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Volumn 23, Issue 4, 2003, Pages 1151-1158

Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits

Author keywords

Assembly of subunits; Dimer; Glutamate receptor; Ion channel; NMDA; Stoichiometry; Tandem

Indexed keywords

DIMER; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN SUBUNIT;

EID: 0037442813     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-04-01151.2003     Document Type: Article
Times cited : (195)

References (48)
  • 1
    • 0031961764 scopus 로고    scopus 로고
    • Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
    • Anson LC, Chen PE, Wyllie DJ, Colquhoun D, Schoepfer R (1998) Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. J Neurosci 18:581-589.
    • (1998) J Neurosci , vol.18 , pp. 581-589
    • Anson, L.C.1    Chen, P.E.2    Wyllie, D.J.3    Colquhoun, D.4    Schoepfer, R.5
  • 2
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
    • Armstrong N,GouauxE (2000) Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28:165-181.
    • (2000) Neuron , vol.28 , pp. 165-181
    • Armstrong, N.1    Gouaux, E.2
  • 3
    • 0035965267 scopus 로고    scopus 로고
    • Subunit arrangement of γ-aminobutyric acid type A receptors
    • Baumann SW, Baur R, Sigel E (2001) Subunit arrangement of γ-aminobutyric acid type A receptors. J Biol Chem 276:36275-36280.
    • (2001) J Biol Chem , vol.276 , pp. 36275-36280
    • Baumann, S.W.1    Baur, R.2    Sigel, E.3
  • 5
    • 0033178688 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors
    • Bigge CF (1999) Ionotropic glutamate receptors. Curr Opin Chem Biol 3:441-447.
    • (1999) Curr Opin Chem Biol , vol.3 , pp. 441-447
    • Bigge, C.F.1
  • 6
    • 0036582716 scopus 로고    scopus 로고
    • Functional stoichiometry of glutamate receptor desensitization
    • Bowie D, Lange GD (2002) Functional stoichiometry of glutamate receptor desensitization. J Neurosci 22:3392-3403.
    • (2002) J Neurosci , vol.22 , pp. 3392-3403
    • Bowie, D.1    Lange, G.D.2
  • 7
    • 0033576612 scopus 로고    scopus 로고
    • Functional characterization of a potassium-selective prokaryotic glutamate receptor
    • Chen GQ, Cui C, Mayer ML, Gouaux E (1999) Functional characterization of a potassium-selective prokaryotic glutamate receptor. Nature 402:817-821.
    • (1999) Nature , vol.402 , pp. 817-821
    • Chen, G.Q.1    Cui, C.2    Mayer, M.L.3    Gouaux, E.4
  • 8
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, Brickley S, Farrant M (2001) NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11:327-335.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 10
    • 0032514480 scopus 로고    scopus 로고
    • Pore stoichiometry of a voltage-gated chloride channel
    • Fahlke C, Rhodes TH, Desai RR, George Jr AL (1998) Pore stoichiometry of a voltage-gated chloride channel. Nature 394:687-690.
    • (1998) Nature , vol.394 , pp. 687-690
    • Fahlke, C.1    Rhodes, T.H.2    Desai, R.R.3    George A.L., Jr.4
  • 11
    • 0020003862 scopus 로고
    • Desensitization at the frog neuromuscular junction: A biphasic process
    • Feltz A, Trautmann A (1982) Desensitization at the frog neuromuscular junction: a biphasic process. J Physiol (Lond) 322:257-272.
    • (1982) J Physiol (Lond) , vol.322 , pp. 257-272
    • Feltz, A.1    Trautmann, A.2
  • 13
    • 0034681127 scopus 로고    scopus 로고
    • Constraining the subunit order of rod cyclic nucleotide-gated channels reveals a diagonal arrangement of like subunits
    • He Y, Ruiz M, Karpen JW (2000) Constraining the subunit order of rod cyclic nucleotide-gated channels reveals a diagonal arrangement of like subunits. Proc Natl Acad Sci USA 97:895-900.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 895-900
    • He, Y.1    Ruiz, M.2    Karpen, J.W.3
  • 15
    • 0030595368 scopus 로고    scopus 로고
    • The crystal structure of glutamine-binding protein from Escherichia coli
    • Hsiao CD, Sun YJ, Rose J, Wang BC (1996) The crystal structure of glutamine-binding protein from Escherichia coli. J Mol Biol 262:225-242.
    • (1996) J Mol Biol , vol.262 , pp. 225-242
    • Hsiao, C.D.1    Sun, Y.J.2    Rose, J.3    Wang, B.C.4
  • 17
    • 0025362581 scopus 로고
    • Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes
    • Isacoff EY, Jan YN, Jan LY (1990) Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature 345:530-534.
    • (1990) Nature , vol.345 , pp. 530-534
    • Isacoff, E.Y.1    Jan, Y.N.2    Jan, L.Y.3
  • 18
    • 0034114521 scopus 로고    scopus 로고
    • Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties
    • Kohda K, Wang Y, Yuzaki M (2000) Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties. Nat Neurosci 3:315-322.
    • (2000) Nat Neurosci , vol.3 , pp. 315-322
    • Kohda, K.1    Wang, Y.2    Yuzaki, M.3
  • 19
    • 0036236357 scopus 로고    scopus 로고
    • Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors
    • Krupp JJ, Vissel B, Thomas CG, Heinemann SF, Westbrook GL (2002) Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors. Neuropharmacology 42:593-602.
    • (2002) Neuropharmacology , vol.42 , pp. 593-602
    • Krupp, J.J.1    Vissel, B.2    Thomas, C.G.3    Heinemann, S.F.4    Westbrook, G.L.5
  • 21
    • 0032878510 scopus 로고    scopus 로고
    • Oligomerization and ligand-binding properties of the ectodomain of the α-amino-3-hydroxy5-methyl-4-isoxazole propionic acid receptor subunit GluRD
    • Kuusinen A, Abele R, Madden DR, Keinanen K (1999) Oligomerization and ligand-binding properties of the ectodomain of the α-amino-3-hydroxy5-methyl-4-isoxazole propionic acid receptor subunit GluRD. J Biol Chem 274:28937-28943.
    • (1999) J Biol Chem , vol.274 , pp. 28937-28943
    • Kuusinen, A.1    Abele, R.2    Madden, D.R.3    Keinanen, K.4
  • 22
    • 0032523002 scopus 로고    scopus 로고
    • Evidence for a tetrameric structure of recombinant NMDA receptors
    • Laube B, Kuhse J, Betz H (1998) Evidence for a tetrameric structure of recombinant NMDA receptors. J Neurosci 18:2954-2961.
    • (1998) J Neurosci , vol.18 , pp. 2954-2961
    • Laube, B.1    Kuhse, J.2    Betz, H.3
  • 23
    • 0026485457 scopus 로고
    • + channel determined by construction of multimeric cDNAs
    • + channel determined by construction of multimeric cDNAs. Neuron 9:861-871.
    • (1992) Neuron , vol.9 , pp. 861-871
    • Liman, E.R.1    Tytgat, J.2    Hess, P.3
  • 24
    • 0032127530 scopus 로고    scopus 로고
    • Constraining ligandbinding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers
    • Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA (1998) Constraining ligandbinding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron 21:235-248.
    • (1998) Neuron , vol.21 , pp. 235-248
    • Liu, D.T.1    Tibbs, G.R.2    Paoletti, P.3    Siegelbaum, S.A.4
  • 25
    • 0034726717 scopus 로고    scopus 로고
    • Identification of a juxtamembrane segment of the glutamate receptor delta2 subunit required for the plasma membrane localization
    • Matsuda I, Mishina M (2000) Identification of a juxtamembrane segment of the glutamate receptor delta2 subunit required for the plasma membrane localization. Biochem Biophys Res Commun 275:565-571.
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 565-571
    • Matsuda, I.1    Mishina, M.2
  • 28
    • 0033032511 scopus 로고    scopus 로고
    • Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel
    • Morrill JA, MacKinnon R (1999) Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel. J Gen Physiol 114:71-83.
    • (1999) J Gen Physiol , vol.114 , pp. 71-83
    • Morrill, J.A.1    MacKinnon, R.2
  • 29
    • 0031047595 scopus 로고    scopus 로고
    • Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence
    • Premkumar LS, Qin F, Auerbach A (1997) Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence. J Gen Physiol 109:181-189.
    • (1997) J Gen Physiol , vol.109 , pp. 181-189
    • Premkumar, L.S.1    Qin, F.2    Auerbach, A.3
  • 32
    • 0035426114 scopus 로고    scopus 로고
    • Subunit interactions and AMPA receptor desensitization
    • Robert A, Irizarry SN, Hughes TE, Howe JR (2001) Subunit interactions and AMPA receptor desensitization. J Neurosci 21:5574-5586.
    • (2001) J Neurosci , vol.21 , pp. 5574-5586
    • Robert, A.1    Irizarry, S.N.2    Hughes, T.E.3    Howe, J.R.4
  • 33
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund C, Stern -Bach Y, Stevens CF (1998) The tetrameric structure of a glutamate receptor channel. Science 280:1596-1599.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 34
    • 0031017261 scopus 로고    scopus 로고
    • Coupling of permeation and gating in an NMDA-channel pore mutant
    • Schneggenburger R, Ascher P (1997) Coupling of permeation and gating in an NMDA-channel pore mutant. Neuron 18:167-177.
    • (1997) Neuron , vol.18 , pp. 167-177
    • Schneggenburger, R.1    Ascher, P.2
  • 35
    • 0035341508 scopus 로고    scopus 로고
    • An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing
    • Scott DB, Blanpied TA, Swanson GT, Zhang C, Ehlers MD (2001) An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing. J Neurosci 21:3063-3072.
    • (2001) J Neurosci , vol.21 , pp. 3063-3072
    • Scott, D.B.1    Blanpied, T.A.2    Swanson, G.T.3    Zhang, C.4    Ehlers, M.D.5
  • 36
    • 0033860051 scopus 로고    scopus 로고
    • Ligand-gated ion channel interactions with cytoskeletal and signaling proteins
    • Sheng M, Pak DT (2000) Ligand-gated ion channel interactions with cytoskeletal and signaling proteins. Annu Rev Physiol 62:755-778.
    • (2000) Annu Rev Physiol , vol.62 , pp. 755-778
    • Sheng, M.1    Pak, D.T.2
  • 37
    • 0034520590 scopus 로고    scopus 로고
    • PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants
    • Standley S, Roche KW, McCallum J, Sans N, Wenthold RJ (2000) PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants. Neuron 28:887-898.
    • (2000) Neuron , vol.28 , pp. 887-898
    • Standley, S.1    Roche, K.W.2    McCallum, J.3    Sans, N.4    Wenthold, R.J.5
  • 38
    • 0034659803 scopus 로고    scopus 로고
    • C-terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors
    • Steigerwald F, Schulz TW, Schenker LT, Kennedy MB, Seeburg PH, Kohr G (2000) C-terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors. J Neurosci 20:4573-4581.
    • (2000) J Neurosci , vol.20 , pp. 4573-4581
    • Steigerwald, F.1    Schulz, T.W.2    Schenker, L.T.3    Kennedy, M.B.4    Seeburg, P.H.5    Kohr, G.6
  • 39
    • 0027099647 scopus 로고
    • Single-channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native receptors
    • Stern P, Behe P, Schoepfer R, Colquhoun D (1992) Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proc R Soc Lond B Biol Sci 250:271-277.
    • (1992) Proc R Soc Lond B Biol Sci , vol.250 , pp. 271-277
    • Stern, P.1    Behe, P.2    Schoepfer, R.3    Colquhoun, D.4
  • 41
    • 0029957882 scopus 로고    scopus 로고
    • Functional correlation of NMDA receptor E subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum
    • Takahashi T, Feldmeyer D, Suzuki N, Onodera K, Cull-Candy SG, Sakimura K, Mishina M (1996) Functional correlation of NMDA receptor E subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum. J Neurosci 16:4376-4382.
    • (1996) J Neurosci , vol.16 , pp. 4376-4382
    • Takahashi, T.1    Feldmeyer, D.2    Suzuki, N.3    Onodera, K.4    Cull-Candy, S.G.5    Sakimura, K.6    Mishina, M.7
  • 42
  • 43
    • 0032006303 scopus 로고    scopus 로고
    • Glycine-independent NMDA receptor desensitization: Localization of structural determinants
    • Villarroel A, Regalado MP, Lerma J (1998) Glycine-independent NMDA receptor desensitization: localization of structural determinants. Neuron 20:329-339.
    • (1998) Neuron , vol.20 , pp. 329-339
    • Villarroel, A.1    Regalado, M.P.2    Lerma, J.3
  • 44
    • 0028965140 scopus 로고
    • Unraveling the modular design of glutamategated ion channels
    • Wo ZG, Oswald RE (1995) Unraveling the modular design of glutamategated ion channels. Trends Neurosci 18:161-168.
    • (1995) Trends Neurosci , vol.18 , pp. 161-168
    • Wo, Z.G.1    Oswald, R.E.2
  • 45
    • 0001823013 scopus 로고    scopus 로고
    • Single-channel activations and concentration jumps: Comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
    • Wyllie DJ, Behe P, Colquhoun D (1998) Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. J Physiol (Lond) 510:1-18.
    • (1998) J Physiol (Lond) , vol.510 , pp. 1-18
    • Wyllie, D.J.1    Behe, P.2    Colquhoun, D.3
  • 46
    • 0034788270 scopus 로고    scopus 로고
    • An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits
    • Xia H, Hornby ZD, Malenka RC (2001) An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits. Neuropharmacology 41:714-723.
    • (2001) Neuropharmacology , vol.41 , pp. 714-723
    • Xia, H.1    Hornby, Z.D.2    Malenka, R.C.3
  • 47
    • 0029153879 scopus 로고
    • Kinetic properties of NMDA receptors in embryonic Xenopus spinal neurons
    • Zhang Y, Auerbach A (1995) Kinetic properties of NMDA receptors in embryonic Xenopus spinal neurons. J Neurophysiol 74:153-161.
    • (1995) J Neurophysiol , vol.74 , pp. 153-161
    • Zhang, Y.1    Auerbach, A.2
  • 48
    • 0031718345 scopus 로고    scopus 로고
    • Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels
    • Zheng J, Sigworth FJ (1998) Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. J Gen Physiol 112:457-474.
    • (1998) J Gen Physiol , vol.112 , pp. 457-474
    • Zheng, J.1    Sigworth, F.J.2


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