin cytoskeletons. Curr Opin Cell Biol 12:63-71
55. Greber, UF, Willetts, M, Webster, P, Helenius, A (1993) Stepwise dismantling of adenovirus 2 during entry into cells. Cell 75:477-86
56. Greene, WC, Peterlin, BM (2002) Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med 8:673-80
57. Gupta, S, De, BP, Drazba, JA, Banerjee, AK (1998) Involvement of actin microfilaments in the replication of human parainfluenza virus type 3. J Virol 72:2655-62
58. Gurland, G, Gundersen, GG (1995) Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts. J Cell Biol 131:1275-90
59. Hanlon, DW, Yang, Z, Goldstein, LS (1997) Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron 18:439-51
60. Heath, CM, Windsor, M, Wileman, T (2001) Aggresomes resemble sites specialized for virus assembly. J Cell Biol 153:449-55
61. Herrmann, C, Wray, J, Travers, F, Barman, T (1992) Effect of 2,3-butanedione monoxime on myosin and myofibrillar ATPases. An example of an uncompetitive inhibitor. Biochemistry 31:12227-32
62. Hirokawa, N, Takemura, R. (2003). Kinesin superfamily proteins. In Molecular Motors (M. Schliwa, ed.), pp. 79-109. Wiley-VCH Verlag, Weinheim
63. Hofmann, W, Reichart, B, Ewald, A, Muller, E, Schmitt, I, Stauber, RH, Lottspeich, F, Jockusch, BM, Scheer, U, Hauber, J, Dabauvalle, MC (2001) Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin. J Cell Biol 152:895-910
64. Hogle, JM (2002) Poliovirus cell entry: common structural themes in viral cell entry pathways. Annu Rev Microbiol 56:677-702
65. Holland, DJ, Miranda-Saksena, M, Boadle, RA, Armati, P, Cunningham, AL (1999) Anterograde transport of herpes simplex virus proteins in axons of peripheral human fetal neurons: an immunoelectron microscopy study. J Virol 73:8503-11
66. Holleran, EA, Karki, S, Holzbaur, EL (1998) The role of the dynactin complex in intracellular motility. Int Rev Cytol 182:69-109
67. Hollinshead, M, Rodger, G, Van Eijl, H, Law, M, Hollinshead, R, Vaux, DJ, Smith, GL (2001) Vaccinia virus utilizes microtubules for movement to the cell surface. J Cell Biol 154:389-402
68. Howard, J, Hyman, AA (2003) Dynamics and mechanics of the microtubule plus end. Nature 422:753-8
69. Hunter, AW, Caplow, M, Coy, DL, Hancock, WO, Diez, S, Wordeman, L, Howard, J (2003) The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol Cell 11:445-57
70. Igakura, T, Stinchcombe, JC, Goon, PK, Taylor, GP, Weber, JN, Griffiths, GM, Tanaka, Y, Osame, M, Bangham, CR (2003) Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. Science 299:1713-6
71. Iyengar, S, Hildreth, JE, Schwartz, DH (1998) Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells. J Virol 72:5251-5
72. Jacob, Y, Badrane, H, Ceccaldi, PE, Tordo, N (2000) Cytoplasmic dynein LC8 interacts with lyssavirus phosphoprotein. J Virol 74:10217-22
73. Jaffrey, SR, Snyder, SH (1996) PIN: an associated protein inhibitor of neuronal nitric oxide synthase. Science 274:774-7
74. Jimbo, T, Kawasaki, Y, Koyama, R, Sato, R, Takada, S, Haraguchi, K, Akiyama, T (2002) Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol 4:323-7
75. Jordan, MA, Wilson, L (1999) The use and action of drugs in analyzing mitosis. Methods Cell Biol 61:267-95
76. Karcher, RL, Deacon, SW, Gelfand, VI (2002) Motor-cargo interactions: the key to transport specificity. Trends Cell Biol 12:21-7
77. Karki, S, Holzbaur, EL (1999) Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol 11:45-53
78. Kasman, LM, Volkman, LE (2000) Filamentous actin is required for lepidopteran nucleopolyhedrovirus progeny production. J Gen Virol 81:1881-8
