메뉴 건너뛰기




Volumn 4, Issue 3, 2000, Pages 257-262

Evolution of DNA and RNA as catalysts for chemical reactions

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RNA;

EID: 0342313543     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00086-7     Document Type: Review
Times cited : (48)

References (23)
  • 1
    • 0343360846 scopus 로고    scopus 로고
    • In vitro selected oligonucleotides as tools in organic chemistry
    • Jäschke A., Frauendorf C., Hausch F. In vitro selected oligonucleotides as tools in organic chemistry. Synlett. 825-833:1999.
    • (1999) Synlett , vol.825-833
    • Jäschke, A.1    Frauendorf, C.2    Hausch, F.3
  • 4
    • 0033153344 scopus 로고    scopus 로고
    • Boundaries for an RNA world
    • Yarus M. Boundaries for an RNA world. Curr Opin Chem Biol. 3:1999;260-267.
    • (1999) Curr Opin Chem Biol , vol.3 , pp. 260-267
    • Yarus, M.1
  • 5
    • 0032087815 scopus 로고    scopus 로고
    • Oligonucleotide libraries - variatio delectat
    • Famulok M., Jenne A. Oligonucleotide libraries - variatio delectat. Curr Opin Chem Biol. 2:1998;320-327.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 320-327
    • Famulok, M.1    Jenne, A.2
  • 6
    • 0033102314 scopus 로고    scopus 로고
    • A small catalytic RNA motif with Diels Alderase activity
    • This is the first demonstration that a small unmodified RNA can catalyze C-C bond formation. Ribozymes were selected using a linker-coupled anthracene as the diene, and biotinylated maleimide as the dienophile. A 49-nucleotide minimal motif accelerated the reaction about 18,500-fold.
    • Seelig B., Jäschke A. A small catalytic RNA motif with Diels Alderase activity. Chem Biol. 6:1999;167-176. This is the first demonstration that a small unmodified RNA can catalyze C-C bond formation. Ribozymes were selected using a linker-coupled anthracene as the diene, and biotinylated maleimide as the dienophile. A 49-nucleotide minimal motif accelerated the reaction about 18,500-fold.
    • (1999) Chem Biol , vol.6 , pp. 167-176
    • Seelig, B.1    Jäschke, A.2
  • 8
    • 0033601113 scopus 로고    scopus 로고
    • Cholesterol esterase activity by in vitro selection of RNA against a phosphate transition-state analogue
    • This is one of the rare cases in which selection against a transition state analog actually gives a catalyst.
    • Chun S-M., Jeong S., Kim J-M., Chong B-O., Park Y-K., Park H., Yu J. Cholesterol esterase activity by in vitro selection of RNA against a phosphate transition-state analogue. J Am Chem Soc. 121:1999;10844-10845. This is one of the rare cases in which selection against a transition state analog actually gives a catalyst.
    • (1999) J Am Chem Soc , vol.121 , pp. 10844-10845
    • Chun, S.-M.1    Jeong, S.2    Kim, J.-M.3    Chong, B.-O.4    Park, Y.-K.5    Park, H.6    Yu, J.7
  • 9
    • 0032706595 scopus 로고    scopus 로고
    • A tiny RNA that catalyzes both aminoacyl-RNA and peptidyl-RNA synthesis
    • This paper describes a 29-nucleotide RNA catalyzing successively the two related reactions, given phenylalanyl adenylate as substrate. In view of the RNA-world hypothesis, successive aminoacyl- and peptidyl-RNA synthesis by one RNA suggests that uncoded but RNA-catalyzed peptide synthesis would evolve before the synthesis of coded peptides.
    • Illangasekare M., Yarus M. A tiny RNA that catalyzes both aminoacyl-RNA and peptidyl-RNA synthesis. RNA. 5:1999;1482-1489. This paper describes a 29-nucleotide RNA catalyzing successively the two related reactions, given phenylalanyl adenylate as substrate. In view of the RNA-world hypothesis, successive aminoacyl- and peptidyl-RNA synthesis by one RNA suggests that uncoded but RNA-catalyzed peptide synthesis would evolve before the synthesis of coded peptides.
    • (1999) RNA , vol.5 , pp. 1482-1489
    • Illangasekare, M.1    Yarus, M.2
  • 10
    • 0033545853 scopus 로고    scopus 로고
    • Specific, rapid synthesis of Phe-RNA by RNA
    • Illangasekare M., Yarus M. Specific, rapid synthesis of Phe-RNA by RNA. Proc Natl Acad Sci USA. 96:1999;5470-5475.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5470-5475
    • Illangasekare, M.1    Yarus, M.2
  • 11
    • 0033229805 scopus 로고    scopus 로고
    • A ribozyme and a catalytic DNA with peroxidase activity: Active sites versus cofactor-binding sites
    • Travascio P., Bennet A.J., Wang D.Y., Sen D. A ribozyme and a catalytic DNA with peroxidase activity: active sites versus cofactor-binding sites. Chem Biol. 6:1999;779-787.
    • (1999) Chem Biol , vol.6 , pp. 779-787
    • Travascio, P.1    Bennet, A.J.2    Wang, D.Y.3    Sen, D.4
  • 12
    • 0028124128 scopus 로고
    • In vitro evolution of new ribozymes with polynucleotide kinase activity
    • Lorsch J.R., Szostak J.W. In vitro evolution of new ribozymes with polynucleotide kinase activity. Nature. 371:1994;31-36.
    • (1994) Nature , vol.371 , pp. 31-36
    • Lorsch, J.R.1    Szostak, J.W.2
  • 13
    • 0033019927 scopus 로고    scopus 로고
    • Phosphorylating DNA with DNA
    • An illustrative example of the use of in vitro evolution and counter selection to fine-tune the molecular properties of nucleic-acid catalysts. Each of the selected deoxyribozymes makes use of one or more of the eight-standard NTPs or dNTPs as a source of activated phosphate. One optimized deoxyribozyme uses ATP more than 40,000-fold more efficiently than the other ribonucleoside triphosphates.
