The spread of herpes simplex virus type 1 from trigeminal neurons to the murine cornea: An immunoelectron microscopy study

Journal of Virology

Volumn 74, Issue 10, 2000, Pages 4776-4786

  Ohara, Peter T ^a,b   Chin, Marian S ^a,c   Lavail, Jennifer H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; CELL SURFACE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA STROMA; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; IMMUNOCYTOCHEMISTRY; IMMUNOELECTRON MICROSCOPY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL; TRIGEMINAL NERVE; TRIGEMINUS GANGLION;

ANIMALS; DISEASE MODELS, ANIMAL; EPITHELIUM, CORNEAL; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNOHISTOCHEMISTRY; KERATITIS, HERPETIC; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, IMMUNOELECTRON; NEURONS, AFFERENT; TRIGEMINAL GANGLION;

EID: 0033997113     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.10.4776-4786.2000     Document Type: Article

References (30)

1. Courtoy, P. J., D. H. Picton, and M. G. Farquhar. 1983. Resolution and limitations of the immunoperoxidase procedure in the localization of extracellular antigens. J. Histochem. Cytochem. 31:945-951.
2. Crouse, C. A., S. C. Pflugfelder, I. Pereira, T. Cleary, S. Rabinowitz, and S. S. Atherton. 1990. Detection of herpesviral genomes in normal and diseased corneal epithelium. Curr. Eye Res. 9:569-581.
3. Gipson, I. K., and S. P. Sugrue. 1994. Cell biology of the corneal epithelium, p. 1-13. In D. M. Albert and F. A. Jakobiec (ed.), Principles and practice of ophthalmology. Lippincott, Philadelphia, Pa.
4. Harris, L., and D. Purves. 1989. Rapid remodeling of sensory endings in the corneas of living mice. J. Neurosci. 9:2210-2214.
5. Hayashi, K. 1995. Role of tight junctions of polarized epithelial MDCK cells in the replication of herpes simplex virus type 1. J. Med. Virol. 47:323-329.
6. Holland, D. J., M. Miranda-Saksena, R. A. Boadle, P. Armati, and A. L. Cunningham. 1999. Anterograde transport of herpes simplex virus proteins in axons of peripheral human fetal neurons: an immunoelectron microscopy study. J. Virol. 73:8503-8511.
7. Hukkanen, V., H. Mikola, M. Nykänen, and S. Syrjänen. 1999. Herpes simplex virus type 1 infection has two separate modes of spread in three-dimensional keratinocyte culture. J. Gen. Virol. 80:2149-2155.
8. Kaufman, H. E. 1978. Herpetic keratitis. Investig. Ophthalmol. Vis. Sci. 117:941-957.
9. LaVail, J. H., S. Rapisardi, and I. K. Sugino. 1980. Evidence against the smooth endoplasmic reticulum as a continuous channel for the retrograde axonal transport of horseradish peroxidase. Brain Res. 191:3-20.
10. LaVail, J. H., L. B. Meade and C. R. Dawson. 1991. Ultrastructural immunocytochemical localization of herpes simplex virus (type 1) in trigeminal ganglion neurons. Curr. Eye Res. 10(Suppl.):23-29.
11. LaVail, J. H., K. S. Topp, J. A. Garner, and P. A. Giblin. 1997. Factors that contribute to the efficiency of transneuronal spread of herpes simplex virus. J. Neurosci. Res. 49:485-496.
12. LaVail, J. H., J. Zhan, and T. P. Margolis. 1990 HSV (type 1) infection of the trigeminal complex. Brain Res. 514:181-188.
13. Laycock, K. A., S. F. Lee, R. H. Brady, and J. S. Pepose. 1991. Characterization of a murine model of recurrent herpes simplex viral keratitis induced by ultraviolet B radiation. Investig. Ophthalmol. Vis. Sci. 32:2741-2746.
14. Liesegang, T. J. 1989. Epidemiology of ocular herpes simplex. Incidence in Rochester, MN, 1950-1982. Arch. Ophthalmol. 107:1155-1159.
15. Llewellyn-Smith, I. J., P. Pilowsky, and J. B. Minson. 1993. The tungstate-stabilized tetramethylbenzidine reaction for light and electron microscopic immunocytochemistry and for revealing biocytin-filled neurons. J. Neurosci. Methods 46:27-40.
16. Lobmann, A. M., L. J. Müller, E. Pels, P. G. H. Mulder, and L. Remeijer. 1999. Corneal epithelial nerves are the anatomic basis for the dendritic figure caused by herpes simplex virus. Investig. Ophthalmol. Vis. Sci. 40:S549.
17. Lumb, W. V. 1963. Small animal anesthesia. Lea and Febiger, Philadelphia, Pa.
18. Lycke, E., K. Kristensson, B. Svennerholm, A. Vahlne, and R. Ziegler. 1984. Uptake and transport of herpes simplex virus in neurites of rat dorsal root ganglia cells in culture. J. Gen. Virol. 65:55-64.
19. Margolis, T. P., B. Togni, J. H. LaVail, and C. Dawson. 1987. Identifying HSV infected neurons after ocular inoculation. Curr. Eye Res. 6:119-126.
20. McLean, I., and P. Nakane. 1974. Periodate-lysine paraformaldehyde fixative. A new fixative for immunoelectron microscopy. J. Histochem. Cytochem. 22:1077-1083.
21. Miller, J. K., K. A. Laycock, J. A. Umphress, K. K. Hook, P. M. Stuart, and J. S. Pepose. 1996. A comparison of recurrent versus primary HSK in inbred mice. Cornea 15:497-504.
22. Pavan-Langston, D. 1994. Viral disease of the cornea and external eye, p. 117-147. In D. M. Albert and F. A. Jakobic (ed.), Principles and practice of ophthalmology. Lippincott, Philadelphia, Pa.
23. Penfold, M. E. T., P., Armati, and A. L. Cunningham. 1994. Axonal transport of herpes simplex virions to epidermal cells: evidence for a specialized mode of virus transport and assembly. Proc. Natl. Acad. Sci. USA 91:6529-6533.
24. Sawtell, N. M. 1997. Comprehensive quantification of herpes simplex virus latency at the single-cell level. J. Virol. 71:5423-5431.
25. Stanberry, L. R. 1992. Pathogenesis of herpes simplex virus infection and animal models for its study. Curr. Top. Microbiol. Immunol. 179:15-28.
26. Tabery, H. M. 1998. Early epithelial changes in recurrent herpes simplex virus keratitis. Acta Ophthalmol. Scand. 76:349-352.
27. Visalli, R. J., R. J. Courtney, and C. Meyers. 1997. Infection and replication of herpes simplex virus type 1 in an organotypic epithelial culture system. Virology 230:236-243.
28. Whitear, M. 1960. An electron microscope study of the cornea in mice, with special reference to the innervation. J. Anal. 94:387-409.
29. Whitley, R. J. 1996. Herpes simplex virus, p. 2297-2342. In B. N. Fields (ed.), Fields virology. Raven Press, New York, N.Y.
30. Whitley, R. J., D. W. Kimberlin, and B. Roizman. 1998. Herpes simplex viruses. Clin. Infect. Dis. 26:541-553.