79. Keating, TJ, Borisy, GG (1999) Centrosomal and non-centrosomal microtubules. Biol Cell 91:321-9
80. Kieke, MC, Titus, MA. (2003). The myosin superfamily: An overview. In Molecular Motors (M. Schliwa, ed.), pp. 3-44. Wiley-VCH Verlag, Weinheim
81. Kim, W, Tang, Y, Okada, Y, Torrey, TA, Chattopadhyay, SK, Pfleiderer, M, Falkner, FG, Dorner, F, Choi, W, Hirokawa, N, Morse, HC, 3rd (1998) Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein. J Virol 72:6898-901
82. Kimura, T, Hashimoto, I, Yamamoto, A, Nishikawa, M, Fujisawa, JI (2000) Rev-dependent association of the intron-containing HIV-1 gag mRNA with the nuclear actin bundles and the inhibition of its nucleocytoplasmic transport by latrunculin-B. Genes Cells 5:289-307
83. King, SM (2000) AAA domains and organization of the dynein motor unit. J Cell Sci 113:2521-6
84. King, SM. (2003). Dynein motors: Structure, mechanochemistry and regulation. In Molecular Motors (M. Schliwa, ed.), pp. 45-78. Wiley-VCH Verlag, Weinheim
85. Klupp, BG, Granzow, H, Mettenleiter, TC (2000) Primary envelopment of pseudorabies virus at the nuclear membrane requires the UL34 gene product. J Virol 74:10063-73
86. Kopito, RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10:524-30
87. Kotsakis, A, Pomeranz, LE, Blouin, A, Blaho, JA (2001) Microtubule reorganization during herpes simplex virus type 1 infection facilitates the nuclear localization of VP22, a major virion tegument protein. J Virol 75:8697-711
88. Krijnse Locker, J, Kuehn, A, Schleich, S, Rutter, G, Hohenberg, H, Wepf, R, Griffiths, G (2000) Entry of the two infectious forms of vaccinia virus at the plasma membrane is signaling-dependent for the IMV but not the EEV. Mol Biol Cell 11:2497-511
89. Kristensson, K, Lycke, E, Roytta, M, Svennerholm, B, Vahlne, A (1986) Neuritic transport of herpes simplex virus in rat sensory neurons in vitro. Effects of substances interacting with microtubular function and axonal flow [nocodazole, taxol and erythro-9-3-(2-hydroxynonyl)adenine]. J Gen Virol 67:2023-8
90. Lanier, LM, Volkman, LE (1998) Actin binding and nucleation by Autographa californica M nucleopolyhedrovirus. Virology 243:167-77
91. Leopold, PL, Ferris, B, Grinberg, I, Worgall, S, Hackett, NR, Crystal, RG (1998) Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther 9:367-78
92. Leopold, PL, Kreitzer, G, Miyazawa, N, Rempel, S, Pfister, KK, Rodriguez-Boulan, E, Crystal, RG (2000) Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther 11:151-65
93. Leung, CL, Green, KJ, Liem, RK (2002) Plakins: a family of versatile cytolinker proteins. Trends Cell Biol 12:37-45
94. Lippincott-Schwartz, J, Roberts, TH, Hirschberg, K (2000) Secretory protein trafficking and organelle dynamics in living cells. Annu Rev Cell Dev Biol 16:557-89
95. Liu, B, Dai, R, Tian, CJ, Dawson, L, Gorelick, R, Yu, XF (1999) Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin. J Virol 73:2901-8
96. Lo, KW, Naisbitt, S, Fan, JS, Sheng, M, Zhang, M (2001) The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif. J Biol Chem 276:14059-66
97. Luby-Phelps, K (2000) Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int Rev Cytol 192:189-221
98. Luftig, RB, Lupo, LD (1994) Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases. Trends Microbiol 2:178-82
99. Luftig, RB, Weihing, RR (1975) Adenovirus binds to rat brain microtubules in vitro. J Virol 16:696-706
100. Lukashok, SA, Tarassishin, L, Li, Y, Horwitz, MS (2000) An adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis complexes with dynein and a small GTPase. J Virol 74:4705-9
