Pyroglutamate-modified amyloid β-peptides - AβN3(pE) - strongly affect cultured neuron and astrocyte survival

Journal of Neurochemistry

Volumn 82, Issue 6, 2002, Pages 1480-1489

  Russo, Claudio ^a   Violani, Elisabetta ^b   Salis, Serena ^a   Venezia, Valentina ^a   Dolcini, Virginia ^a   Damonte, Gianluca ^a   Benatti, Umberto ^a   D'Arrigo, Cristina ^c,d   Patrone, Eligio ^d   Carlo, Pia ^a   Schettini, Gennaro ^a,e  

^a UNIVERSITY OF GENOA   (Italy)

^b C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d CNR   (Italy)

^e CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Alzheimer's disease; Amyloid; Apoptosis; Astrocytes; Neurodegeneration; Pyroglutamate

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; PYROGLUTAMIC ACID;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DISEASE COURSE; DISEASE SEVERITY; DOWN SYNDROME; EMBRYO; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RAT; SENILE PLAQUE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; ASTROCYTES; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; L-LACTATE DEHYDROGENASE; NEURONS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PYRROLIDONECARBOXYLIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 17644443469     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01107.x     Document Type: Article

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