Diphenhydramine disposition in the sheep maternal-placental-fetal unit: Gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance

Drug Metabolism and Disposition

Volumn 28, Issue 3, 2000, Pages 279-285

  Kumar, Sanjeev ^a   Tonn, George R ^a   Riggs, K Wayne ^a   Rurak, Dan W ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHENHYDRAMINE; PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISPOSITION; DRUG PROTEIN BINDING; FEMALE; FETOPLACENTAL UNIT; FETUS; GESTATIONAL AGE; NONHUMAN; PLACENTAL TRANSFER; PRIORITY JOURNAL; SHEEP; STEADY STATE; UMBILICAL CORD BLOOD FLOW;

ANIMALS; BLOOD PROTEINS; DIPHENHYDRAMINE; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETUS; GESTATIONAL AGE; HISTAMINE H1 ANTAGONISTS; MATERNAL-FETAL EXCHANGE; METABOLIC CLEARANCE RATE; PLACENTA; PREGNANCY; PROTEIN BINDING; REGIONAL BLOOD FLOW; SHEEP; UMBILICUS;

ANIMALIA; OVIS ARIES;

EID: 0034053363     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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