Identification of P-glycoprotein mutations causing a loss of steroid recognition and transport

Journal of Biological Chemistry

Volumn 274, Issue 29, 1999, Pages 20318-20327

  Vo, Quang D ^a   Gruol, Donald J ^a  

^a SIDNEY KIMMEL CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COLCHICINE; DACTINOMYCIN; DAUNORUBICIN; DEXAMETHASONE; GLYCOPROTEIN P; PUROMYCIN; STEROID; VINCRISTINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG TRANSPORT; FEMALE; GENE EXPRESSION; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL LINE; DEXAMETHASONE; DNA, COMPLEMENTARY; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTATION; P-GLYCOPROTEIN; PROTEIN BINDING; SEQUENCE HOMOLOGY, NUCLEIC ACID; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE;

EID: 0033575293     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.29.20318     Document Type: Article

References (54)

1. Bourgeois, S., Gruol, D. J., Newby, R. F., and Rajah, F. M. (1993) Mol. Endocrinol. 7, 840-851
2. Gruol, D. J., and Bourgeois, S. (1994) Biochem. Cell Biol. 72, 561-571
3. Gruol, D. J., Zee, M. C., Trotter, J., and Bourgeois, S. (1994) Cancer Res. 54, 3088-3091
4. Gruol, D. J., and Bourgeois, S. (1997) Cancer Res. 57, 720-727
5. Yang, C.-P. H., Cohen, D., Greenberger, L. M., Hsu, S. I.-H., and Horwitz, S. B. (1990) J. Biol. Chem. 265, 10282-10288
6. Qian, X., and Beck, W. T. (1990) J. Biol. Chem. 265, 18753-18756
7. Yang, C.-P. H., Goei DePinho, S., Greenberger, L. M., Arceci, R. J., and Horwitz, S. B. (1989) J. Biol. Chem. 264, 782-788
8. Barnes, K. M., Dickstein, B., Cutler, G. B., Jr., Fojo, T., and Bates, S. E. (1996) Biochemistry 35, 4820-4827
9. Gros, P., Dhir, R., Croop, J., and Talbot, F. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7289-7293
10. Kajiji, S., Talbot, F., Grizzuti, K., Van Dyke-Phillips, V., Agresti, M., Safa, A. R., and Gros, P. (1993) Biochemistry 32, 4185-4194
11. Gottesman, M. M., Hrycyna, C. A., Schoenlein, P. V., Germann, U. A., and Pastan, I. (1995) Annu. Rev. Genet. 29, 607-649
12. Choi, K, Chen, C., Kriegler, M., and Roninson, I. B. (1988) Cell 53, 519-529
13. Devine, S. E., Ling, V., and Melera, P. W. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 4564-4568
14. Chen, G., Duran, G. E., Steger, K. A., Lacayo, N. J., Jaffrezou, J. P., Dumontet, C., and Sikic, B. I. (1997) J. Biol. Chem. 272, 5974-5982
15. Currier, S. J., Ueda, K., Willingham, M. C., Pastan, I., and Gottesman, M. M. (1989) J. Biol. Chem. 284, 14376-14381
16. Currier, S. J., Kane, S. E., Willingham, M. C., Cardarelli, C. O., Pastan, I., and Gottesman, M. M. (1992) J. Biol. Chem. 267, 25153-25159
17. Dhir, R., Grizzuti, K., Kajiji, S., and Gros, P. (1993) Biochemistry 32, 9492-9499
18. Loo, T. W., and Clarke, D. M. (1993) J. Biol. Chem. 268, 3143-3149
19. Loo, T. W., and Clarke, D. M. (1993) J. Biol. Chem. 268, 19965-19972
20. Loo, T. W., and Clarke, D. M. (1994) J. Biol. Chem. 269, 7243-7248
21. Loo, T. W., and Clarke, D. M. (1994) Biochemistry 33, 14049-14057
22. Loo, T. W., and Clarke, D. M. (1996) J. Biol. Chem. 271, 15414-15419
23. Hanna, M., Brault, M., Kwan, T., Kast, C., and Gros, P. (1996) Biochemistry 35, 3625-3635
24. Muller, M., Bakos, E., Welker, E., Varadi, A., Germann, U. A., Gottesman, M. M., Morse, B. S., Roninson, I. B., and Sarkadi, B. (1996) J. Biol. Chem. 271, 1877-1883
