Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints

Cell

Volumn 107, Issue 5, 2001, Pages 655-665

  Hu, Fenghua ^a   Wang, Yanchang ^a   Liu, Dou ^a   Li, Yumei ^a   Qin, Jun ^a   Elledge, Stephen J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN BFA1; PROTEIN BUB2; PROTEIN CDC5; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA DAMAGE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION;

EID: 0035977126     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00580-3     Document Type: Article

References (41)

1. The surveillance mechanism of the spindle position checkpoint in yeast
2. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage
3. Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast
4. A mechanism for coupling exit from mitosis to partitioning of the nucleus
5. The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain
6. Anaphase spindle position is monitored by the BUB2 checkpoint
7. The Polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae
8. Cell cycle regulation of the Saccharomyces cerevisiae polo-like kinase cdc5p
9. Heat-inducible degron: A method for constructing temperature-sensitive mutants
10. A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast
11. Bypass of the requirement for cdc16p GAP function in Schizosaccharomyces pombe by mutation of the septation initiation network genes
12. Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2
13. Byr4 and Cdc16 form a two-component GTPase-activating protein for the Spg1 GTPase that controls septation in fission yeast
14. RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast
15. Polo-like kinases: A team that plays throughout mitosis
16. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
17. A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae
18. Uninterrupted MCM2-7 function required for DNA replication fork progression
19. Order of function of the budding-yeast mitotic exit-network proteins Tem1, Cdc15, Mob1, Dbf2, and Cdc5
20. The Bub2-dependent mitotic pathway in yeast acts every cell cycle and regulates cytokinesis
21. Bifurcation of the mitotic checkpoint pathway in budding yeast
22. Feedback control of mitosis in budding yeast
23. The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes
24. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
25. Regulation of the APC and the exit from mitosis
26. A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration
27. Polo-like kinases: Positive regulators of cell division from start to finish
28. Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion
29. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
30. The Bub2p spindle checkpoint links nuclear migration with mitotic exit
31. Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
32. The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
33. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
34. A novel function of Saccharomyces cerevisiae CDC5 in cytokinesis
35. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization
36. The role of Plo1 kinase in mitotic commitment and septation in Schizosaccharomyces pombe
37. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation
38. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
39. The Bfa1/Bub2 GAP complex comprises universal checkpoint required to prevent mitotic exit
40. Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function
41. The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint