-
2
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature. 406:2000;782-787.
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
3
-
-
0029987839
-
The instructive role of innate immunity in the acquired immune response
-
Fearon D.T., Locksley R.M. The instructive role of innate immunity in the acquired immune response. Science. 272:1996;50-53.
-
(1996)
Science
, vol.272
, pp. 50-53
-
-
Fearon, D.T.1
Locksley, R.M.2
-
4
-
-
0028965644
-
Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
-
Ulevitch R.J., Tobias P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:1995;437-457.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 437-457
-
-
Ulevitch, R.J.1
Tobias, P.S.2
-
5
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright S.D., Ramos R.A., Tobias P.S., Ulevitch R.J., Mathison J.C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249:1990;1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
6
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., Janeway C.A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway C.A., Jr.3
-
7
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R., Akashi S., Ogata H., Nagai Y., Fukudome K.et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1999;1777-1782.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
-
8
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann R.R., Leong S.R., Flaggs G.W., Gray P.W., Wright S.D.et al. Structure and function of lipopolysaccharide binding protein. Science. 249:1990;1429-1431.
-
(1990)
Science
, vol.249
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
-
9
-
-
0029919991
-
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice
-
Haziot A., Ferrero E., Kontgen F., Hijiya N., Yamamoto S.et al. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity. 4:1996;407-414.
-
(1996)
Immunity
, vol.4
, pp. 407-414
-
-
Haziot, A.1
Ferrero, E.2
Kontgen, F.3
Hijiya, N.4
Yamamoto, S.5
-
10
-
-
0028501020
-
CD14 is a pattern recognition receptor
-
Pugin J., Heumann I.D., Tomasz A., Kravchenko V.V., Akamatsu Y.et al. CD14 is a pattern recognition receptor. Immunity. 1:1994;509-516.
-
(1994)
Immunity
, vol.1
, pp. 509-516
-
-
Pugin, J.1
Heumann, I.D.2
Tomasz, A.3
Kravchenko, V.V.4
Akamatsu, Y.5
-
11
-
-
0032544343
-
Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide
-
Wang P.Y., Kitchens R.L., Munford R.S. Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide. J. Biol. Chem. 273:1998;24309-24313.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24309-24313
-
-
Wang, P.Y.1
Kitchens, R.L.2
Munford, R.S.3
-
12
-
-
0032473968
-
Human CD14 mediates recognition and phagocytosis of apoptotic cells
-
Devitt A., Moffatt O.D., Raykundalia C., Capra J.D., Simmons D.L.et al. Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature. 392:1998;505-509.
-
(1998)
Nature
, vol.392
, pp. 505-509
-
-
Devitt, A.1
Moffatt, O.D.2
Raykundalia, C.3
Capra, J.D.4
Simmons, D.L.5
-
13
-
-
0028981285
-
CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition
-
Delude R.L., Savedra R. Jr., Zhao H., Thieringer R., Yamamoto S.et al. CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition. Proc. Natl. Acad. Sci. U. S. A. 92:1995;9288-9292.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 9288-9292
-
-
Delude, R.L.1
Savedra R., Jr.2
Zhao, H.3
Thieringer, R.4
Yamamoto, S.5
-
14
-
-
0026653049
-
Lipopolysaccharide antagonists
-
Lynn W.A., Golenbock D.T. Lipopolysaccharide antagonists. Immunol. Today. 13:1992;271-276.
-
(1992)
Immunol. Today
, vol.13
, pp. 271-276
-
-
Lynn, W.A.1
Golenbock, D.T.2
-
15
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock F.L., Hardiman G., Timans J.C., Kastelein R.A., Bazan J.F. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. U. S. A. 95:1998;588-593.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 588-593
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
16
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Huffel C.V.et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 282:1998;2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
-
17
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi S.T., Lariviere L., Leveque G., Clermont S., Moore K.J.et al. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:1999;615-625.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 615-625
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
-
18
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T.et al. Cutting edge: toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:1999;3749-3752.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
-
19
-
-
0034075754
-
The IL-1 receptor/toll-like receptor superfamily: Crucial receptors for inflammation and host defense
-
O'Neill L.A., Dinarello C.A. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol. Today. 21:2000;206-209.
-
(2000)
Immunol. Today
, vol.21
, pp. 206-209
-
-
O'Neill, L.A.1
Dinarello, C.A.2
-
20
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H., Henzel W.J., Shillinglaw W., Li S., Cao Z. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 7:1997;837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
21
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao Z., Henzel W.J., Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 271:1996;1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
22
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z., Xiong J., Takeuchi M., Kurama T., Goeddel D.V. TRAF6 is a signal transducer for interleukin-1. Nature. 383:1996;443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
23
-
-
0032526861
-
The human toll signaling pathway: Divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
-
Muzio M., Natoli G., Saccani S., Levrero M., Mantovani A. The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J. Exp. Med. 187:1998;2097-2101.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
24
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 11:1999;115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
25
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki N., Suzuki S., Duncan G.S., Millar D.G., Wada T.et al. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature. 416:2002;750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
-
26
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga M.A., Yeh W.C., Sarosi I., Duncan G.S., Furlonger C.et al. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1999;1015-1024.
-
(1999)
Genes Dev.
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
Duncan, G.S.4
Furlonger, C.5
-
27
-
-
0031774181
-
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
-
Kirschning C.J., Wesche H., Merrill Ayres T., Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J. Exp. Med. 188:1998;2091-2097.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2091-2097
-
-
Kirschning, C.J.1
Wesche, H.2
Merrill Ayres, T.3
Rothe, M.4
-
28
-
-
0028949390
-
RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family
-
Miyake K., Yamashita Y., Ogata M., Sudo T., Kimoto M. RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J. Immunol. 154:1995;3333-3340.
-
(1995)
J. Immunol.
, vol.154
, pp. 3333-3340
-
-
Miyake, K.1
Yamashita, Y.2
Ogata, M.3
Sudo, T.4
Kimoto, M.5
-
29
-
-
0032146713
-
Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression
-
Miyake K., Shimazu R., Kondo J., Niki T., Akashi S.et al. Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. J. Immunol. 161:1998;1348-1353.
-
(1998)
J. Immunol.
, vol.161
, pp. 1348-1353
-
-
Miyake, K.1
Shimazu, R.2
Kondo, J.3
Niki, T.4
Akashi, S.5
-
30
-
-
0028071612
-
Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: Unresponsiveness of X-linked immunodeficient B cells
-
Miyake K., Yamashita Y., Hitoshi Y., Takatsu K., Kimoto M. Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells. J. Exp. Med. 180:1994;1217-1224.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1217-1224
-
-
Miyake, K.1
Yamashita, Y.2
Hitoshi, Y.3
Takatsu, K.4
Kimoto, M.5
-
31
-
-
0025992101
-
Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein
-
Burk O., Klempnauer K.H. Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein. EMBO J. 10:1991;3713-3719.
-
(1991)
EMBO J.
, vol.10
, pp. 3713-3719
-
-
Burk, O.1
Klempnauer, K.H.2
-
32
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2
-
da Silva Correia J., Soldau K., Christen U., Tobias P.S., Ulevitch R.J. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2. J. Biol. Chem. 276:2001;21129-21135.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21129-21135
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
33
-
-
0035885127
-
N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharide
-
Ohnishi T., Muroi M., Tanamoto K. N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharide. J. Immunol. 167:2001;3354-3359.
-
(2001)
J. Immunol.
, vol.167
, pp. 3354-3359
-
-
Ohnishi, T.1
Muroi, M.2
Tanamoto, K.3
-
34
-
-
0035796406
-
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
-
Schromm A.B., Lien E., Henneke P., Chow J.C., Yoshimura A.et al. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J. Exp. Med. 194:2001;79-88.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 79-88
-
-
Schromm, A.B.1
Lien, E.2
Henneke, P.3
Chow, J.C.4
Yoshimura, A.5
-
35
-
-
0035834135
-
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4
-
Visintin A., Mazzoni A., Spitzer J.A., Segal D.M. Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc. Natl. Acad. Sci. U. S. A. 98:2001;12156-12161.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 12156-12161
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.A.3
Segal, D.M.4
-
36
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y., Akashi S., Nagafuku M., Ogata M., Iwakura Y.et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3:2002;667-672.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
-
37
-
-
0036493503
-
Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide
-
Nagai Y., Shimazu R., Ogata H., Akashi S., Sudo K.et al. Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. Blood. 99:2002;1699-1705.
