-
1
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3
-
Dammann, R., Li, C., Yoon, J. H., Chin, P. L., Bates, S., and Pfeifer, G. P. Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3. Nat. Genet., 25: 315-319, 2000.
-
(2000)
Nat. Genet.
, vol.25
, pp. 315-319
-
-
Dammann, R.1
Li, C.2
Yoon, J.H.3
Chin, P.L.4
Bates, S.5
Pfeifer, G.P.6
-
2
-
-
0037096818
-
The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
-
Kuzmin, I. K., Gillespie, J. W., Protopopov, A., Geil, L., Dreijerink, K., Yang, Y., Vocke, C. D., Duh, F-M., Zabarovsky, E., Minna, J. D., Rhim, J. S., Emmert-Buck, M. R., Linehan, W. M., and Lerman, M. I. The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells. Cancer Res., 62: 3498-3502, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 3498-3502
-
-
Kuzmin, I.K.1
Gillespie, J.W.2
Protopopov, A.3
Geil, L.4
Dreijerink, K.5
Yang, Y.6
Vocke, C.D.7
Duh, F.-M.8
Zabarovsky, E.9
Minna, J.D.10
Rhim, J.S.11
Emmert-Buck, M.R.12
Linehan, W.M.13
Lerman, M.I.14
-
3
-
-
0035872408
-
High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma
-
Lo, K-W., Kwong, J., Hui, A. B-Y., Chan, S. Y-Y., To, K-F., Chan, S-C., Chow, L. S-N., Teo, P. M. L., Johnson, P. J., and Huang, D. P. High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma. Cancer Res., 61: 3877-3881, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 3877-3881
-
-
Lo, K.-W.1
Kwong, J.2
Hui, A.B.-Y.3
Chan, S.Y.-Y.4
To, K.-F.5
Chan, S.-C.6
Chow, L.S.-N.7
Teo, P.M.L.8
Johnson, P.J.9
Huang, D.P.10
-
4
-
-
0035932393
-
Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumors
-
Agathanggelou, A., Honorio, S., Macartney, D. P., Martinez, A., Dallol, A., Rader, J., Fullwood, P., Chauhan, A., Walker, R., Shaw, J. A., Hosoe, S., Lerman, M. I., Minna, J. D., Maher, E. R., and Latif, F. Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumors. Oncogene, 20: 1509-1518, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 1509-1518
-
-
Agathanggelou, A.1
Honorio, S.2
Macartney, D.P.3
Martinez, A.4
Dallol, A.5
Rader, J.6
Fullwood, P.7
Chauhan, A.8
Walker, R.9
Shaw, J.A.10
Hosoe, S.11
Lerman, M.I.12
Minna, J.D.13
Maher, E.R.14
Latif, F.15
-
5
-
-
0037108984
-
Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development
-
Lusher, M. E., Lindsey, J. C., Latif, F. L., Pearson, A. D. J., Ellison, D. W., and Clifford, S. C. Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development. Cancer Res., 62: 5906-5911, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 5906-5911
-
-
Lusher, M.E.1
Lindsey, J.C.2
Latif, F.L.3
Pearson, A.D.J.4
Ellison, D.W.5
Clifford, S.C.6
-
6
-
-
0035795676
-
The RASSF1A locus in the 3p21.3 homozygous deletion region: Epigenetic inactivation in lung and breast cancer and suppression of the malignant phenotype
-
Burbce, D. G., Forgacs, E., Zochbauer-Muller, S., Shivakumar, L., Fong, K., Gao, B., Randle, D., Virmani, A., Bader, Y., Sekido, Y., Latif, F., Milchgrub, S., Toyooka, S., Gadzar, A. F., Lerman, M. I., Zabarovsky, E., White, M., and Minna, J. D. The RASSF1A locus in the 3p21.3 homozygous deletion region: epigenetic inactivation in lung and breast cancer and suppression of the malignant phenotype. J. Natl. Cancer Inst. (Bethesda), 93: 691-699, 2001.
