Pds1p of budding yeast has dual roles: Inhibition of anaphase initiation and regulation of mitotic exit

Genes and Development

Volumn 13, Issue 15, 1999, Pages 1950-1959

  Cohen Fix, Orna ^a   Koshland, Doug ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Budding yeast; Cyclin degradation; Metaphase to anaphase transition; Mitosis

Indexed keywords

CELL CYCLE PROTEIN; CYCLINE; INHIBITOR PROTEIN;

ANAPHASE; ARTICLE; METAPHASE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; YEAST;

SACCHAROMYCETALES;

EID: 0033180066     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.15.1950     Document Type: Article

References (37)

1. Amon, A. 1997. Regulation of B-type cyclin proteolysis by Cdc28-associated kinases in budding yeast. EMBO J. 16: 2693-2702.
2. _. 1999. The spindle checkpoint. Curr. Opin. Genet. Dev. 9: 69-75.
3. Amon, A., S. Imiger, and K. Nasmyth. 1994. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell 77: 1037-1050.
4. Ciosk, R., W. Zachariae, C. Michaelis, A. Shevchenko, M. Mann, and K. Nasmyth. 1998. AnESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93: 1067-1076.
5. Cohen-Fix, O. and D. Koshland. 1997a. The anaphase inhibitor of Saccharomyces cerevisiae Pds1p is a target of the DNA damage checkpoint pathway. Pioc. Natl. Acad. Sci. 94: 14361-14366.
6. _. 1997b. The metaphase-to-anaphase transition: Avoiding a mid-life crisis. Curr. Opin. Cell. Biol. 9: 800-806.
7. Cohen-Fix, O., J.M. Peters, M.W. Kirschner, and D. Koshland. 1996. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pdslp. Genes & Dev. 10: 3081-3093.
8. Fang, G., H. Yu, and M.W. Kirschner. 1998. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes & Dev. 12: 1871-1883.
9. Funabiki, H., K. Kumada, and M. Yanagida. 1996a. Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J. 15: 6617-6628.
10. Funabiki, H., H. Yamano, K. Kumada, K. Nagao, T. Hunt, and M. Yanagida. 1996b. Cut2 proteolysis required for sister-chromatid seperation in fission yeast. Nature 381: 438-441.
11. Glotzer, M., A.W. Murray, and M.W. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349: 132-138.
12. Jaspersen, S.L., J.F. Charles, and D.O. Morgan. 1999. Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. Curr. Biol 9: 227-236.
13. Juang, Y.L., J. Huang, J.M. Peters, M.E. McLaughlin, C.Y. Tai, and D. Pellman. 1997. APC-mediated proteolysis of Asel and the morphogenesis of the mitotic spindle. Science 275: 1311-1314.
14. King, R.W., J.M. Peters, S. Tugendreich, M. Rolfe, P. Hieter, and M.W. Kirschner. 1995. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81: 279-288.
15. Kumada, K., T. Nakamura, K. Nagao, H. Funabiki, T. Nakagawa, and M. Yanagida. 1998. Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis. Curr. Biol. 8: 633-641.
16. Li, Y., C. Gorbea, D. Mahaffey, M. Rechsteiner, and R. Benezra. 1997. MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc. Natl. Acad. Sci. 94: 12431-12436.
17. McGrew, J.T., L. Goetsch, B. Byers, and P. Baum. 1992. Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae. Mol. Biol. Cell 3: 1443-1454.
18. Michaelis, C., R. Ciosk, and K. Nasmyth. 1997. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids. Cell 91: 35-45.
19. Morgan, D.O. 1999. Regulation of APC and the exit from mitosis. Nat. Cell Biol. 1: E47-E53.
20. Palmer, R.E., M. Koval, and D. Koshland. 1989. The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae. J. Cell Biol. 109: 3355-3366.
21. Peters, J.M. 1998. SCF and APC: The yin and yang of cell cycle regulated proteolysis. Curr. Opin. Cell. Biol. 10: 759-768.
22. Schwab, M., A.S. Lutum, and W. Seufert. 1997. Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90: 683-693.
23. Schwob, E., T. Bohm, M.D. Mendenhall, and K. Nasmyth. 1994. The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-244.
24. Shou, W., J.H. Seol, A. Shevchenko, C. Baskerville, D. Moazed, Z.W. Chen, J. Jang, H. Charbonneau, and R.J. Deshaies. 1999. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97: 233-244.
25. Straight, A.F., W.F. Marshall, J.W. Sedat, and A.W. Murray. 1997. Mitosis in living budding yeast: Anaphase A but no metaphase plate. Science 277: 574-578.
26. Sudakin, V., D. Ganoth, A. Dahan, H. Heller, J. Hershko, F.C. Luca, J.V. Ruderman, and A. Hershko. 1995. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6: 185-197.
27. Surana, U., A. Amon, C. Dowzer, J. McGrew, B. Byers, and K. Nasmyth. 1993. Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12: 1969-1978.
28. Tinker-Kulberg, R.L. and D.O. Morgan. 1999. Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and following DNA damage. Genes & Dev. (This issue).
29. Visintin, R., S. Prinz, and A. Amon. 1997. CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis. Science 278: 460-463.
30. Visintin, R., K. Craig, E.S. Hwang, S. Prinz, M. Tyers, and A. Amon. 1998. The phosphatase Cdcl4 triggers mitotic exit by reversal of Cdk- dependent phosphorylation. Mol. Cell 2: 709-718.
31. Visintin, R., E.S. Hwang, and A. Amon. 1999. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus . Nature 398: 818-823.
32. Yamamoto, A., V. Guacci, and D. Koshland. 1996a. Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J. Cell Biol. 133: 85-97.
33. _. 1996b. Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J. Cell Biol. 133: 99-110.
34. Yamano, H., C. Tsurumi, J. Cannon, and T. Hunt. 1998. The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: Defining the D-box receptor. EMBO J. 17: 5670-5678.
35. Yu, H., J.M. Peters, R.W. King, A.M. Page, P. Hieter, and M.W. Kirschner. 1998. Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science 279: 1219-1222.
36. Zachariae, W., M. Schwab, K. Nasmyth, and W. Seufert. 1998a. Control of cyclin ubiquitination by CDK-regulated binding of Hctl to the anaphase promoting complex. Science 282: 1721-1724.
37. Zachariae, W., A. Shevchenko, P.D. Andrews, R. Ciosk, M. Galova, M.J. Stark, M. Mann, and K. Nasmyth. 1998b. Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins. Science 279: 1216-1219.