-
1
-
-
0032850651
-
Kinetics of serum tumor marker concentrations and usefulness in clinical monitoring
-
Bidart JM, Thuillier F, Augereau C, et al. Kinetics of serum tumor marker concentrations and usefulness in clinical monitoring. Clin Chem 1999;45:1695-707.
-
(1999)
Clin Chem
, vol.45
, pp. 1695-1707
-
-
Bidart, J.M.1
Thuillier, F.2
Augereau, C.3
-
2
-
-
0141680424
-
Cell signaling and cancer
-
Martin GS. Cell signaling and cancer. Cancer Cell 2003;4:167-74.
-
(2003)
Cancer Cell
, vol.4
, pp. 167-174
-
-
Martin, G.S.1
-
3
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001;411:355-65.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
4
-
-
0025760182
-
Polypeptide growth factors in the regulation of human tumor cell proliferation
-
Kumar R, Mendelsohn J. Polypeptide growth factors in the regulation of human tumor cell proliferation. Curr Opin Oncol 1991;3:70-4.
-
(1991)
Curr Opin Oncol
, vol.3
, pp. 70-74
-
-
Kumar, R.1
Mendelsohn, J.2
-
5
-
-
0035313488
-
FGF and VEGF function in angiogenesis: Signalling pathways, biological responses and therapeutic inhibition
-
Cross MJ, Claesson-Welsh L. FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 2001;22:201-7.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 201-207
-
-
Cross, M.J.1
Claesson-Welsh, L.2
-
6
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-25.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
7
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002;298:1912-34.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
8
-
-
0034693799
-
The protein tyrosine kinase family of the human genome
-
Robinson DR, Wu YM, Lin SF. The protein tyrosine kinase family of the human genome. Oncogene 2000; 19:5548-57.
-
(2000)
Oncogene
, vol.19
, pp. 5548-5557
-
-
Robinson, D.R.1
Wu, Y.M.2
Lin, S.F.3
-
9
-
-
0036490442
-
Smart drugs: Tyrosine kinase inhibitors in cancer therapy
-
Shawver LK, Slamon D, Ullrich A. Smart drugs: tyrosine kinase inhibitors in cancer therapy. Cancer Cell 2002;1:117-23.
-
(2002)
Cancer Cell
, vol.1
, pp. 117-123
-
-
Shawver, L.K.1
Slamon, D.2
Ullrich, A.3
-
10
-
-
12144287534
-
United States Food and Drug Administration drug approval summary: Gefitinib (ZD1839; Iressa) tablets
-
Cohen MH, Williams GA, Sridhara R, et al. United States Food and Drug Administration drug approval summary: gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res 2004;10:1212-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1212-1218
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
-
11
-
-
0036463948
-
Perspectives on the development of a molecularly targeted agent
-
Druker BJ. Perspectives on the development of a molecularly targeted agent. Cancer Cell 2002;1:31-6.
-
(2002)
Cancer Cell
, vol.1
, pp. 31-36
-
-
Druker, B.J.1
-
12
-
-
0347356355
-
Signal transduction inhibitors: A work in progress
-
Becker J. Signal transduction inhibitors: a work in progress. Nat Biotechnol 2004;22:15-8.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 15-18
-
-
Becker, J.1
-
13
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293:876-80.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
15
-
-
0035929652
-
Roots of clinical resistance to STI-571 cancer therapy
-
Hochhaus A, Kreil S, Corbin A, et al. Roots of clinical resistance to STI-571 cancer therapy. Science 2001; 293:2163.
-
(2001)
Science
, vol.293
, pp. 2163
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.3
-
16
-
-
0036678472
-
Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop
-
Roumiantsev S, Shah NP, Gorre ME, et al. Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop. Proc Natl Acad Sci U S A 2000; 99:10700-5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10700-10705
-
-
Roumiantsev, S.1
Shah, N.P.2
Gorre, M.E.3
-
17
-
-
0141723426
-
Gleevec resistance: Lessons for target-directed drug development
-
Daley GQ. Gleevec resistance: lessons for target-directed drug development. Cell Cycle 2003;2:190-1.