-
(2001)
J. Natl. Cancer Inst. (Bethesda)
, vol.93
, pp. 691-699
-
-
Burbce, D.G.1
Forgacs, E.2
Zochbauer-Muller, S.3
Shivakumar, L.4
Fong, K.5
Gao, B.6
Randle, D.7
Virmani, A.8
Bader, Y.9
Sekido, Y.10
Latif, F.11
Milchgrub, S.12
Toyooka, S.13
Gadzar, A.F.14
Lerman, M.I.15
Zabarovsky, E.16
White, M.17
Minna, J.D.18
-
7
-
-
0035300429
-
Hypermethylation of the CpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers
-
Dammann, R., Yang, G., and Pfeifer, G. P. Hypermethylation of the CpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res., 61: 3105-3109, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 3105-3109
-
-
Dammann, R.1
Yang, G.2
Pfeifer, G.P.3
-
8
-
-
0037133034
-
Identification of a novel Ras-regulated proapoptotic pathway
-
Khokhlatchev, A., Rabizadeh, S., Xavier, R., Nedwidek, M., Chen, T., Zhang, X-F., Seed, B., and Avruch, J. Identification of a novel Ras-regulated proapoptotic pathway. Curr. Biol., 12: 253-265, 2002.
-
(2002)
Curr. Biol.
, vol.12
, pp. 253-265
-
-
Khokhlatchev, A.1
Rabizadeh, S.2
Xavier, R.3
Nedwidek, M.4
Chen, T.5
Zhang, X.-F.6
Seed, B.7
Avruch, J.8
-
9
-
-
0032489384
-
Identification of Norel as a potential ras effector
-
Vavvas, D., Li, X., Avruch, J., and Zhang, X-F. Identification of Norel as a potential ras effector. J. Biol. Chem., 273: 5439-5442, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5439-5442
-
-
Vavvas, D.1
Li, X.2
Avruch, J.3
Zhang, X.-F.4
-
10
-
-
0034327412
-
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes
-
Lerman, M. I., and Minna, J. D. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes. Cancer Res., 60: 6116-6133, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 6116-6133
-
-
Lerman, M.I.1
Minna, J.D.2
-
11
-
-
0034680870
-
Ras uses the novel tumor suppressor RASSF1A as an effector to mediate apoptosis
-
Vos, M. D., Ellis, C. A., Bell, A., Birrer, M. J., and Clark, G. J. Ras uses the novel tumor suppressor RASSF1A as an effector to mediate apoptosis. J. Biol. Chem., 275: 35669-35672, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35669-35672
-
-
Vos, M.D.1
Ellis, C.A.2
Bell, A.3
Birrer, M.J.4
Clark, G.J.5
-
12
-
-
85047696339
-
The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore 1
-
Ortiz-Vega, S., Khokhlatchev, A., Nedwidek, M., Zhang, X., Dammann, R., Pfeifer, G. P., and Avruch, J. The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore 1. Oncogene, 21: 1381-1390, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 1381-1390
-
-
Ortiz-Vega, S.1
Khokhlatchev, A.2
Nedwidek, M.3
Zhang, X.4
Dammann, R.5
Pfeifer, G.P.6
Avruch, J.7
-
13
-
-
18444408077
-
K-Ras mutations and RASSF1A promoter methylation in colorectal cancer
-
Van Engeland, M., Roemen, G. M. J. M., Brink, M., Paehen, M. M. M., Weijenberg, M. P., de Bruïne, A. P., Arends, J. W., van den Brandts, P. A., de Goeij, A. F. P. M., and Herman, J. P. K-Ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene, 21: 3792-3795, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 3792-3795
-
-
Van Engeland, M.1
Roemen, G.M.J.M.2
Brink, M.3
Paehen, M.M.M.4
Weijenberg, M.P.5
De Bruïne, A.P.6
Arends, J.W.7
Van den Brandts, P.A.8
De Goeij, A.F.P.M.9
Herman, J.P.10
-
14
-
-
0029843950
-
Methylation-specific PCR a novel PCR assay for methylation status of CpG islands
-
Herman, J. G., Graff, J. R., Myohanen, S., Nelkin, B. D., and Baylin, S. B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA, 93: 9821-9826, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
15
-
-
0030894182
-
K-Ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small cell lung cancer
-
Fukuyama, Y., Mitsudomi, T., Sugio, K., Ishida, T., Akazawa, K., and Sugimachi, K. K-Ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small cell lung cancer. Br. J. Cancer, 75: 1125-1130, 1997.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1125-1130
-
-
Fukuyama, Y.1
Mitsudomi, T.2
Sugio, K.3
Ishida, T.4
Akazawa, K.5
Sugimachi, K.6
-
16
-
-
0032975370
-
Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small cell lung cancer
-
Graziano, S. L., Gamble, G. P., Newman, N. B., Abbott, L. Z., Rooney, M., Mookherjee, S., Lamb, M. L., Kohman, L. J., and Poiesz, B. Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small cell lung cancer. J. Clin. Oncol., 17: 668-675, 1999.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 668-675
-
-
Graziano, S.L.1
Gamble, G.P.2
Newman, N.B.3
Abbott, L.Z.4
Rooney, M.5
Mookherjee, S.6
Lamb, M.L.7
Kohman, L.J.8
Poiesz, B.9
-
17
-
-
0031776498
-
Prognostic value of loss of heterozygosity and kras2 mutations in lung adenocarcinoma
-
Gregorio, L. D., Manenti, G., Incarbone, M., Pilotti, S., Pastorino, U., Pierotti, M. A., and Dmgani, T. A. Prognostic value of loss of heterozygosity and kras2 mutations in lung adenocarcinoma. Int. J. Cancer, 79: 269-272, 1999.
