Area/moment and compartmental modeling of pharmacokinetics during pregnancy: Applications to maternal/fetal exposures to corticosteroids in sheep and rats

Pharmaceutical Research

Volumn 21, Issue 12, 2004, Pages 2279-2292

  Samtani, Mahesh N ^a   Schwab, Matthias ^b   Nathanielsz, Peter W ^c   Jusko, William J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Corticosteroid; Fetus; p glycoprotein; Pharmacokinetics; Pregnancy

Indexed keywords

BETAMETHASONE; DEXAMETHASONE;

ANIMAL EXPERIMENT; ARTICLE; COMPARTMENT MODEL; DATA ANALYSIS; DRUG ELIMINATION; DRUG METABOLISM; FEMALE; FETUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; SHEEP; STATISTICAL ANALYSIS; THEORY;

ANIMALS; BETAMETHASONE; DEXAMETHASONE; FEMALE; MATERNAL-FETAL EXCHANGE; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, STATISTICAL; PREGNANCY; RATS; SHEEP;

EID: 17644384418     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-004-7681-7     Document Type: Article

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