Cytoplasmic dyein is required for poleward chromosome movement during mitosis in Drosophila embryos

Nature Cell Biology

Volumn 2, Issue 12, 2000, Pages 922-930

  Sharp, D J ^a   Rogers, G C ^a   Scholey, J M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; DYNACTIN; GREEN FLUORESCENT PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MOLECULAR MOTOR; PHOTOPROTEIN; RECOMBINANT PROTEIN;

ANAPHASE; ARTICLE; CENTROMERE; CHROMOSOME; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA; EMBRYO (ANATOMY); METAPHASE; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSGENIC ANIMAL;

ANAPHASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOMES; CYTOPLASM; DROSOPHILA; DYNEIN ATPASE; GREEN FLUORESCENT PROTEINS; HUMANS; KINETOCHORES; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MITOTIC SPINDLE APPARATUS; MOLECULAR MOTOR PROTEINS; MOVEMENT; RECOMBINANT PROTEINS;

EID: 0033625872     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35046574     Document Type: Article

References (42)

1. Retrograde transport by the microtubule-associated protein MAP 1C
2. Cytoplasmic dynein and dynactin in cell division and intracellular transport
3. Functional coordination of three mitotic motors in drosophila embryos
4. Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation
5. Cytoplasmic dynein is localized to kinetochores during mitosis
6. Localization of cytoplasmic dynein to mitotic spindles and kinetochores
7. Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes
8. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis
9. Zw10 helps recruit dynactin and dynein to the kinetochore
10. Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells
11. Chromosome behavior after laser microirradiation of a single kinetochore in mitotic PtK2 cells
12. Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle
13. Drosophila roadblock and Chlamydomonas LC7: A conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis
14. Rough deal: A gene required for proper mitotic segregation in Drosophila
15. The Drosophila l(1)zw10 gene product, required for accurate mitotic chromosome segregation, is redistributed at anaphase onset
16. Bipolar spindle attachments affect redistributions of Zw10, a Drosophila centromere/kinetochore component required for accurate chromosome segregation
17. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila
18. The cohesion protein ME1-S332 localizes to condensed meiotic and mitotic centromeres until sister chromatids separate
19. The cytoskeleton and morphogenesis of the early Drosophila embryo
20. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
21. Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila
22. The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work
23. Mitosis in living budding yeast: Anaphase A but no metaphase plate
24. Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase
25. Cytoplasmic dynein plays a role in mammalian mitotic spindle formation
26. The rate of poleward chromosome motion is attenuated in Drosophila zw10 and rod mutants
27. Movement of motor and cargo along cilia
28. Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans
29. Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: A push-pull mechanism
30. CENP-E is a putative kinetochore motor that accumulates just before mitosis
31. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment
32. Kin I kinesins are microtubule-destabilizing enzymes
33. Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro
34. Mitotic centromere-associated kinesin is important for anaphase chromosome segregation
35. Kinetochore microtubule dynamics and the metaphase-anaphase transition
36. A quantitative comparison of cellular motile systems
37. Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis
38. Two heteromeric kinesin complexes in chemosensory neurons and sensory cilia of Caenorhabditis elegans
39. Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos
40. Live con focal analysis with fluorescently labeled proteins
41. The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles