State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor: Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the α subunit

Journal of General Physiology

Volumn 111, Issue 6, 1998, Pages 717-739

  Pascual, Juan M ^a   Karlin, Arthur ^a,b  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Conductance; Gate; Ion selectivity; Reaction kinetics; Sulfhydryl

Indexed keywords

ACETYLCHOLINE; CHOLINERGIC RECEPTOR; CYSTEINE; ION CHANNEL; SULFONIC ACID DERIVATIVE; THIOL DERIVATIVE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CHANNEL GATING; CHEMICAL REACTION KINETICS; ELECTRIC POTENTIAL; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; REACTION TIME; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; SKELETAL MUSCLE;

ALGORITHMS; ANIMALS; CYSTEINE; ELECTROCHEMISTRY; ION CHANNELS; KINETICS; MEMBRANE POTENTIALS; MICE; OOCYTES; RECEPTORS, CHOLINERGIC; THIOSULFATES; XENOPUS LAEVIS;

EID: 0031781630     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.111.6.717     Document Type: Article

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