-
(2002)
Blood
, vol.99
, pp. 1699-1705
-
-
Nagai, Y.1
Shimazu, R.2
Ogata, H.3
Akashi, S.4
Sudo, K.5
-
38
-
-
0032532315
-
RP105 is associated with MD-1 and transmits an activation signal in human B cells
-
Miura Y., Shimazu R., Miyake K., Akashi S., Ogata H.et al. RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood. 92:1998;2815-2822.
-
(1998)
Blood
, vol.92
, pp. 2815-2822
-
-
Miura, Y.1
Shimazu, R.2
Miyake, K.3
Akashi, S.4
Ogata, H.5
-
39
-
-
0034795208
-
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
-
Randow F., Seed B. Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability. Nat. Cell Biol. 3:2001;891-896.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 891-896
-
-
Randow, F.1
Seed, B.2
-
40
-
-
0037127309
-
MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
-
da Silva Correia J., Ulevitch R.J. MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor. J. Biol. Chem. 277:2002;1845-1854.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1845-1854
-
-
Da Silva Correia, J.1
Ulevitch, R.J.2
-
42
-
-
0036289969
-
Identification of LPS-binding peptide fragment of MD-2, a toll-receptor accessory protein
-
Mancek M., Pristovsek P., Jerala R. Identification of LPS-binding peptide fragment of MD-2, a toll-receptor accessory protein. Biochem. Biophys. Res. Commun. 292:2002;880-885.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.292
, pp. 880-885
-
-
Mancek, M.1
Pristovsek, P.2
Jerala, R.3
-
43
-
-
0030760314
-
Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution
-
Beamer L.J., Carroll S.F., Eisenberg D. Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution. Science. 276:1997;1861-1864.
-
(1997)
Science
, vol.276
, pp. 1861-1864
-
-
Beamer, L.J.1
Carroll, S.F.2
Eisenberg, D.3
-
44
-
-
0025319864
-
Shared actions of endotoxin and taxol on TNF receptors and TNF release
-
Ding A.H., Porteu F., Sanchez E., Nathan C.F. Shared actions of endotoxin and taxol on TNF receptors and TNF release. Science. 248:1990;370-372.
-
(1990)
Science
, vol.248
, pp. 370-372
-
-
Ding, A.H.1
Porteu, F.2
Sanchez, E.3
Nathan, C.F.4
-
45
-
-
0034723186
-
Mouse toll-like receptor 4·MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol
-
Kawasaki K., Akashi S., Shimazu R., Yoshida T., Miyake K.et al. Mouse toll-like receptor 4·MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol. J. Biol. Chem. 275:2000;2251-2254.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2251-2254
-
-
Kawasaki, K.1
Akashi, S.2
Shimazu, R.3
Yoshida, T.4
Miyake, K.5
-
46
-
-
0034746813
-
Cutting edge: Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharide mimetic action of taxol
-
Kawasaki K., Gomi K., Nishijima M. Cutting edge: Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharide mimetic action of taxol. J. Immunol. 166:2001;11-14.
-
(2001)
J. Immunol.
, vol.166
, pp. 11-14
-
-
Kawasaki, K.1
Gomi, K.2
Nishijima, M.3
-
47
-
-
0025193891
-
Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo
-
Kovach N.L., Yee E., Munford R.S., Raetz C.R., Harlan J.M. Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo. J. Exp. Med. 172:1990;77-84.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 77-84
-
-
Kovach, N.L.1
Yee, E.2
Munford, R.S.3
Raetz, C.R.4
Harlan, J.M.5
-
48
-
-
0035211130
-
Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition
-
Akashi S., Nagai Y., Ogata H., Oikawa M., Fukase K.et al. Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. Int. Immunol. 13:2001;1595-1599.
-
(2001)
Int. Immunol.
