High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma

Cancer Research

Volumn 61, Issue 10, 2001, Pages 3877-3881

  Lo, Kwok Wai ^a,b   Kwong, Joseph ^a   Hui, Angela Bik Yu ^a   Chan, Sylvia Yat Yee ^a   To, Ka Fai ^a   Chan, Andrew Siu Chung ^b   Chow, Lillian Shuk Nga ^a   Teo, Peter M L ^a,b   Johnson, Philip J ^a,b   Huang, Dolly Poon ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDINE;

ARTICLE; CANCER CELL CULTURE; CHROMOSOME 3P; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; DNA METHYLATION; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT;

CHROMOSOMES, HUMAN, PAIR 3; DNA METHYLATION; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; HUMANS; MUTATION; NASOPHARYNGEAL NEOPLASMS; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0035872408     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Nasopharyngeal carcinoma: An epidemiological approach to carcinogenesis
2. Aetiological factors and pathogenesis
3. High resolution allelotype of microdissected primary nasopharyngeal carcinoma
4. Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridization
5. p16 gene alterations in nasopharyngeal carcinoma
6. Hypermethylation of the p16 gene in nasopharyngeal carcinoma
7. High frequency of chromosome 3p deletion in histologically normal nasopharyngeal epithelia from southern Chinese
8. Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3
9. Detailed deletion mapping on the short arm of chromosome 3 in nasopharyngeal carcinomas
10. Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3
11. Cytogenetics of undifferentiated carcinoma xenografts from southern Chinese
12. Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of nasopharynx
13. Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus
14. Methylation-specific PCR, a novel PCR assay for methylation status of CpG islands
15. Alterations on chromosome 3 in endemic and nonendemic nasopharyngeal carcinoma
16. Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes
17. Involvement of multiple loci on chromosome 3 in renal cell cancer development
18. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes
19. Ras uses the novel tumor suppressor RASSF1 as an effector to medicate apoptosis
20. Substrate specificities and identification of putative substrates of ATM kinase family members