-
(1999)
Int. J. Cancer
, vol.79
, pp. 269-272
-
-
Gregorio, L.D.1
Manenti, G.2
Incarbone, M.3
Pilotti, S.4
Pastorino, U.5
Pierotti, M.A.6
Dmgani, T.A.7
-
18
-
-
0035992419
-
Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma
-
Tomizawa, Y., Kohno, T., Kondo, H., Otsuka, A., Nishioka, M., Niki, T., Yamada, T., Maeshima, A., Yoshimura, K., Saito, R., Minna, J. D., and Yokota, J. Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma. Clin. Cancer Res., 8: 2362-2368, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 2362-2368
-
-
Tomizawa, Y.1
Kohno, T.2
Kondo, H.3
Otsuka, A.4
Nishioka, M.5
Niki, T.6
Yamada, T.7
Maeshima, A.8
Yoshimura, K.9
Saito, R.10
Minna, J.D.11
Yokota, J.12
-
19
-
-
0036264815
-
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
-
Shivakumar, L., Minna, J., Sakamaki, T., Pestell, R., and White, M. A. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol. Cell. Biol., 22: 4309-4318, 2002.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4309-4318
-
-
Shivakumar, L.1
Minna, J.2
Sakamaki, T.3
Pestell, R.4
White, M.A.5
-
20
-
-
0028152992
-
Induction of cyclin D1 overexpression by activated ras
-
Filmus, J., Robles, A. I., Shi, W., Wong, M. J., Colombo, L. L., and Conti, C. J. Induction of cyclin D1 overexpression by activated ras. Oncogene, 9: 3627-3633, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3627-3633
-
-
Filmus, J.1
Robles, A.I.2
Shi, W.3
Wong, M.J.4
Colombo, L.L.5
Conti, C.J.6
-
21
-
-
0029017456
-
Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH3T3 cells
-
Liu, J-J., Chao, J-R., Jiang, M-C., Ng, S-Y., Yen, J. J-Y., and Yang-Yen, H-F. Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH3T3 cells. Mol. Cell. Biol., 15: 3654-3663, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3654-3663
-
-
Liu, J.-J.1
Chao, J.-R.2
Jiang, M.-C.3
Ng, S.-Y.4
Yen, J.J.-Y.5
Yang-Yen, H.-F.6
-
22
-
-
0030042598
-
Regulation of the cell cycle machinery by oncogenic ras
-
Winston, J. T., Coats, S. R., Wang, Y-Z., and Pledger, W. J. Regulation of the cell cycle machinery by oncogenic ras. Oncogene, 12: 127-134, 1996.
-
(1996)
Oncogene
, vol.12
, pp. 127-134
-
-
Winston, J.T.1
Coats, S.R.2
Wang, Y.-Z.3
Pledger, W.J.4
-
23
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim, S-T., Lim, D-S., Canman, C. E., and Kastan, M. B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem., 274: 37538-37543, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.-T.1
Lim, D.-S.2
Canman, C.E.3
Kastan, M.B.4
-
24
-
-
0037007119
-
Cell signaling: Life or death decisions of Ras proteins
-
Feig, L. A., and Buchsbaum, R. J. Cell signaling: life or death decisions of Ras proteins. Curr. Biol., 12: R259-R261, 2002.
-
(2002)
Curr. Biol.
, vol.12
-
-
Feig, L.A.1
Buchsbaum, R.J.2
|