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Volumn 267, Issue 2, 2000, Pages 434-449

Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysis is not acutely dependent on the activity of anaphase-promoting complex

Author keywords

Anaphase promoting complex; Cdc20; Cell cycle; Proteolysis; Yeast

Indexed keywords

CELL CYCLE PROTEIN; CYCLINE; LIGASE; PROTEASOME; UBIQUITIN;

EID: 0033969432     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01014.x     Document Type: Article
Times cited : (21)

References (42)
  • 1
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
    • 1. Irniger, S., Piatti, S., Michaelis, C. & Nasmyth, K. (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-277.
    • (1995) Cell , vol.81 , pp. 269-277
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 2
    • 0029004815 scopus 로고
    • A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
    • 2. King, R.W., Peters, J.-M., Tugendreich, S., Rolfe, M., Heiter, P. & Kirschner, M.W. (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.W.1    Peters, J.-M.2    Tugendreich, S.3    Rolfe, M.4    Heiter, P.5    Kirschner, M.W.6
  • 3
    • 0029025606 scopus 로고    scopus 로고
    • The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
    • 3. Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F.C., Ruderman, J.V. & Hershko. A. (1997) The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6, 185-198.
    • (1997) Mol. Biol. Cell , vol.6 , pp. 185-198
    • Sudakin, V.1    Ganoth, D.2    Dahan, A.3    Heller, H.4    Hershko, J.5    Luca, F.C.6    Ruderman, J.V.7    Hershko, A.8
  • 4
    • 0029028237 scopus 로고
    • CDC27Hs colocalizes with CDC16Hs to the centromere and mitotic spindle and is essential for the metaphase to anaphase transition
    • 4. Tugendreich, S., Tomkiel, J., Earnshaw, W. & Hieter, P. (1995) CDC27Hs colocalizes with CDC16Hs to the centromere and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81, 261-268.
    • (1995) Cell , vol.81 , pp. 261-268
    • Tugendreich, S.1    Tomkiel, J.2    Earnshaw, W.3    Hieter, P.4
  • 5
    • 0343829343 scopus 로고    scopus 로고
    • Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae
    • 5. Zachariae, W., Shin, TH., Galova, M., Obermaier, B. & Nasmyth, K. (1996) Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science 274, 1201-1204.
    • (1996) Science , vol.274 , pp. 1201-1204
    • Zachariae, W.1    Shin, T.H.2    Galova, M.3    Obermaier, B.4    Nasmyth, K.5
  • 6
    • 0032549115 scopus 로고    scopus 로고
    • Mass spectrometric analysis of the anaphase promoting complex from budding yeast: Identification of a subunit related to cullins
    • 6. Zachariae, W., Shevchenko, A., Andrews, P.D., Stark, M.J.R., Mann, M. & Nasmyth, K. (1998) Mass spectrometric analysis of the anaphase promoting complex from budding yeast: identification of a subunit related to cullins. Science 279, 1216-1219.
    • (1998) Science , Issue.279 , pp. 1216-1219
    • Zachariae, W.1    Shevchenko, A.2    Andrews, P.D.3    Stark, M.J.R.4    Mann, M.5    Nasmyth, K.6
  • 7
    • 0028168867 scopus 로고
    • Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis
    • 7. Lamb, J.R., Michaud, W.A., Sikorski, R.S. & Heiter, P.A. (1994) Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. EMBO J. 13, 4321-4328.
    • (1994) EMBO J. , vol.13 , pp. 4321-4328
    • Lamb, J.R.1    Michaud, W.A.2    Sikorski, R.S.3    Heiter, P.A.4
  • 8
    • 0030448251 scopus 로고    scopus 로고
    • Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inihibitor Pds1p
    • 8. Cohen-Fix, O., Peters, J.-M., Kirschner, M.W. & Koshland, D. (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inihibitor Pds1p. Genes Dev. 10, 3081-3093.
    • (1996) Genes Dev. , vol.10 , pp. 3081-3093
    • Cohen-Fix, O.1    Peters, J.-M.2    Kirschner, M.W.3    Koshland, D.4
  • 9
    • 0030885925 scopus 로고    scopus 로고
    • Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
    • 9. Michaelis, C., Ciosk, R. & Nasmyth, K. (1997) Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell 91, 35-45.
    • (1997) Cell , vol.91 , pp. 35-45
    • Michaelis, C.1    Ciosk, R.2    Nasmyth, K.3
  • 10
    • 0029997447 scopus 로고    scopus 로고
    • Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae
    • 10. Yamamoto, A., Guacci, V. & Koshland, D. (1996a) Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J. Cell Biol. 133, 85-97.
    • (1996) J. Cell Biol. , vol.133 , pp. 85-97
    • Yamamoto, A.1    Guacci, V.2    Koshland, D.3
  • 11
    • 0029960782 scopus 로고    scopus 로고
    • Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathways
    • 11. Yamamoto, A., Guacci, V. & Koshland, D. (1996b) Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathways. J. Cell Biol. 133, 99-110.
    • (1996) J. Cell Biol. , vol.133 , pp. 99-110
    • Yamamoto, A.1    Guacci, V.2    Koshland, D.3
  • 12
    • 0030839209 scopus 로고    scopus 로고
    • The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase
    • 12. Irniger, S. & Nasmyth, K. (1997) The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. J. Cell Sci. 110, 1523-1531.
    • (1997) J. Cell Sci. , vol.110 , pp. 1523-1531
    • Irniger, S.1    Nasmyth, K.2
  • 13
    • 0031055137 scopus 로고    scopus 로고
    • APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle
    • 13. Juang, Y.L., Huang, J., Peters, J.-M., McLaughlin, M.E., Tai, C.Y. & Pellman, D. (1997) APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science 275, 1311-1314.
    • (1997) Science , vol.275 , pp. 1311-1314
    • Juang, Y.L.1    Huang, J.2    Peters, J.-M.3    McLaughlin, M.E.4    Tai, C.Y.5    Pellman, D.6
  • 14
    • 0015847513 scopus 로고
    • Genetic control of cell division cycle in yeast. V. Genetic analysis of cdc mutants
    • 14. Hartwell, L.H., Mortimer, R.K., Culotti, J. & Culotti, M. (1973) Genetic control of cell division cycle in yeast. V. Genetic analysis of cdc mutants. Genetics 74, 267-286.
    • (1973) Genetics , vol.74 , pp. 267-286
    • Hartwell, L.H.1    Mortimer, R.K.2    Culotti, J.3    Culotti, M.4
  • 15
    • 0025993769 scopus 로고
    • The CDC20 gene product of Saccharomyces cerevisiae, a β-transducin homolog, is required for a subset of microtubule-dependent cellular processes
    • 15. Sethi, N., Monteagudo, C., Koshland, D., Hogan, E. & Burke, D. (1991) The CDC20 gene product of Saccharomyces cerevisiae, a β-transducin homolog, is required for a subset of microtubule-dependent cellular processes. Mol. Cell. Biol. 11, 5592-5602.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5592-5602
    • Sethi, N.1    Monteagudo, C.2    Koshland, D.3    Hogan, E.4    Burke, D.5
  • 16
    • 0030874434 scopus 로고    scopus 로고
    • Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae
    • 16. O'Toole, E.T., Mastronarde, D.N., Giddings, T.H. Jr, Winey, M., Burke, D. & McIntosh, J.R. (1997) Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae. Mol. Biol., Cell 8, 1-11.
    • (1997) Mol. Biol., Cell , vol.8 , pp. 1-11
    • O'Toole, E.T.1    Mastronarde, D.N.2    Giddings T.H., Jr.3    Winey, M.4    Burke, D.5    McIntosh, J.R.6
  • 17
    • 0001598759 scopus 로고    scopus 로고
    • Cdc20 is essential for APC-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast
    • 17. Lim, H.H.P.-Y., Goh, P.-Y. & Surana, U. (1998) Cdc20 is essential for APC-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast. Curr. Biol 8, 231-234.
    • (1998) Curr. Biol , vol.8 , pp. 231-234
    • Lim, H.H.P.-Y.1    Goh, P.-Y.2    Surana, U.3
  • 18
    • 0030693087 scopus 로고    scopus 로고
    • CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
    • 18. Visintin, R., Prinz, S. & Amon. A. (1997) CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278, 460-463.
    • (1997) Science , vol.278 , pp. 460-463
    • Visintin, R.1    Prinz, S.2    Amon, A.3
  • 19
    • 0030738748 scopus 로고    scopus 로고
    • Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
    • 19. Schwab, M., Lutum, A.S. & Seufert, W. (1997) Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90, 683-693.
    • (1997) Cell , vol.90 , pp. 683-693
    • Schwab, M.1    Lutum, A.S.2    Seufert, W.3
  • 20
    • 0031038678 scopus 로고    scopus 로고
    • A fission yeast homolog of CDC20/p55CDC/ Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2
    • 20. Matsumoto, T. (1997) A fission yeast homolog of CDC20/p55CDC/ Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2. Mol. Cell. Biol. 17, 742-750.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 742-750
    • Matsumoto, T.1
  • 21
    • 0028958186 scopus 로고
