A conserved α-herpesvirus protein necessary for axonal localization of viral membrane proteins

Journal of Cell Biology

Volumn 154, Issue 4, 2001, Pages 741-752

  Tomishima, M J ^a   Enquist, L W ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Axonal transport; Herpesvirus; Membrane proteins; Pseudorabies virus; Virus assembly

Indexed keywords

CAPSID PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; PROTEIN GE; PROTEIN US9; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; EMBRYO; HERPES VIRUS; NERVE FIBER; NERVE FIBER TRANSPORT; NONHUMAN; PERIKARYON; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PSEUDORABIES HERPETOVIRUS; RAT; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE; VIRION; VIRUS ADSORPTION; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; AXONS; CELL LINE; CELL POLARITY; CONSERVED SEQUENCE; HERPESVIRUS 1, SUID; LIPOPROTEINS; MODELS, BIOLOGICAL; PHOSPHOPROTEINS; PROTEIN TRANSPORT; SUPERIOR CERVICAL GANGLION; SWINE; VIRAL MATRIX PROTEINS; VIRAL PROTEINS;

ANIMALIA; DNA VIRUSES; HERPESVIRIDAE; RODENTIA; SUID HERPESVIRUS 1;

EID: 0035921429     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200011146     Document Type: Article

References (55)

1. A tyrosine-based motif and a casein kinase II phosphorylation site regulate the intracellular trafficking of the varicella-zoster virus glycoprotein I, a protein localized in the trans-Golgi network
2. Role of essential glycoproteins gII and gp50 in transneuronal transfer of pseudorabies virus from the hypoglossal nerves of mice
3. Deletion of glycoprotein gE reduces the propagation of pseudorabies virus in the nervous system of mice after intranasal inoculation
4. Squid axoplasm supports the retrograde axonal transport of herpes simplex virus
5. Retrograde axonal transport of herpes simplex virus: Evidence for a single mechanism and a role for tegument
6. Molecular bases for the recognition of tyrosine-based sorting signals
7. Serine phosphorylation site of the 46-kDa mannose 6-phosphate receptor is required for transport to the plasma membrane in Madin-Darby canine kidney and mouse fibroblast cells
8. Intracellular trafficking and localization of the pseudorabies virus Us9 type II envelope protein to host and viral membranes
9. Role of pseudorabies virus Us9, a type II membrane protein, in infection of tissue culture cells and the rat nervous system
10. Directional transneuronal infection by pseudorabies virus is dependent on an acidic internalization motif in the Us9 cytoplasmic rail
11. Morphological differentiation of embryonic rat sympathetic neurons in tissue culture. I. Conditions under which neurons form axons but not dendrites
12. Immunocytochemical localization of tubulin and microtubule-associated protein 2 during the development of hippocampal neurons in culture
13. Neurotropic properties of pseudorabies virus: Uptake and transneuronal passage in the rat central nervous system
14. Two alpha-herpesvirus strains are transported differentially in the rodent visual system
15. Pseudorabies virus envelope glycoprotein gl influences both neurotropism and virulence during infection of the rat visual system
16. Pseudorabies virus infection of the rat central nervous system: Ultrastructural characterization of viral replication, transport, and pathogenesis
17. Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid
18. NT-3 stimulates sympathetic neuroblast proliferation by promoting precursor survival
19. Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virus
20. Specific infection of rat neuronal circuits by pseudorabies virus
21. Infection and spread of alphaherpesviruses in the nervous system
22. Changes in the distribution of GAP-43 during the development of neuronal polarity
23. Pseudorabies virus membrane proteins gI and gE facilitate anterograde spread of infection in projection-specific neurons in the rat
24. The polarized sorting of membrane proteins expressed in cultured hippocampal neurons using viral vectors
25. Herpes simplex virus gE/gI sorts nascent virions to epithelial cell junctions, promoting virus spread
26. Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail
27. Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity
28. Linking cargo to vesicle formation: Receptor tail interactions with coat proteins
29. Invasion and spread of single glycoprotein deleted mutants of Aujeszky's disease virus (ADV) in the trigeminal nervous pathway of pigs after intranasal inoculation
30. Role of envelope glycoproteins gI, gp63 and gIII in the invasion and spread of Aujeszky's disease virus in the olfactory nervous pathway of the pig
31. Dissemination of wild-type and gC-, gE-and gI-deleted mutants of Aujeszky's disease virus in the maxillary nerve and trigeminal ganglion of pigs after intranasal inoculation
32. Maturation of the axonal plasma membrane requires upregularion of sphingomyelin synthesis and formation of protein-lipid complexes
33. Sorting out adaptors
34. Massive retinotectal projection in rats
35. Uptake and transport of herpes simplex virus in neurites of rat dorsal root ganglia cells in culture
36. Herpes simplex virus infection of the human sensory neuron. An electron microscopy study
37. Glycoprotein gE-negative pseudorabies virus has a reduced capability to infect second- and third-order neurons of the olfactory and trigeminal routes in the porcine central nervous system
38. Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI
39. Axonal transport of herpes simplex virions to epidermal cells: Evidence for a specialized mode of virus transport and assembly
40. Biochemical and immunological analyses of cytoskeletal domains of neurons
41. Two rat homologs of clathrin-associated adaptor proteins
42. Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetration
43. The replication of herpesviruses
44. Preassembly and transport of nerve terminals: A new concept of axonal transport
45. Clathrin-coated vesicle formation and protein sorting: An integrated process
46. Herpesviruses use bi-directional fast-axonal transport to spread in sensory neurons
47. Mechanisms of viral transport in the cytoplasm
48. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
49. Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain
50. Role of the pseudorabies virus gI cytoplasmic domain in neuroinvasion, virulence, and posttranslational N-linked glycosylation
51. Sorting and transport of alpha herpesviruses in axons
52. Signal-dependent membrane protein trafficking in the enclocytic pathway
53. Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins
54. Casein kinase Il phosphorylates the neural cell adhesion molecule LI
55. Retrograde, transneuronal spread of pseudorabies virus in defined neuronal circuitry of the rat brain is facilitated by gE mutations that reduce virulence