-
(2003)
Cell Cycle
, vol.2
, pp. 190-191
-
-
Daley, G.Q.1
-
18
-
-
0037315281
-
Molecular mechanisms of resistance to imatinib in Philadelphia- chromosome-positive leukaemias
-
Gambacorti-Passerini CB, Gunby RH, Piazza R, Galietta A, Rostagno R, Scapozza L. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol 2003; 4:75-85.
-
(2003)
Lancet Oncol
, vol.4
, pp. 75-85
-
-
Gambacorti-Passerini, C.B.1
Gunby, R.H.2
Piazza, R.3
Galietta, A.4
Rostagno, R.5
Scapozza, L.6
-
19
-
-
12144290914
-
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
-
Mitsiades CS, Mitsiades NS, McMullan CJ, et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 2004;5:221-30.
-
(2004)
Cancer Cell
, vol.5
, pp. 221-230
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
20
-
-
12144285705
-
In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase
-
Garcia-Echeverria C, Pearson MA, Marti A, et al. In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase. Cancer Cell 2004;5:231-9.
-
(2004)
Cancer Cell
, vol.5
, pp. 231-239
-
-
Garcia-Echeverria, C.1
Pearson, M.A.2
Marti, A.3
-
21
-
-
0037115644
-
Activity of the Bcr-Abl kinase inhibitor PO180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571)
-
La Rosee P, Corbin AS, Stoffregen EP, Deininger MW, Druker BJ. Activity of the Bcr-Abl kinase inhibitor PO180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571). Cancer Res 2002;62:7149-53.
-
(2002)
Cancer Res
, vol.62
, pp. 7149-7153
-
-
La Rosee, P.1
Corbin, A.S.2
Stoffregen, E.P.3
Deininger, M.W.4
Druker, B.J.5
-
22
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah NP,Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 2004;305:399-401.
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
24
-
-
0036097364
-
The origins of protein phosphorylation
-
Cohen P. The origins of protein phosphorylation. Nat Cell Biol 2002;4:E127-30.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Cohen, P.1
-
25
-
-
18244404089
-
Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells
-
Ohmine K, Ota J, Ueda M, et al. Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells. Oncogene 2001;20:8249-57.
-
(2001)
Oncogene
, vol.20
, pp. 8249-8257
-
-
Ohmine, K.1
Ota, J.2
Ueda, M.3
-
26
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-74.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
27
-
-
0038244058
-
Gene expression predictors of breast cancer outcomes
-
Huang E, Cheng SH, Dressman H, et al. Gene expression predictors of breast cancer outcomes. Lancet 2003;361:1590-6.
-
(2003)
Lancet
, vol.361
, pp. 1590-1596
-
-
Huang, E.1
Cheng, S.H.2
Dressman, H.3
-
28
-
-
0038137601
-
Gene expression profiles of human breast cancer progression
-
Ma XJ, Salunga R, Tuggle JT, et al. Gene expression profiles of human breast cancer progression. Proc Natl Acad Sci U S A 2003;100:5974-9.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5974-5979
-
-
Ma, X.J.1
Salunga, R.2
Tuggle, J.T.3
-
29
-
-
0042125511
-
Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
-
Chang JC, Wooten EC, Tsimelzon A, et al. Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet 2003;362:362-9.
-
(2003)
Lancet
, vol.362
, pp. 362-369
-
-
Chang, J.C.1
Wooten, E.C.2
Tsimelzon, A.3
-
30
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002;415:530-6.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
Veer, L.J.1
Dai, H.2
Van De Vijver, M.J.3
-
31
-
-
0036144678
-
Global gene expression analysis of gastric cancer by oligonucleotide microarrays
-
Hippo Y, Taniguchi H, Tsutsumi S, et al. Global gene expression analysis of gastric cancer by oligonucleotide microarrays. Cancer Res 2002;62:233-40.
-
(2002)
Cancer Res
, vol.62
, pp. 233-240
-
-
Hippo, Y.1
Taniguchi, H.2
Tsutsumi, S.3
-
32
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406: 747-52.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
33
-
-
0347201147
-
Multi-class cancer diagnosis using tumor gene expression signatures
-
Ramaswamy S, Tamayo P, Rifkin R, et al. Multi-class cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci U S A 2001;98: 15149-54.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 15149-15154
-
-
Ramaswamy, S.1
Tamayo, P.2
Rifkin, R.3
-
34
-
-
0035949684
-
Predicting the clinical status of human breast cancer by using gene expression profiles
-
West M, Blanchette C, Dressman H, et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci U S A 2001;98:11462-7.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11462-11467
-
-
West, M.1
Blanchette, C.2
Dressman, H.3
-
35
-
-
0037165140
-
Prediction of central nervous system embryonal tumour outcome based on gene expression
-
Pomeroy SL, Tamayo P, Gaasenbeek M, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 2002;415:436-42.
-
(2002)
Nature
, vol.415
, pp. 436-442
-
-
Pomeroy, S.L.1
Tamayo, P.2
Gaasenbeek, M.3
-
36
-
-
33748714310
-
Transcriptional profiling develops molecular signatures for ovarian tumors
-
Smith DI. Transcriptional profiling develops molecular signatures for ovarian tumors. Cytometry 2002;47: 60-2.
-
(2002)
Cytometry
, vol.47
, pp. 60-62
-
-
Smith, D.I.1
-
37
-
-
0035489608
-
Proteomics of breast cancer for marker discovery and signal pathway profiling
-
Hondermarck H, Vercoutter-Edouart AS, Revillion F, et al. Proteomics of breast cancer for marker discovery and signal pathway profiling. Proteomics 2001;1: 1216-32.
-
(2001)
Proteomics
, vol.1
, pp. 1216-1232
-
-
Hondermarck, H.1
Vercoutter-Edouart, A.S.2
Revillion, F.3
-
38
-
-
0037112454
-
Proteomics of human breast ductal carcinoma in situ
-
Wulfkuhle JD, Sgroi DC, Krutzsch H, et al. Proteomics of human breast ductal carcinoma in situ. Cancer Res 2002;62:6740-9.
-
(2002)
Cancer Res
, vol.62
, pp. 6740-6749
-
-
Wulfkuhle, J.D.1
Sgroi, D.C.2
Krutzsch, H.3
-
39
-
-
0035487804
-
New approaches to proteomic analysis of breast cancer
-
Wulfkuhle JD, McLean KC, Paweletz CP, et al. New approaches to proteomic analysis of breast cancer. Proteomics 2001;1:1205-15.
-
(2001)
Proteomics
, vol.1
, pp. 1205-1215
-
-
Wulfkuhle, J.D.1
McLean, K.C.2
Paweletz, C.P.3
-
40
-
-
0034103928
-
Molecular interactions in the Vogelstein model of colorectal carcinoma
-
Arends JW. Molecular interactions in the Vogelstein model of colorectal carcinoma. J Pathol 2000;190: 412-6.
-
(2000)
J Pathol
, vol.190
, pp. 412-416
-
-
Arends, J.W.1
-
41
-
-
0027442278
-
Genetics, molecular biology and colorectal cancer
-
Finlay GJ. Genetics, molecular biology and colorectal cancer. Mutat Res 1993;290:3-12.
-
(1993)
Mutat Res
, vol.290
, pp. 3-12
-
-
Finlay, G.J.1
-
42
-
-
3042552362
-
HER-2 gene amplification can be acquired as breast cancer progresses
-
Meng S, Tripathy D, Shete S, et al. HER-2 gene amplification can be acquired as breast cancer progresses. Proc Natl Acad Sci U S A 2004;101:9393-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9393-9398
-
-
Meng, S.1
Tripathy, D.2
Shete, S.3
-
43
-
-
3042626249
-
Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: Implications for adjuvant use of kinase-inhibitory drugs
-
Lim YP, Wong CY, Ooi LL, Druker BJ, Epstein RJ. Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs. Clin Cancer Res 2004;10:3980-7.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3980-3987
-
-
Lim, Y.P.1
Wong, C.Y.2
Ooi, L.L.3
Druker, B.J.4
Epstein, R.J.5
-
44
-
-
0028061615
-
Heat shock proteins and drug resistances
-
Fuqua SA, Oesterreich S, Hilsenbeck SG, Von Hoff DD, Eckardt J, Osborne CK. Heat shock proteins and drug resistances. Breast Cancer Res Treat 1994;32: 67-71.
-
(1994)
Breast Cancer Res Treat
, vol.32
, pp. 67-71
-
-
Fuqua, S.A.1
Oesterreich, S.2
Hilsenbeck, S.G.3
Von Hoff, D.D.4
Eckardt, J.5
Osborne, C.K.6
-
45
-
-
0030474514
-
Role of intermediate filaments in migration, invasion and metastasis
-
Hendrix MJ, Seftor EA, Chu YW, Trevor KT, Seftor RE. Role of intermediate filaments in migration, invasion and metastasis. Cancer Metastasis Rev 1996;15:507-25.
-
(1996)
Cancer Metastasis Rev
, vol.15
, pp. 507-525
-
-
Hendrix, M.J.1
Seftor, E.A.2
Chu, Y.W.3
Trevor, K.T.4
Seftor, R.E.5
-
46
-
-
0031459864
-
p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
-
Carpino N, Wisniewski D, Strife A, et al. p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 1997;88:197-204.
-
(1997)
Cell
, vol.88
, pp. 197-204
-
-
Carpino, N.1
Wisniewski, D.2
Strife, A.3
-
47
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
48
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
49
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004;6:117-27.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
50
-
-
7144227948
-
Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression
-
Yamauchi T, Ueki K, Tobe K, et al. Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression. Endocr J 1998;45 Suppl:S27-31.
-
(1998)
Endocr J
, vol.45
, Issue.SUPPL.
-
-
Yamauchi, T.1
Ueki, K.2
Tobe, K.3
-
51
-
-
0030656447
-
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
-
Yamauchi T, Ueki K, Tobe K, et al. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature 1997;390:91-6.
-
(1997)
Nature
, vol.390
, pp. 91-96
-
-
Yamauchi, T.1
Ueki, K.2
Tobe, K.3
-
52
-
-
1942424869
-
Salivary phospholipid secretion in response to β-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transaclivation
-
Slomiany BL, Slomiany A. Salivary phospholipid secretion in response to β-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transaclivation. Biochem Biophys Res Commun 2004;318:247-52.
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 247-252
-
-
Slomiany, B.L.1
Slomiany, A.2
-
53
-
-
1242316984
-
Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains
-
Hur EM, Park YS, Lee BD, et al. Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains. J Biol Chem 2004;279:5852-60.
-
(2004)
J Biol Chem
, vol.279
, pp. 5852-5860
-
-
Hur, E.M.1
Park, Y.S.2
Lee, B.D.3
-
54
-
-
0035827528
-
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
-
Andreev J, Galisteo ML, Kranenburg O, et al. Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. J Biol Chem 2001;276:20130-5.
-
(2001)
J Biol Chem
, vol.276
, pp. 20130-20135
-
-
Andreev, J.1
Galisteo, M.L.2
Kranenburg, O.3
-
55
-
-
0030614911
-
Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
-
Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK, Lefkowitz RJ. Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem 1997;272:4637-44.
-
(1997)
J Biol Chem
, vol.272
, pp. 4637-4644
-
-
Luttrell, L.M.1
Della Rocca, G.J.2
Van Biesen, T.3
Luttrell, D.K.4
Lefkowitz, R.J.5
-
56
-
-
0033583220
-
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ. c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 1999;274:8335-43.