    • Li Y., Breaker R.R. Phosphorylating DNA with DNA. Proc Natl Acad Sci USA. 96:1999;2746-2751. An illustrative example of the use of in vitro evolution and counter selection to fine-tune the molecular properties of nucleic-acid catalysts. Each of the selected deoxyribozymes makes use of one or more of the eight-standard NTPs or dNTPs as a source of activated phosphate. One optimized deoxyribozyme uses ATP more than 40,000-fold more efficiently than the other ribonucleoside triphosphates.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2746-2751
    • Li, Y.1    Breaker, R.R.2
  • 14
    • 0033581938 scopus 로고    scopus 로고
    • A ribozyme that lacks cytidine
    • Starting from an RNA molecule that contained roughly equal proportions of all four nucleotides, in vitro evolution yielded an RNA ligase ribozyme that completely lacks cytidine.
    • Rogers J., Joyce G.F. A ribozyme that lacks cytidine. Nature. 402:1999;323-325. Starting from an RNA molecule that contained roughly equal proportions of all four nucleotides, in vitro evolution yielded an RNA ligase ribozyme that completely lacks cytidine.
    • (1999) Nature , vol.402 , pp. 323-325
    • Rogers, J.1    Joyce, G.F.2
  • 15
    • 0033485897 scopus 로고    scopus 로고
    • A molecular description of the evolution of resistance
    • Ordoukhanian P., Joyce G.F. A molecular description of the evolution of resistance. Chem Biol. 6:1999;881-889.
    • (1999) Chem Biol , vol.6 , pp. 881-889
    • Ordoukhanian, P.1    Joyce, G.F.2
  • 16
    • 0033524391 scopus 로고    scopus 로고
    • Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: The spandrels of RNA evolution
    • Landweber L.F., Pokrovskaya I.D. Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: the spandrels of RNA evolution. Proc Natl Acad Sci USA. 96:1999;173-178.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 173-178
    • Landweber, L.F.1    Pokrovskaya, I.D.2
  • 17
    • 0032955410 scopus 로고    scopus 로고
    • In vitro selection of an allosteric ribozyme that transduces analytes to amplicons
    • An allosteric ribozyme was selected that is activated by oligonucleotide effectors and conforms to a classic two-state model for allostery.
    • Robertson M.P., Ellington A.D. In vitro selection of an allosteric ribozyme that transduces analytes to amplicons. Nat Biotechnol. 17:1999;62-66. An allosteric ribozyme was selected that is activated by oligonucleotide effectors and conforms to a classic two-state model for allostery.
    • (1999) Nat Biotechnol , vol.17 , pp. 62-66
    • Robertson, M.P.1    Ellington, A.D.2
  • 18
    • 0033616774 scopus 로고    scopus 로고
    • Engineering precision RNA molecular switches
    • Ligand-specific molecular switches composed of RNA were created by coupling pre-existing catalytic and receptor domains by structural bridges. Small organic molecules can switch catalytic activity on or off.
    • Soukup G.A., Breaker R.R. Engineering precision RNA molecular switches. Proc Natl Acad Sci USA. 96:1999;3584-3589. Ligand-specific molecular switches composed of RNA were created by coupling pre-existing catalytic and receptor domains by structural bridges. Small organic molecules can switch catalytic activity on or off.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3584-3589
    • Soukup, G.A.1    Breaker, R.R.2
  • 19
    • 0032755647 scopus 로고    scopus 로고
    • Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP
    • In vitro selected ribozymes are specifically activated by cyclic nucleotide effectors by a factor of 5000, which is the largest allosteric activation of a ribozyme by a small organic molecule reported to date.
    • Koizumi M., Soukup G.A., Kerr J.N., Breaker R.R. Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP. Nat Struct Biol. 6:1999;1062-1071. In vitro selected ribozymes are specifically activated by cyclic nucleotide effectors by a factor of 5000, which is the largest allosteric activation of a ribozyme by a small organic molecule reported to date.
    • (1999) Nat Struct Biol , vol.6 , pp. 1062-1071
    • Koizumi, M.1    Soukup, G.A.2    Kerr, J.N.3    Breaker, R.R.4
  • 21
    • 0031151974 scopus 로고    scopus 로고
    • The joys of in vitro selection: Chemically dressing oligonucleotides to satiate protein targets
    • Eaton B.E. The joys of in vitro selection: chemically dressing oligonucleotides to satiate protein targets. Curr Opin Chem Biol. 1:1997;10-16.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 10-16
    • Eaton, B.E.1
  • 22
    • 0032426662 scopus 로고    scopus 로고
    • The antibody catalysis route to the total synthesis of epothilones
    • Sinha S.C., Barbas C.F. III, Lerner R.A. The antibody catalysis route to the total synthesis of epothilones. Proc Natl Acad Sci USA. 95:1998;14603-14608.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14603-14608
    • Sinha, S.C.1    Barbas C.F. III2    Lerner, R.A.3
  • 23
    • 0031854986 scopus 로고    scopus 로고
    • Man-made cell-like compartments for molecular evolution
    • Tawfik D.S., Griffiths A.D. Man-made cell-like compartments for molecular evolution. Nat Biotechnol. 16:1998;652-656.
    • (1998) Nat Biotechnol , vol.16 , pp. 652-656
    • Tawfik, D.S.1    Griffiths, A.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.