Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes

Journal of Medicinal Chemistry

Volumn 44, Issue 14, 2001, Pages 2357-2361

  Kim, H S ^a   Nagai, Y ^a   Ono, K ^a   Begum, K ^a   Wataya, Y ^a   Hamada, Y ^b   Tsuchiya, K ^b   Masuyama, A ^b   Nojima, M ^b   McCullough, K J ^c  

^a OKAYAMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,6,7 TETRAOXASPIRO[7.11]NONADECANE; ARTEMISININ; CYCLOALKANE DERIVATIVE; PEROXIDE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; MOUSE; NONHUMAN; SYNTHESIS;

ANIMALS; ANTIMALARIALS; CESIUM; CYCLIZATION; DRUG EVALUATION, PRECLINICAL; HETEROCYCLIC COMPOUNDS, 2-RING; HYDROXIDES; MALARIA; MICE; OXIDES; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SILVER COMPOUNDS; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035811454     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010026g     Document Type: Article

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