-
(1999)
J Biol Chem
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
Cox, M.E.4
Leu, T.H.5
Parsons, S.J.6
-
57
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, et al. Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 2004;36:453-61.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
-
58
-
-
0035067251
-
Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome
-
Oda Y, Nagasu T, Chait BT. Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome. Nat Biotechnol 2001;19:379-82.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 379-382
-
-
Oda, Y.1
Nagasu, T.2
Chait, B.T.3
-
59
-
-
0035072715
-
A systematic approach to the analysis of protein phosphorylation
-
Zhou H, Watts JD, Aebersold R. A systematic approach to the analysis of protein phosphorylation. Nat Biotechnol 2001;19:375-8.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 375-378
-
-
Zhou, H.1
Watts, J.D.2
Aebersold, R.3
-
60
-
-
0035356565
-
Phosphoprotein isotope-coded affinity tag approach for isolating and quantitating phosphopeptides in proteome-wide analyses
-
Goshe MB, Conrads TP, Panisko EA, Angell NH, Veenstra TD, Smith RD. Phosphoprotein isotope-coded affinity tag approach for isolating and quantitating phosphopeptides in proteome-wide analyses. Anal Chem 2001;73:2578-86.
-
(2001)
Anal Chem
, vol.73
, pp. 2578-2586
-
-
Goshe, M.B.1
Conrads, T.P.2
Panisko, E.A.3
Angell, N.H.4
Veenstra, T.D.5
Smith, R.D.6
-
61
-
-
0036198435
-
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae
-
Ficarro SB, McCleland ML, Stukenberg PT, et al. Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol 2002;20:301-5.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 301-305
-
-
Ficarro, S.B.1
McCleland, M.L.2
Stukenberg, P.T.3
-
62
-
-
0037458030
-
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry
-
Salomon AR, Ficarro SB, Brill LM, et al. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proc Natl Acad Sci U S A 2003;100:443-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 443-448
-
-
Salomon, A.R.1
Ficarro, S.B.2
Brill, L.M.3
-
63
-
-
0028237972
-
Purification and identification of tyrosine-phosphorylated proteins from B lymphocytes stimulated through the antigen receptor
-
Gold MR, Yungwirth T, Sutherland CL, et al. Purification and identification of tyrosine-phosphorylated proteins from B lymphocytes stimulated through the antigen receptor. Electrophoresis 1994;15: 441-53.
-
(1994)
Electrophoresis
, vol.15
, pp. 441-453
-
-
Gold, M.R.1
Yungwirth, T.2
Sutherland, C.L.3
-
64
-
-
0034602654
-
Analysis of receptor signaling pathways by mass spectrometry: Identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors
-
Pandey A, Podtelejnikov AV, Blagoev B, Bustelo XR, Mann M, Lodish HF. Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors. Proc Natl Acad Sci U S A 2000;97:179-84.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 179-184
-
-
Pandey, A.1
Podtelejnikov, A.V.2
Blagoev, B.3
Bustelo, X.R.4
Mann, M.5
Lodish, H.F.6
-
65
-
-
0039846981
-
Functional proteomics analysis of signal transduction pathways of the platelet-derived growth factor β receptor (actin, cortactin)
-
Soskic V, Gorlach M, Poznanovic S, Boehmer FD, Godovac-Zimmermann J. Functional proteomics analysis of signal transduction pathways of the platelet-derived growth factor β receptor (actin, cortactin). Biochemistry 1999;38:1757-64.
-
(1999)
Biochemistry
, vol.38
, pp. 1757-1764
-
-
Soskic, V.1
Gorlach, M.2
Poznanovic, S.3
Boehmer, F.D.4
Godovac-Zimmermann, J.5
-
66
-
-
0034120638
-
Matrix assisted laser desorption/ionization-time of flight-mass spectrometry analysis of proteins detected by anti-phosphotyrosine antibody on two-dimensional-gels of fibroblast cell lysates after tumor necrosis factor-α stimulation (HSC71, Grp75, grp78, tubulin, integrin b4)
-
Yanagida M, Miura Y, Yagasaki K, Taoka M, Isobe T, Takahashi N. Matrix assisted laser desorption/ionization-time of flight-mass spectrometry analysis of proteins detected by anti-phosphotyrosine antibody on two-dimensional-gels of fibroblast cell lysates after tumor necrosis factor-α stimulation (HSC71, Grp75, grp78, tubulin, integrin b4). Electrophoresis 2000;21: 1890-8.
-
(2000)
Electrophoresis
, vol.21
, pp. 1890-1898
-
-
Yanagida, M.1
Miura, Y.2
Yagasaki, K.3
Taoka, M.4
Isobe, T.5
Takahashi, N.6
-
67
-
-
4444371652
-
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics
-
Blagoev B, Ong SE, Kratchmarova I, Mann M. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat Biotechnol 2004;22:1139-45.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1139-1145
-
-
Blagoev, B.1
Ong, S.E.2
Kratchmarova, I.3
Mann, M.4
-
68
-
-
0024425432
-
Oncogenes, growth factors, and signal transduction
-
Druker BJ, Mamon HJ, Roberts TM. Oncogenes, growth factors, and signal transduction. N Engl J Med 1989;321:1383-91.
-
(1989)
N Engl J Med
, vol.321
, pp. 1383-1391
-
-
Druker, B.J.1
Mamon, H.J.2
Roberts, T.M.3
-
69
-
-
3042608563
-
Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells
-
Lim YP, Diong LS, Qi R, Druker BJ, Epstein RJ. Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells. Mol Cancer Ther 2003;2:1369-77.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1369-1377
-
-
Lim, Y.P.1
Diong, L.S.2
Qi, R.3
Druker, B.J.4
Epstein, R.J.5
-
70
-
-
0034866917
-
A decade of site- and phosphorylation state-specific antibodies: Recent advances in studies of spatiotemporal protein phosphorylation
-
Nagata K, Izawa I, Inagaki M. A decade of site- and phosphorylation state-specific antibodies: recent advances in studies of spatiotemporal protein phosphorylation. Genes Cells 2001;6: 653-64.
-
(2001)
Genes Cells
, vol.6
, pp. 653-664
-
-
Nagata, K.1
Izawa, I.2
Inagaki, M.3
-
71
-
-
9444287030
-
Common and distinct elements in cellular signaling via EGF and FGF receptors
-
Schlessinger J. Common and distinct elements in cellular signaling via EGF and FGF receptors. Science 2004;306:1506-7.
-
(2004)
Science
, vol.306
, pp. 1506-1507
-
-
Schlessinger, J.1
-
72
-
-
0026406102
-
Interactions of growth factor receptors with cytoplasmic signaling molecules
-
Williams LT, Escobedo JA, Fantl WJ, Turck CW, Klippel A. Interactions of growth factor receptors with cytoplasmic signaling molecules. Cold Spring Harb Symp Quant Biol 1991;56:243-50.
-
(1991)
Cold Spring Harb Symp Quant Biol
, vol.56
, pp. 243-250
-
-
Williams, L.T.1
Escobedo, J.A.2
Fantl, W.J.3
Turck, C.W.4
Klippel, A.5
-
73
-
-
0033001789
-
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
-
Xu W, Doshi A, Lei M, Eck MJ, Harrison SC. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol Cell 1999;3:629-38.
-
(1999)
Mol Cell
, vol.3
, pp. 629-638
-
-
Xu, W.1
Doshi, A.2
Lei, M.3
Eck, M.J.4
Harrison, S.C.5
-
74
-
-
0026491009
-
Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor
-
Epstein RJ, Druker BJ, Roberts TM, Stiles CD. Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor. Proc Natl Acad Sci U S A 1992;89:10435-9.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10435-10439
-
-
Epstein, R.J.1
Druker, B.J.2
Roberts, T.M.3
Stiles, C.D.4
-
75
-
-
0033535718
-
Detection of ErbB2 oversignalling in a majority of breast cancers with phosphorylation-state-specific antibodies
-
Ouyang X, Gulliford T, Doherty A, Huang GC, Epstein RJ. Detection of ErbB2 oversignalling in a majority of breast cancers with phosphorylation-state- specific antibodies. Lancet 1999;353:1591-2.
-
(1999)
Lancet
, vol.353
, pp. 1591-1592
-
-
Ouyang, X.1
Gulliford, T.2
Doherty, A.3
Huang, G.C.4
Epstein, R.J.5
-
76
-
-
0035079810
-
Multisite phosphotyping of the ErbB-2 oncoprotein in human breast cancer
-
Ouyang X, Gulliford T, Huang GC, Harper-Wynne C, Shousha S, Epstein RJ. Multisite phosphotyping of the ErbB-2 oncoprotein in human breast cancer. Mol Diagn 2001;6:17-25.
-
(2001)
Mol Diagn
, vol.6
, pp. 17-25
-
-
Ouyang, X.1
Gulliford, T.2
Huang, G.C.3
Harper-Wynne, C.4
Shousha, S.5
Epstein, R.J.6
-
77
-
-
0034745034
-
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer
-
Ouyang X, Gulliford T, Zhang H, Smith G, Huang G, Epstein RJ. Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer. Mol Cell Biochem 2001;218:47-54.
-
(2001)
Mol Cell Biochem
, vol.218
, pp. 47-54
-
-
Ouyang, X.1
Gulliford, T.2
Zhang, H.3
Smith, G.4
Huang, G.5
Epstein, R.J.6
-
78
-
-
0032526481
-
Adjacent carboxyterminal tyrosine phosphorylation events identify functionally distinct ErbB2 receptor subsets: Implications for molecular diagnostics
-
Ouyang X, Huang GC, Chantry A, Epstein RJ. Adjacent carboxyterminal tyrosine phosphorylation events identify functionally distinct ErbB2 receptor subsets: implications for molecular diagnostics. Exp Cell Res 1998;241:467-75.
-
(1998)
Exp Cell Res
, vol.241
, pp. 467-475
-
-
Ouyang, X.1
Huang, G.C.2
Chantry, A.3
Epstein, R.J.4
-
79
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
Irish JM, Hovland R, Krutzik PO, et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 2004;118:217-28.
-
(2004)
Cell
, vol.118
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
-
80
-
-
2342590659
-
β-catenin and p53 analyses of a breast carcinoma tissue microarray
-
Chung GG, Zerkowski MP, Ocal IT, et al. β-Catenin and p53 analyses of a breast carcinoma tissue microarray. Cancer 2004;100:2084-92.
-
(2004)
Cancer
, vol.100
, pp. 2084-2092
-
-
Chung, G.G.1
Zerkowski, M.P.2
Ocal, I.T.3
-
82
-
-
1542270084
-
Applications of microarrays to histopathology
-
van de Rijn M, Gilks CB. Applications of microarrays to histopathology. Histopathology 2004;44: 97-108.
-
(2004)
Histopathology
, vol.44
, pp. 97-108
-
-
Van De Rijn, M.1
Gilks, C.B.2
-
83
-
-
0031810796
-
Expression of phospholipase C-γ 1 and its transcriptional regulators in breast cancer tissues
-
Noh DY, Kang HS, Kim YC, et al. Expression of phospholipase C-γ 1 and its transcriptional regulators in breast cancer tissues. Anticancer Res 1998;18:2643-8.
-
(1998)
Anticancer Res
, vol.18
, pp. 2643-2648
-
-
Noh, D.Y.1
Kang, H.S.2
Kim, Y.C.3
-
84
-
-
0028858730
-
Overexpression of phospholipase C-γ 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoter
-
Lee SJ, Lee SD, Park JG, Kim CM, Ryu SH, Suh PG. Overexpression of phospholipase C-γ 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoter. J Biol Chem 1995;270: 16378-84.
-
(1995)
J Biol Chem
, vol.270
, pp. 16378-16384
-
-
Lee, S.J.1
Lee, S.D.2
Park, J.G.3
Kim, C.M.4
Ryu, S.H.5
Suh, P.G.6
-
85
-
-
0028083941
-
Overexpression of phospholipase C-γ 1 in familial adenomatous polyposis
-
Park JG, Lee YH, Kim SS, et al. Overexpression of phospholipase C-γ 1 in familial adenomatous polyposis. Cancer Res 1994;54:2240-4.
-
(1994)
Cancer Res
, vol.54
, pp. 2240-2244
-
-
Park, J.G.1
Lee, Y.H.2
Kim, S.S.3
-
86
-
-
0027934898
-
Overexpression of the Grb2 gene in human breast cancer cell lines
-
Daly RJ, Binder MD, Sutherland RL. Overexpression of the Grb2 gene in human breast cancer cell lines. Oncogene 1994;9:2723-7.
-
(1994)
Oncogene
, vol.9
, pp. 2723-2727
-
-
Daly, R.J.1
Binder, M.D.2
Sutherland, R.L.3
-
87
-
-
0030867556
-
Grb2 overexpression in nuclei and cytoplasm of human breast cells: A histochemical and biochemical study of normal and neoplastic mammary tissue specimens
-
Verbeek BS, Adriaansen-Slot SS, Rijksen G, Vroom TM. Grb2 overexpression in nuclei and cytoplasm of human breast cells: a histochemical and biochemical study of normal and neoplastic mammary tissue specimens. J Pathol 1997;183:195-203.
-
(1997)
J Pathol
, vol.183
, pp. 195-203
-
-
Verbeek, B.S.1
Adriaansen-Slot, S.S.2
Rijksen, G.3
Vroom, T.M.4
-
88
-
-
3242877904
-
Analysis of Ki-ras gene mutations within the same tumor using a single tumor crypt in colorectal carcinomas
-
Ishii M, Sugai T, Habano W, Nakamura S. Analysis of Ki-ras gene mutations within the same tumor using a single tumor crypt in colorectal carcinomas. J Gastroenterol 2004;39:544-9.
-
(2004)
J Gastroenterol
, vol.39
, pp. 544-549
-
-
Ishii, M.1
Sugai, T.2
Habano, W.3
Nakamura, S.4
-
89
-
-
0033835421
-
The importance of being K-Ras
-
Ellis CA, Clark G. The importance of being K-Ras. Cell Signal 2000;12:425-34.
-
(2000)
Cell Signal
, vol.12
, pp. 425-434
-
-
Ellis, C.A.1
Clark, G.2
-
90
-
-
0036675635
-
The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer
-
Daly RJ, Gu H, Parmar J, et al. The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer. Oncogene 2002;21:5175-81.
-
(2002)
Oncogene
, vol.21
, pp. 5175-5181
-
-
Daly, R.J.1
Gu, H.2
Parmar, J.3
-
91
-
-
0242499482
-
Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3′-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas
-
Knobbe CB, Reifenberger G. Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3′-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas. Brain Pathol 2003;13:507-18.
-
(2003)
Brain Pathol
, vol.13
, pp. 507-518
-
-
Knobbe, C.B.1
Reifenberger, G.2
-
92
-
-
0036314050
-
Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma
-
Mishima K, Inoue K, Hayashi Y. Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma. Oral Oncol 2002;38: 468-74.
-
(2002)
Oral Oncol
, vol.38
, pp. 468-474
-
-
Mishima, K.1
Inoue, K.2
Hayashi, Y.3
-
93
-
-
0033581954
-
Increased protein kinase C δ in mammary tumor cells: Relationship to transformation and metastatic progression
-
Kiley SC, Clark KJ, Duddy SK, Welch DR, Jaken S. Increased protein kinase C δ in mammary tumor cells: relationship to transformation and metastatic progression. Oncogene 1999;18:6748-57.
-
(1999)
Oncogene
, vol.18
, pp. 6748-6757
-
-
Kiley, S.C.1
Clark, K.J.2
Duddy, S.K.3
Welch, D.R.4
Jaken, S.5
|