Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor α subunit: Effects on channel gating and regulation by ethanol

British Journal of Pharmacology

Volumn 131, Issue 2, 2000, Pages 296-302

  Ueno, Susumu ^a,b   Lin, Audrey ^c,d   Nikolaeva, Natalia ^c   Trudell, James R ^e   Mihic, S John ^a,f   Harris, R Adron ^a   Harrison, Neil L ^g  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c UNIVERSITY OF CHICAGO   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e STANFORD UNIVERSITY   (United States)

^f WAKE FOREST SCHOOL OF MEDICINE   (United States)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Ethanol; GABA(A) receptor; Scanning mutagenesis; Xenopus oocytes; subunit

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ALCOHOL; AMINO ACID; ANESTHETIC AGENT; BICUCULLINE; PICROTOXIN; RECEPTOR SUBTYPE; TRYPTOPHAN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE MUTATION; MUTAGENESIS; NEUROTRANSMISSION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS;

EID: 0033778416     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703504     Document Type: Article

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