101. Lycke, E, Hamark, B, Johansson, M, Krotochwil, A, Lycke, J, Svennerholm, B (1988) Herpes simplex virus infection of the human sensory neuron. An electron microscopy study. Arch Virol 101:87-104
102. Mabit, H, Nakano, MY, Prank, U, Saam, B, Donner, K, Sodeik, B, Greber, UF (2002) Intact microtubules support adenovirus and herpes simplex virus infections. J Virol 76:9962-71
103. Machesky, LM, Insall, RH, Volkman, LE (2001) WASP homology sequences in baculoviruses. Trends Cell Biol 11:286-7
104. Mallardo, M, Schleich, S, Krijnse Locker, J (2001) Microtubule-dependent organization of vaccinia virus core-derived early mRNAs into distinct cytoplasmic structures. Mol Biol Cell 12:3875-91
105. Marsh, M, Bron, R (1997) SFV infection in CHO cells: cell-type specific restrictions to productive virus entry at the cell surface. J Cell Sci 110:95-103
106. Martin, A, O'Hare, P, McLauchlan, J, Elliott, G (2002) Herpes simplex virus tegument protein VP22 contains overlapping domains for cytoplasmic localization, microtubule interaction, and chromatin binding. J Virol 76:4961-70
107. Martinez-Moreno, M, Navarro-Lerida, I, Roncal, F, Albar, JP, Alonso, C, Gavilanes, F, Rodriguez-Crespo, I (2003) Recognition of novel viral sequences that associate with the dynein light chain LC8 identified through a pepscan technique. FEBS Lett 544:262-267
108. McDonald, D, Vodicka, MA, Lucero, G, Svitkina, TM, Borisy, GG, Emerman, M, Hope, TJ (2002) Visualization of the intracellular behavior of HIV in living cells. J Cell Biol 159:441-52
109. Mebatsion, T (2001) Extensive attenuation of rabies virus by simultaneously modifying the dynein light chain binding site in the P protein and replacing Arg333 in the G protein. J Virol 75:11496-502
110. Merdes, A, Cleveland, DW (1997) Pathways of spindle pole formation: different mechanisms; conserved components. J Cell Biol 138:953-6
111. Mery, PF, Pavoine, C, Pecker, F, Fischmeister, R (1995) Erythro-9-(2-hydroxy-3-non-yl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes. Mol Pharmacol 48:121-30
112. Mettenleiter, TC (2002) Herpesvirus assembly and egress. J Virol 76:1537-47
113. Miles, BD, Luftig, RB, Weatherbee, JA, Weihing, RR, Weber, J (1980) Quantitation of the interaction between adenovirus types 2 and 5 and microtubules inside infected cells. Virology 105:265-9
114. Miller, N, Hutt-Fletcher, LM (1992) Epstein-Barr virus enters B cells and epithelial cells by different routes. J Virol 66:3409-14
115. Miranda-Saksena, M, Armati, P, Boadle, RA, Holland, DJ, Cunningham, AL (2000) Anterograde transport of herpes simplex virus type 1 in cultured, dissociated human and rat dorsal root ganglion neurons. J Virol 74:1827-39
116. Mitchison, T, Kirschner, M (1984) Dynamic instability of microtubule growth. Nature 312:237-42
117. Mojon, D, Zhang, W, Oetliker, H (1993) Inhibition by 2,3-butanedione- monoxime of mitochondrial ADP-dependent respiration and muscle contraction. Biochem Mol Biol Int 31:501-7
118. Moreau, V, Frischknecht, F, Reckmann, I, Vincentelli, R, Rabut, G, Stewart, D, Way, M (2000) A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization. Nat Cell Biol 2:441-8
119. Mouland, AJ, Xu, H, Cui, H, Krueger, W, Munro, TP, Prasol, M, Mercier, J, Rekosh, D, Smith, R, Barbarese, E, Cohen, EA, Carson, JH (2001) RNA trafficking signals in human immunodeficiency virus type 1. Mol Cell Biol 21:2133-43
120. Mueller, S, Cao, X, Welker, R, Wimmer, E (2002) Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis. J Biol Chem 277:7897-904
121. Nakanishi, S, Kakita, S, Takahashi, I, Kawahara, K, Tsukuda, E, Sano, T, Yamada, K, Yoshida, M, Kase, H, Matsuda, Y, et al. (1992) Wortmannin, a microbial product inhibitor of myosin light chain kinase. J Biol Chem 267:2157-63
122. Nakanishi, S, Yamada, K, Iwahashi, K, Kuroda, K, Kase, H (1990) KT5926, a potent and selective inhibitor of myosin light chain kinase. Mol Pharmacol 37:482-8
123. Nangaku, M, Sato-Yoshitake, R, Okada, Y, Noda, Y, Takemura, R, Yamazaki, H, Hirokawa, N (1994) KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79:1209-20
124. Nicola, AV, McEvoy, AM, Straus, SE (2003) Roles for endocytosis and low pH in herpes simplex virus entry into HeLa and Chinese hamster ovary cells. J Virol 77:5324-32
125. Noda, Y, Okada, Y, Saito, N, Setou, M, Xu, Y, Zhang, Z, Hirokawa, N (2001) KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes. J Cell Biol 155:77-88
126. Nurminsky, DI, Nurminskaya, MV, Benevolenskaya, EV, Shevelyov, YY, Hartl, DL, Gvozdev, VA (1998) Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing. Mol Cell Biol 18:6816-25
127. Ohara, PT, Chin, MS, LaVail, JH (2000) The spread of herpes simplex virus type 1 from trigeminal neurons to the murine cornea: an immunoelectron microscopy study. J Virol 74:4776-86
128. Ohkawa, T, Rowe, AR, Volkman, LE (2002) Identification of six Autographa californica multicapsid nucleopolyhedrovirus early genes that mediate nuclear localization of G-actin. J Virol 76:12281-9
129. Ohkawa, T, Volkman, LE (1999) Nuclear F-actin is required for AcMNPV nucleocapsid morphogenesis. Virology 264:1-4
130. Ojala, PM, Sodeik, B, Ebersold, MW, Kutay, U, Helenius, A (2000) Herpes simplex virus type 1 entry into host cells: reconstitution of capsid binding and uncoating at the nuclear pore complex in vitro. Mol Cell Biol 20:4922-31
131. Okada, Y, Yamazaki, H, Sekine-Aizawa, Y, Hirokawa, N (1995) The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81:769-80
132. Ott, DE, Coren, LV, Kane, BP, Busch, LK, Johnson, DG, Sowder, RC, 2nd, Chertova, EN, Arthur, LO, Henderson, LE (1996) Cytoskeletal proteins inside human immunodeficiency virus type 1 virions. J Virol 70:7734-43
133. Payne, LG, Norrby, E (1978) Adsorption and penetration of enveloped and naked vaccinia virus particles. J Virol 27:19-27
134. Pederson, T, Aebi, U (2002) Actin in the nucleus: what form and what for? J Struct Biol 140:3-9
135. Penfold, ME, Armati, P, Cunningham, AL (1994) Axonal transport of herpes simplex virions to epidermal cells: evidence for a specialized mode of virus transport and assembly. Proc Natl Acad Sci U S A 91:6529-33
136. Penningroth, SM (1986) Erythro-9-[3-(2-hydroxynonyl)]adenine and vanadate as probes for microtubule-based cytoskeletal mechanochemistry. Methods Enzymol 134:477-87
137. Peretti, D, Peris, L, Rosso, S, Quiroga, S, Caceres, A (2000) Evidence for the involvement of KIF4 in the anterograde transport of L1-containing vesicles. J Cell Biol 149:141-52
138. Phillips, RM, Altschuld, RA (1996) 2,3-Butanedione 2-monoxime (BDM) induces calcium release from canine cardiac sarcoplasmic reticulum. Biochem Biophys Res Commun 229:154-7
139. Ploubidou, A, Moreau, V, Ashman, K, Reckmann, I, Gonzalez, C, Way, M (2000) Vaccinia virus infection disrupts microtubule organization and centrosome function. EMBO J 19:3932-44
140. Ploubidou, A, Way, M (2001) Viral transport and the cytoskeleton. Curr Opin Cell Biol 13:97-105
141. Poisson, N, Real, E, Gaudin, Y, Vaney, MC, King, S, Jacob, Y, Tordo, N, Blondel, D (2001) Molecular basis for the interaction between rabies virus phosphoprotein P and the dynein light chain LC8: dissociation of dynein-binding properties and transcriptional functionality of P. J Gen Virol 82:2691-6