25. Loo, T. W., and Clarke, D. M. (1997) J. Biol. Chem. 272, 31945-31948
26. Taguchi, Y., Kino, K., Morishima, M., Komano, T., Kane, S. E., and Ueda, K. (1997) Biochemistry 36, 8883-8889
27. Bakos, E., Klein, I., Welker, E., Szabo, K., Muller, M., Sarkadi, B., and Varadi, A. (1997) Biochem. J. 323, 777-783
28. Hafkemeyer, P., Dey, S., Ambudkar, S. V., Hrycyna, C. A., Pastan, I., and Gottesman, M. M. (1998) Biochemistry 37, 16400-16409
29. Beaudet, L., Urbatsch, I. L., and Gros, P. (1998) Biochemistry 37, 9073-9082
30. Urbatsch, I. L., Beaudet, L., Carrier, I., and Gros, P. (1998) Biochemistry 37, 4592-4602
31. Kwan, T., and Gros, P. (1998) Biochemistry 37, 3337-3350
32. Loo, T. W., and Clarke, D. M. (1998) Methods Enzymol. 292, 480-492
33. Safa, A. R., Stern, R. K., Choi, K., Agresti, M., Tamai, I., Mehta, N. D., and Roninson, I. B. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 7225-7229
34. Harris, A. W., Bankhurst, A. D., Mason, S., and Warner, N. L. (1973) J. Immunol. 110, 431-438
35. Johnson, D. M., Newby, R. F., and Bourgeois, S. (1984) Cancer Res. 44, 2435-2440
36. Gruol, D. J., and Dalton, D. K. (1984) J. Cell. Physiol. 119, 107-118
37. Gruol, D. J., Rajah, F. M., and Bourgeois, S. (1989) Mol. Endocrinol. 3, 2119-2127
38. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 182, 156-159
39. Frohman, M. A. (1990) inPCR Protocols (Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds) 1st Ed., pp. 28-38, Academic Press, Inc., San Diego
40. Wong, G. G., Witek, J. S., Temple, P. A., Wilkens, K. M., Leary, A. C., Luxenberg, D. P., Jones, S. S., Brown, E. L., Kay, R. M., Orr, E. C., Shoemaker, C., Golde, D. W., Kaufman, R. J., Hewick, R. M., Wang, E. A., and Clark, S. C. (1985) Science 228, 810-815
41. Kaufman, R. J., Davies, M. V., Pathak, V. K., and Hershey, J. W. B. (1989) Mol. Cell. Biol. 9, 946-958
42. Kawasaki, E. S. (1990) in PCR Protocols (Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds) 1st Ed., pp. 21-27, Academic Press, Inc., San Diego
43. Lepage, P., Devault, A., and Gros, P. (1993) Mol. Cell. Biol. 13, 7380-7392
44. Gros, P., Croop, J., and Housman, D. (1986) Cell 27, 371-380
45. Devault, A., and Gros, P. (1990) Mol. Cell. Biol. 10, 1652-1663
46. Bruggemann, E. P., Germann, U. A., Gottesman, M. M., and Paatan, I. (1989) J. Biol. Chem. 264, 15483-15488
47. Bruggemann, E. P., Currier, S. J., Gottesman, M. M., and Pastan, I. (1992) J. Biol. Chem. 267, 21020-21026
48. Greenberger, L. M., Yang, C.-P. H., Gindin, E., and Horwitz, S. B. (1990) J. Biol. Chem. 265, 4394-4401
49. Greenberger, L. M. (1993) J. Biol. Chem. 268, 11417-11425
50. Zhang, X., Collins, K. I., and Greenberger, L. M. (1995) J. Biol. Chem. 270, 5441-5448
51. Morris, D. I., Greenberger, L. M., Bruggemann, E. P., Cardarelli, C., Gottesman, M. M., Pastan, I., and Seamon, K. B. (1995) Mol. Pharmacol. 46, 329-337
52. Demmer, A., Thole, H., Kubesch, P., Brandt, T., Raida, M., Fislage, R., and Tummler, B. (1997) J. Biol. Chem. 272, 20913-20919
53. Wu, Q., Bounaud, P. Y., Kuduk, S. D., Yang, C. P., Ojima, I., Horwitz, S. B., and Orr, G. A. (1998) Biochemistry 37, 11272-11279
54. Gruol, D. (1999) Biochem. Pharmacol., in press