Dispiro-1,2,4,5-tetraoxanes: A New Class of Antimalarial Peroxides

Journal of Medicinal Chemistry

Volumn 35, Issue 16, 1992, Pages 3023-3027

  Vennerstrom, Jonathan L ^a   Fu, Hong Ling ^a   Ellis, William Y ^b   Andersen, Steven L ^b   Gerena, Lucia ^b   Ager, Arba L ^c   Wood, James K ^d  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 DIMETHYL 7,8,15,16 TETRAOXADISPIRO[5.2.5.2]HEXADECANE; ANTIMALARIAL AGENT; ARTEMISININ; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SYNTHESIS; MOUSE; NONHUMAN; PLASMODIUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; ANTIMALARIALS; ETHYLENE OXIDE; MALE; MICE; MOLECULAR STRUCTURE; PEROXIDES; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SPIRO COMPOUNDS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026746330     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00094a015     Document Type: Article

References (40)

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