142. Rando, OJ, Zhao, K, Crabtree, GR (2000) Searching for a function for nuclear actin. Trends Cell Biol 10:92-7
143. Raux, H, Flamand, A, Blondel, D (2000) Interaction of the rabies virus P protein with the LC8 dynein light chain. J Virol 74:10212-6
144. Reynolds, AE, Wills, EG, Roller, RJ, Ryckman, BJ, Baines, JD (2002) Ultrastructural localization of the herpes simplex virus type 1 UL31, UL34, and US3 proteins suggests specific roles in primary envelopment and egress of nucleocapsids. J Virol 76:8939-52
145. Richard de Soultrait, V, Caumont, A, Durrens, P, Calmels, C, Parissi, V, Recordon, P, Bon, E, Desjobert, C, Tarrago-Litvak, L, Fournier, M (2002) HIV-1 integrase interacts with yeast microtubule-associated proteins. Biochim Biophys Acta 1575:40-8
146. Rietdorf, J, Ploubidou, A, Reckmann, I, Holmstrom, A, Frischknecht, F, Zettl, M, Zimmermann, T, Way, M (2001) Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus. Nat Cell Biol 3:992-1000
147. Rodriguez-Crespo, I, Yelamos, B, Roncal, F, Albar, JP, Ortiz de Montellano, PR, Gavilanes, F (2001) Identification of novel cellular proteins that bind to the LC8 dynein light chain using a pepscan technique. FEBS Lett 503:135-41
148. Roizman, B, Knipe, DM. (2001). Herpes simplex viruses and their replication. In Fundamental Virology (D. M. Knipe and P. M. Howley, eds.), pp. 1123-1183. Lippincott Williams & Wilkins, Philadelphia
149. Roncarati, R, Knebel-Mörsdorf, D (1997) Identification of the early actin-rearrangement-inducing factor gene, arif-1, from Autographa californica multicapsid nuclear polyhedrosis virus. J Virol 71:7933-41
150. Ruchhoeft, ML, Harris, WA (1997) Myosin functions in Xenopus retinal ganglion cell growth cone motility in vivo. J Neurobiol 32:567-78
151. Saib, A, Puvion-Dutilleul, F, Schmid, M, Peries, J, de The, H (1997) Nuclear targeting of incoming human foamy virus Gag proteins involves a centriolar step. J Virol 71:1155-61
152. Saito, N, Okada, Y, Noda, Y, Kinoshita, Y, Kondo, S, Hirokawa, N (1997) KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron 18:425-38
153. Sakowicz, R, Berdelis, MS, Ray, K, Blackburn, CL, Hopmann, C, Faulkner, DJ, Goldstein, LS (1998) A marine natural product inhibitor of kinesin motors. Science 280:292-5
154. Sanderson, CM, Hollinshead, M, Smith, GL (2000) The vaccinia virus A27L protein is needed for the microtubule-dependent transport of intracellular mature virus particles. J Gen Virol 81 Pt 1:47-58
155. Sanderson, CM, Way, M, Smith, GL (1998) Virus-induced cell motility. J Virol 72:1235-43
156. Sanlioglu, S, Benson, PK, Yang, J, Atkinson, EM, Reynolds, T, Engelhardt, JF (2000) Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation. J Virol 74:9184-96
157. Sasaki, H, Nakamura, M, Ohno, T, Matsuda, Y, Yuda, Y, Nonomura, Y (1995) Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells. Proc Natl Acad Sci U S A 92:2026-30
158. Scaplehorn, N, Holmstrom, A, Moreau, V, Frischknecht, F, Reckmann, I, Way, M (2002) Grb2 and Nek act cooperatively to promote actin-based motility of vaccinia virus. Curr Biol 12:740-5
159. Schaeffer, E, Geleziunas, R, Greene, WC (2001) Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J Virol 75:2993-3000
160. + current in human T lymphocytes. J Pharmacol Exp Ther 261:438-46
161. Schliwa, M, Woehlke, G (2003) Molecular motors. Nature 422:759-65
162. Schnapp, BJ (2003) Trafficking of signaling modules by kinesin motors. J Cell Sci 116:2125-35
163. Seisenberger, G, Ried, MU, Endress, T, Buning, H, Hallek, M, Brauchle, C (2001) Real-time single-molecule imaging of the infection pathway of an adeno-associated virus. Science 294:1929-32