    • The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae
    • 21. Dawson, I.A., Roth, S. & Artavanis-Tsakonas, S. (1995) The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J. Cell Biol. 129, 725-737.
    • (1995) J. Cell Biol. , vol.129 , pp. 725-737
    • Dawson, I.A.1    Roth, S.2    Artavanis-Tsakonas, S.3
  • 22
    • 0029165112 scopus 로고
    • Exit from mitosis is regulated by Drosophila Fizzy and the sequential destruction of cyclins A, B and B3
    • 22. Sigrist, S.J., Jacobs, H., Stratmann, R. & Lehner, C.F. (1995) Exit from mitosis is regulated by Drosophila Fizzy and the sequential destruction of cyclins A, B and B3. EMBO J. 14, 4827-4838.
    • (1995) EMBO J. , vol.14 , pp. 4827-4838
    • Sigrist, S.J.1    Jacobs, H.2    Stratmann, R.3    Lehner, C.F.4
  • 23
    • 0030835478 scopus 로고    scopus 로고
    • Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles
    • 23. Sigrist, S.J. & Lehner, C.F. (1997) Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell 90, 671-681.
    • (1997) Cell , vol.90 , pp. 671-681
    • Sigrist, S.J.1    Lehner, C.F.2
  • 24
    • 0028256410 scopus 로고
    • A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4
    • 24. Weinstein, J., Jacobsen, EW., Hsu-Chen, J., Wu, T. & Baum, L.G. (1994) A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4. Mol. Cell. Biol. 14, 3350-3363.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3350-3363
    • Weinstein, J.1    Jacobsen, E.W.2    Hsu-Chen, J.3    Wu, T.4    Baum, L.G.5
  • 25
    • 0032473568 scopus 로고    scopus 로고
    • The Polo-like kinase Cdc5 and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
    • 25. Shirayama, M., Zachariae, W., Ciosk, R. & Nasmyth, K. (1998) The Polo-like kinase Cdc5 and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J. 17, 1336-1349.
    • (1998) EMBO J. , vol.17 , pp. 1336-1349
    • Shirayama, M.1    Zachariae, W.2    Ciosk, R.3    Nasmyth, K.4
  • 26
    • 0031991880 scopus 로고    scopus 로고
    • PKA and MPF-activated Polo-like kinase regulate anaphase-promoting complex activity and mitotic progression
    • 26. Kotani, S., Tugendreich, S., Fujii, M., Jorgensen, P.-M., Watanabe, N., Hoog, C., Mieter, P. & Todokoro, K. (1998) PKA and MPF-activated Polo-like kinase regulate anaphase-promoting complex activity and mitotic progression. Mol. Cell 1, 371-380.
    • (1998) Mol. Cell , vol.1 , pp. 371-380
    • Kotani, S.1    Tugendreich, S.2    Fujii, M.3    Jorgensen, P.-M.4    Watanabe, N.5    Hoog, C.6    Mieter, P.7    Todokoro, K.8
  • 27
    • 0032254350 scopus 로고    scopus 로고
    • The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation
    • 27. Visintin, R., Craig, K., Hwang, E.S., Prinz, S., Tyres, M. & Amon, A. (1998) The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol. Cell 2, 709-718.
    • (1998) Mol. Cell , vol.2 , pp. 709-718
    • Visintin, R.1    Craig, K.2    Hwang, E.S.3    Prinz, S.4    Tyres, M.5    Amon, A.6
  • 28
    • 0030695025 scopus 로고    scopus 로고
    • A complex of Cdc4p, Skp1p, and Cdc53/cullin catalyzes ubiquiti-nation of the phosphorylated CDK inhibitor Sic1p
    • 28. Feldman, R.M.R., Cornell, C.C., Kaplan, K.B. & Deshaies, R.J. (1997) A complex of Cdc4p, Skp1p, and Cdc53/cullin catalyzes ubiquiti-nation of the phosphorylated CDK inhibitor Sic1p. Cell 91, 221-230.
    • (1997) Cell , vol.91 , pp. 221-230
    • Feldman, R.M.R.1    Cornell, C.C.2    Kaplan, K.B.3    Deshaies, R.J.4
  • 30
    • 0030662523 scopus 로고    scopus 로고
    • F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
    • 30. Skowyra, D., Craig, K.L., Tyers, M., Elledge, S.J. & Harper, J.W. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91, 209-219.
    • (1997) Cell , vol.91 , pp. 209-219
    • Skowyra, D.1    Craig, K.L.2    Tyers, M.3    Elledge, S.J.4    Harper, J.W.5
  • 31
    • 0030612012 scopus 로고    scopus 로고
    • Phosphorylation of Siclp by G1 Cdk required for its degradation and entry into S phase
    • 31. Verma, R., Annan, R.S., Huddleston, M.J., Carr, S.A., Reynard, G. & Deshaies, R.J. (1997) Phosphorylation of Siclp by G1 Cdk required for its degradation and entry into S phase. Science 278, 455-459.
    • (1997) Science , vol.278 , pp. 455-459
    • Verma, R.1    Annan, R.S.2    Huddleston, M.J.3    Carr, S.A.4    Reynard, G.5    Deshaies, R.J.6
