The structure and antimalarial activity of some 1,2,4-trioxanes, 1,2,4,5-tetroxanes, and bicyclic endoperoxides. Implications for the mode of action

Heterocycles

Volumn 52, Issue 3, 2000, Pages 1345-1352

  Jefford, Charles W ^a   Rossier, Jean Claude ^a   Milhous, Wilbur K ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; 1,2,4,5 TETROXANE DERIVATIVE; ENDOPEROXIDE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CYCLIZATION; DRUG MECHANISM; DRUG STRUCTURE; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

EID: 0034163723     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-99-s146     Document Type: Article

References (14)

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10. Trioxanes (7-13) were prepared by a standard method (ref. 5). We thank A. Jaber for preparing a sample of 7.
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