164. Shah, JV, Flanagan, LA, Janmey, PA, Leterrier, JF (2000) Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin. Mol Biol Cell 11:3495-508
165. Sharp, DJ, Rogers, GC, Scholey, JM (2000) Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos. Nat Cell Biol 2:922-30
166. Shenk, T. (2001). Adenoviridae: The viruses and their replication. In Fundamental Virology (D. M. Knipe and P. M. Howley, eds.), pp. 1053-1088. Lippincott Williams & Wilkins, Philadelphia
167. Skepper, JN, Whiteley, A, Browne, H, Minson, A (2001) Herpes simplex virus nucleocapsids mature to progeny virions by an envelopment→ deenvelopment→reentoreenvelopmentpathway. J Virol 75: 5697 - - 702
168. Smith, GA, Enquist, LW (2002) Break ins and break outs: Viral interactions with the cytoskeleton of mammalian cells. Annu Rev Cell Dev Biol 18:135-61
169. Smith, GA, Gross, SP, Enquist, LW (2001) Herpesviruses use bidirectional fast-axonal transport to spread in sensory neurons. Proc Natl Acad Sci U S A 98:3466-70
170. Smith, GL, Vanderplasschen, A, Law, M (2002) The formation and function of extracellular enveloped vaccinia virus. J Gen Virol 83:2915-31
171. Sodeik, B (2000) Mechanisms of viral transport in the cytoplasm. Trends Microbiol 8:465-72
172. Sodeik, B (2002) Unchain my heart, baby let me go-the entry and intracellular transport of HIV. J Cell Biol 159:393-5
173. Sodeik, B, Doms, RW, Ericsson, M, Hiller, G, Machamer, CE, van't Hof, W, van Meer, G, Moss, B, Griffiths, G (1993) Assembly of vaccinia virus: role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks. J Cell Biol 121:521-41
174. Sodeik, B, Ebersold, MW, Helenius, A (1997) Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J Cell Biol 136:1007-21
175. Sodeik, B, Krijnse-Locker, J (2002) Assembly of vaccinia virus revisited: de novo membrane synthesis or acquisition from the host? Trends Microbiol 10:15-24
176. Suikkanen, S, Aaltonen, T, Nevalainen, M, Välilehto, O, Lindholm, L, Vuento, M, Vihinen-Ranta, M (2003) Exploitation of microtubule cytoskeleton and dynein during parvoviral traffic towards the nucleus. J Virol 77:10270-9
177. Suikkanen, S, Saajarvi, K, Hirsimaki, J, Valilehto, O, Reunanen, H, Vihinen-Ranta, M, Vuento, M (2002) Role of recycling endosomes and lysosomes in dynein-dependent entry of canine parvovirus. J Virol 76:4401-11
178. Suomalainen, M, Nakano, MY, Boucke, K, Keller, S, Greber, UF (2001) Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus. EMBO J 20:1310-9
179. Suomalainen, M, Nakano, MY, Keller, S, Boucke, K, Stidwill, RP, Greber, UF (1999) Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus. J Cell Biol 144:657-72
180. Susalka, SJ, Nikulina, K, Salata, MW, Vaughan, PS, King, SM, Vaughan, KT, Pfister, KK (2002) The roadblock light chain binds a novel region of the cytoplasmic dynein intermediate chain. J Biol Chem 277:32939-46
181. Tai, AW, Chuang, JZ, Sung, CH (2001) Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport. J Cell Biol 153:1499-510
182. Takeda, S, Yamazaki, H, Seog, DH, Kanai, Y, Terada, S, Hirokawa, N (2000)
183. Tang, Q, Staub, CM, Gao, G, Jin, Q, Wang, Z, Ding, W, Aurigemma, RE, Mulder, KM (2002) A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell 13:4484-96
184. Tang, Y, Winkler, U, Freed, EO, Torrey, TA, Kim, W, Li, H, Goff, SP, Morse, HC, 3rd (1999) Cellular motor protein KIF-4 associates with retroviral Gag. J Virol 73: 10508-13
185. Tekotte, H, Davis, I (2002) Intracellular mRNA localization: motors move messages. Trends Genet 18:636-42
186. Tolonen, N, Doglio, L, Schleich, S, Krijnse Locker, J (2001) Vaccinia virus DNA replication occurs in endoplasmic reticulum-enclosed cytoplasmic mini-nuclei. Mol Biol Cell 12:2031-46
187. Tomishima, MJ, Enquist, LW (2001) A conserved α-herpesvirus protein necessary for axonal localization of viral membrane proteins. J Cell Biol 154:741-752
188. Topp, KS, Bisla, K, Saks, ND, Lavail, JH (1996) Centripetal transport of herpes simplex virus in human retinal pigment epithelial cells in vitro. Neuroscience 71:1133-44
189. Topp, KS, Meade, LB, LaVail, JH (1994) Microtubule polarity in the peripheral processes of trigeminal ganglion cells: relevance for the retrograde transport of herpes simplex virus. J Neurosci 14:318-25
190. Trotman, LC, Mosberger, N, Fornerod, M, Stidwill, RP, Greber, UF (2001) Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1. Nat Cell Biol 3:1092-100
191. Tsiang, H, Ceccaldi, PE, Lycke, E (1991) Rabies virus infection and transport in human sensory dorsal root ganglia neurons. J Gen Virol 72:1191-4
192. Valetti, C, Wetzel, DM, Schrader, M, Hasbani, MJ, Gill, SR, Kreis, TE, Schroer, TA (1999) Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol Biol Cell 10:4107-20
193. van Eijl, H, Hollinshead, M, Rodger, G, Zhang, WH, Smith, GL (2002) The vaccinia virus F12L protein is associated with intracellular enveloped virus particles and is required for their egress to the cell surface. J Gen Virol 83:195-207
194. van Leeuwen, H, Elliott, G, O'Hare, P (2002) Evidence of a role for nonmuscle myosin II in herpes simplex virus type 1 egress. J Virol 76:3471-81
195. van Loo, ND, Fortunati, E, Ehlert, E, Rabelink, M, Grosveld, F, Scholte, BJ (2001) Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. J Virol 75:961-70
196. Vanderplasschen, A, Hollinshead, M, Smith, GL (1998) Intracellular and extracellular vaccinia virions enter cells by different mechanisms. J Gen Virol 79:877-87
197. Verhey, KJ. (2003). Motors and membrane trafficking. In Molecular Motors (M. Schliwa, ed.), pp. 377-409. Wiley-VCH Verlag, Weinheim
198. Ward, BM, Moss, B (2001) Vaccinia virus intracellular movement is associated with microtubules and independent of actin tails. J Virol 75:11651-63
199. Welch, MD, Mullins, RD (2002) Cellular control of actin nucleation. Annu Rev Cell Dev Biol 18:247-88
200. Wilk, T, Gowen, B, Fuller, SD (1999) Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein. J Virol 73:1931-40
201. Willard, M (2002) Rapid directional translocations in virus replication. J Virol 76:5220-5232
202. Xu, Y, Takeda, S, Nakata, T, Noda, Y, Tanaka, Y, Hirokawa, N (2002) Role of KIFC3 motor protein in Golgi positioning and integration. J Cell Biol 158:293-303
203. Ye, GJ, Vaughan, KT, Vallee, RB, Roizman, B (2000) The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol 74:1355-63
204. Young, A, Dictenberg, JB, Purohit, A, Tuft, R, Doxsey, SJ (2000) Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes. Mol Biol Cell 11:2047-56
205. Zhang, J, Campbell, RE, Ting, AY, Tsien, RY (2002) Creating new fluorescent probes for cell biology. Nat Rev Mol Cell Biol 3:906-18
206. Zhou, ZH, Chen, DH, Jakana, J, Rixon, FJ, Chiu, W (1999) Visualization of tegument-capsid interactions and DNA in intact herpes simplex virus type 1 virions. J Virol 73:3210-8
207. Ziegelbauer, J, Shan, B, Yager, D, Larabell, C, Hoffmann, B, Tjian, R (2001) Transcription factor MIZ-1 is regulated via microtubule association. Mol Cell 8:339-49
208. Zigmond, SH (1993) Recent quantitative studies of actin filament turnover during cell locomotion. Cell Motil Cytoskeleton 25:309-16