  • 32
    • 0030868430 scopus 로고    scopus 로고
    • The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
    • 32. Drury, L.S., Perkins, G. & Diffley, J.F.X. (1997) The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J. 16, 5966-5976.
    • (1997) EMBO J. , vol.16 , pp. 5966-5976
    • Drury, L.S.1    Perkins, G.2    Diffley, J.F.X.3
  • 33
    • 0029761435 scopus 로고    scopus 로고
    • Activation of S-phase-promoting CDKs in late G1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast
    • 33. Piatti, S., Bohm, T., Cocker, J.H., Diffley, J.F.X. & Nasmyth, K. (1996) Activation of S-phase-promoting CDKs in late G1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast. Genes Dev. 10, 1516-1531.
    • (1996) Genes Dev. , vol.10 , pp. 1516-1531
    • Piatti, S.1    Bohm, T.2    Cocker, J.H.3    Diffley, J.F.X.4    Nasmyth, K.5
  • 34
    • 10244264687 scopus 로고    scopus 로고
    • Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28
    • 34. Lim, H.H., Goh, P.-Y. & Surana, U. (1996) Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28. Mol. Cell. Biol. 16, 6385-6397.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6385-6397
    • Lim, H.H.1    Goh, P.-Y.2    Surana, U.3
  • 35
    • 0025753691 scopus 로고
    • A positive feedback loop controlling CLN1 and CLN2 gene expression at the start of yeast cell cycle
    • 35. Cross, F. & Tinkelenberg, A.H. (1991) A positive feedback loop controlling CLN1 and CLN2 gene expression at the start of yeast cell cycle. Cell 65, 875-883.
    • (1991) Cell , vol.65 , pp. 875-883
    • Cross, F.1    Tinkelenberg, A.H.2
  • 36
    • 0025764225 scopus 로고
    • A general approach to the isolation of cell cycle-regulated genes in the budding yeast Saccharomyces cerevisiae
    • 36. Price, C., Nasmyth, K. & Schuster, T. (1991) A general approach to the isolation of cell cycle-regulated genes in the budding yeast Saccharomyces cerevisiae. J. Mol. Biol. 218, 543-556.
    • (1991) J. Mol. Biol. , vol.218 , pp. 543-556
    • Price, C.1    Nasmyth, K.2    Schuster, T.3
  • 37
    • 0021369651 scopus 로고
    • Structural arrangement of tubulin and actin during the cell cycle of Saccharomyces
    • 37. Kilmartin, J.V.K. & Adams, A.M.E. (1984) Structural arrangement of tubulin and actin during the cell cycle of Saccharomyces. J. Cell Biol. 98, 922-933.
    • (1984) J. Cell Biol. , vol.98 , pp. 922-933
    • Kilmartin, J.V.K.1    Adams, A.M.E.2
  • 38
    • 0028240049 scopus 로고
    • Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until activation of G1 cyclins in the next cycle
    • 38. Amon, A., Irniger, S. & Nasmyth, K. (1994) Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until activation of G1 cyclins in the next cycle. Cell 77, 1037-1050.
    • (1994) Cell , vol.77 , pp. 1037-1050
    • Amon, A.1    Irniger, S.2    Nasmyth, K.3
  • 39
    • 0027158083 scopus 로고
    • Destruction of the CDC28/CLB mitotic kinase is not required for metaphase to anaphase transition in budding yeast
    • 39. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B. & Nasmyth, K. (1993) Destruction of the CDC28/CLB mitotic kinase is not required for metaphase to anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
    • (1993) EMBO J. , vol.12 , pp. 1969-1978
    • Surana, U.1    Amon, A.2    Dowzer, C.3    McGrew, J.4    Byers, B.5    Nasmyth, K.6
  • 40
    • 0032543552 scopus 로고    scopus 로고
    • The regulation of Cdc20 proteolysis reveals a role for the APC components Cdc23 and Cdc27 during S phase and early mitosis
    • 40. Prinz, S., Huang, E.S., Visintin, R. & Amon, A. (1998) The regulation of Cdc20 proteolysis reveals a role for the APC components Cdc23 and Cdc27 during S phase and early mitosis. Curr. Biol. 8, 750-760.
    • (1998) Curr. Biol. , vol.8 , pp. 750-760
    • Prinz, S.1    Huang, E.S.2    Visintin, R.3    Amon, A.4
  • 41
    • 0027444947 scopus 로고
    • S. Cerevisiae 26S protease mutants arrest cell division in G2/metaphase
    • 41. Ghislain, M., Udvardy, A. & Mann, C. (1993) S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature 366, 358-362.
    • (1993) Nature , vol.366 , pp. 358-362
    • Ghislain, M.1    Udvardy, A.2    Mann, C.3


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