Antimalarial activity of yingzhaosu A analogues

Journal of Medicinal Chemistry

Volumn 45, Issue 21, 2002, Pages 4732-4736

  Kim, Hye Sook ^a   Begum, Khurshida ^a   Ogura, Naoki ^a   Wataya, Yusuke ^a   Tokuyasu, Takahiro ^b   Masuyama, Araki ^b   Nojima, Masatomo ^b   McCullough, Kevin J ^c  

^a OKAYAMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHINESE DRUG; ETHER DERIVATIVE; HYDROPEROXIDE; UNCLASSIFIED DRUG; YINGZHAOSU A;

ANTIMALARIAL ACTIVITY; ARTICLE; CYCLIZATION; CYTOTOXICITY; DRUG STRUCTURE; NONHUMAN; PLASMODIUM FALCIPARUM; REACTION ANALYSIS;

ANIMALS; ANTIMALARIALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CATALYSIS; CELL LINE; CYCLIZATION; MALARIA; MICE; MICE, INBRED ICR; ONIUM COMPOUNDS; PEROXIDES; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PYRIDINES; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037057574     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020208q     Document Type: Article

References (20)

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17. A part of this work was published in preliminary form. Tokuyasu, T.; Masuyama, A.; Nojima, M.; Kim, H.-S.; Wataya, Y. Synthesis and Anti-malarial Activity of Yingzhaosu A Analogues from Unsaturated Hydroperoxy Acetals. Tetrahedron Lett. 2000, 41, 3145-3146. Tokuyasu, T.; Masuyama, A.; Nojima, M.; McCullough, K. J. Halonium Ion-Mediated Unsaturated Hydroperoxy Acetals. Competition between the Formation of Cyclic Peroxide and the Migration of the Methoxy (or Hydroxy) Group. J. Org. Chem. 2000, 65, 1069-1075.
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