Fetal hepatic drug elimination

Pharmacology and Therapeutics

Volumn 84, Issue 3, 1999, Pages 429-445

  Ring, John A ^a   Ghabrial, Hany ^a   Ching, Michael S ^a   Smallwood, Richard A ^a   Morgan, Denis J ^a  

^a NONE

Author keywords

Cytochrome P450; Drug metabolism; Glucuronidation; Human fetal liver; Perfused fetal sheep liver; Sulfation

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 3A7; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE 4 HYDROXYLASE; DIMETHYLNITROSAMINE DEMETHYLASE; ETHOXYRESORUFIN DEETHYLASE; UNCLASSIFIED DRUG;

DRUG CLEARANCE; DRUG GLUCURONIDATION; DRUG SULFATION; ENZYME ACTIVITY; FETUS; FETUS LIVER; HUMAN; IN VITRO STUDY; LIVER BLOOD FLOW; LIVER DEVELOPMENT; LIVER METABOLISM; NONHUMAN; PRIORITY JOURNAL; REVIEW; SHEEP; SPECIES DIFFERENCE;

EID: 0032795066     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(99)00046-7     Document Type: Review

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