The Fanconi anaemia group G gene FANCG is identical with XRCC9

Nature Genetics

Volumn 20, Issue 3, 1998, Pages 281-283

  De Winter, Johan P ^a   Waisfisz, Quinten ^a   Rooimans, Martin A ^a   Van Berkel, Carola G M ^a   Bosnoyan Collins, Lucine ^b,c   Alon, Noa ^b,c   Carreau, Madeleine ^b,c   Bender, Olaf ^d   Demuth, Ilja ^d   Schindler, Detlev ^e   Pronk, Jan C ^a   Arwert, Fré ^a   Hoehn, Holger ^e   Digweed, Martin ^d   Buchwald, Manuel ^b,c   Joenje, Hans ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HUMBOLDT UNIVERSITY   (Germany)

^e UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 9P; FANCONI ANEMIA; GENE DUPLICATION; GENE ISOLATION; GENE LOCATION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 17344363009     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/3093     Document Type: Article

References (25)

1. Auerbach, A.D., Buchwald, M. & Joenje, H. Fanconi anemia, in The Genetic Basis of Human Cancer (eds Vogelstein, B. & Kinzler, K.W.) 317-332 (McGraw-Hill, New York, 1998).
2. Joenje, H. et al. Evidence for at least eight Fanconi anemia genes. Am. J. Hum. Genet. 61, 940-944 (1997).
3. Buchwald, M. Complementation groups: one or more per gene? Nature Genet. 11, 228-230 (1995).
4. Lo ten Foe, J.R. et al. Expression cloning of a cDNA for the major Fanconi anemia gene. FAA. Nature Genet. 14, 320-323 (1996).
5. The Fanconi anemia/Breast cancer consortium. Positional cloning of Fanconi anemia group A gene. Nature Genet. 14, 324-328 (1996).
6. Strathdee, C.A., Gavish, H., Shannon, W.R. & Buchwald, M. Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature 356, 763-767 (1992).
7. Whitney, M. et al. Microcell mediated chromosome transfer maps the Fanconi anemia group D gene to chromosome 3p. Nature Genet. 11, 341-343 (1995).
8. Saar, K. et al. Localisation of a Fanconi anaemia gene to chromosome 9p. Eur. J. Hum. Genet. 6, 501-508 (1998).
9. Liu, N. et al. The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells. Proc. Natl Acad. Sci. USA 94, 9232-9237 (1997).
10. Busch, D.B. et al. A CHO mutant UV40. that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity. Mutat. Res. 363, 209-221 (1996).
11. Ishida, R. & Buchwald, M. Susceptibility of Fanconi's anemia lymphoblasts to DNA cross-linking and alkylating agents. Cancer Res. 42, 4000-4006 (1982).
12. Schindler, D. & Hoehn, H. Fanconi anemia mutation causes cellular susceptibility to ambient oxygen. Am. J. Hum. Genet. 43, 429-435 (1988).
13. Kupfer, G.M. et al. The Fanconi anemia proteins, FAA and FAC, interact to form a nuclear complex. Nature Genet. 17, 487-490 (1997).
14. Hoatlin, M.E. et al. The Fanconi anemia group C gene product is located both in the nucleus and cytoplasm of human cells. Blood 91, 1418-1425 (1998).
15. Carreau, M. & Buchwald, M. Fanconi's anemia: what have we learned from the genes so far? Mol. Med. Today 4, 201-206 (1998).
16. Kinzler, K.W. & Vogelstein, B. Gatekeepers and caretakers. Nature 386, 761-763 (1997).
17. Levran, O. et al. Sequence variation in the Fanconi anemia gene FAA. Proc. Natl Acad. Sci. USA 94, 13051-13056 (1997).
18. Auerbach, A.D. & Verlander, P.C. Disorders of DNA replication and repair. Curr. Opin. Pediatr. 9, 600-616 (1997).
19. Chen, M. et al. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anemia. Nature Genet. 12, 448-451 (1996).
20. Whitney, M.A. et al. Germ cell defects and hematopoietic hypersensitivity to γ Interferon in mice with a targeted disruption of the Fanconi anemia C gene. Blood 88, 49-58 (1996).
21. Strathdee, C.A., Duncan, A.M.V. & Buchwald, M. Evidence for at least four Fanconi anemia genes including FACC on chromosome 9. Nature Genet. 1, 196-198 (1992).
22. Joenje, H. et al. Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype. Blood 86, 2156-2160 (1995).
23. Savov, A., Angelicheva. D., Jorfanova, A., Eigel, A. & Kalaydjieva, L. High percentage acrylamide gels improve resolution in SSCP analysis. Nucleic Acids Res. 20, 6741-6742 (1992).
24. Moshell, A.N., Tarone, R.E., Newfield, S.A., Andrews, A.D. & Robbins, J.H. A simple and rapid method for evaluating the survival of xeroderma pigmentosum lymphoid lines after irradiation with ultraviolet light. In Vitro 17, 299-307 (1981).
25. Seyschab, H. et al. Comparative evaluation of diepoxybutane sensitivity and cell cycle blockage in the diagnosis of Fanconi anemia. Blood 85, 2233-2237 (1995).