, vol.13
, pp. 1595-1599
-
-
Akashi, S.1
Nagai, Y.2
Ogata, H.3
Oikawa, M.4
Fukase, K.5
-
50
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien E., Means T.K., Heine H., Yoshimura A., Kusumoto S.et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J. Clin. Invest. 105:2000;497-504.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
-
51
-
-
0036222620
-
Human Toll-like receptor 4 recognizes host-specific LPS modifications
-
Hajjar A.M., Ernst R.K., Tsai J.H., Wilson C.B., Miller S.I. Human Toll-like receptor 4 recognizes host-specific LPS modifications. Nat. Immunol. 3:2002;354-359.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 354-359
-
-
Hajjar, A.M.1
Ernst, R.K.2
Tsai, J.H.3
Wilson, C.B.4
Miller, S.I.5
-
52
-
-
0036084367
-
MD-2, a novel accessory molecule, is involved in species-specific actions of salmonella lipid A
-
Muroi M., Ohnishi T., Tanamoto K. MD-2, a novel accessory molecule, is involved in species-specific actions of salmonella lipid A. Infect. Immun. 70:2002;3546-3550.
-
(2002)
Infect. Immun.
, vol.70
, pp. 3546-3550
-
-
Muroi, M.1
Ohnishi, T.2
Tanamoto, K.3
-
53
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones E.A., Popova L., Kwinn L., Haynes L.M., Jones L.P.et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1:2000;398-401.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
-
54
-
-
0034768425
-
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
-
Haynes L.M., Moore D.D., Kurt-Jones E.A., Finberg R.W., Anderson L.J.et al. Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus. J. Virol. 75:2001;10730-10737.
-
(2001)
J. Virol.
, vol.75
, pp. 10730-10737
-
-
Haynes, L.M.1
Moore, D.D.2
Kurt-Jones, E.A.3
Finberg, R.W.4
Anderson, L.J.5
-
56
-
-
0034834474
-
Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol
-
Kawasaki K., Akashi S., Shimazu R., Yoshida T., Miyake K.et al. Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol. J. Endotoxin Res. 7:2001;232-236.
-
(2001)
J. Endotoxin Res.
, vol.7
, pp. 232-236
-
-
Kawasaki, K.1
Akashi, S.2
Shimazu, R.3
Yoshida, T.4
Miyake, K.5
-
57
-
-
0037177833
-
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway
-
Vabulas R.M., Ahmad-Nejad P., Ghose S., Kirschning C.J., Issels R.D.et al. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J. Biol. Chem. 277:2002;15107-15112.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15107-15112
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Ghose, S.3
Kirschning, C.J.4
Issels, R.D.5
-
58
-
-
0037177825
-
Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
-
Asea A., Rehli M., Kabingu E., Boch J.A., Bare O.et al. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277:2002;15028-15034.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15028-15034
-
-
Asea, A.1
Rehli, M.2
Kabingu, E.3
Boch, J.A.4
Bare, O.5
-
59
-
-
0036467447
-
Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
-
Bulut Y., Faure E., Thomas L., Karahashi H., Michelsen K.S.et al. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J. Immunol. 168:2002;1435-1440.
-
(2002)
J. Immunol.
, vol.168
, pp. 1435-1440
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Karahashi, H.4
Michelsen, K.S.5
-
60
-
-
0035800883
-
Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation
-
Sasu S., LaVerda D., Qureshi N., Golenbock D.T., Beasley D. Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation. Circ. Res. 89:2001;244-250.
-
(2001)
Circ. Res.
, vol.89
, pp. 244-250
-
-
Sasu, S.1
LaVerda, D.2
Qureshi, N.3
Golenbock, D.T.4
Beasley, D.5
-
61
-
-
0035903158
-
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
-
Vabulas R.M., Ahmad-Nejad P., da Costa C., Miethke T., Kirschning C.J.et al. Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J. Biol. Chem. 276:2001;31332-31339.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31332-31339
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Da Costa, C.3
Miethke, T.4
Kirschning, C.J.5
-
62
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi K., Burkart V., Flohe S., Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 164:2000;558-561.
-
(2000)
J. Immunol.
, vol.164
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
63
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y., Watari M., Jerud E.S., Young D.W., Ishizaka S.T.et al. The extra domain A of fibronectin activates Toll-like receptor 4. J. Biol. Chem. 276:2001;10229-10233.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
-
64
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot L., Balloy V., McCormack F.X., Golenbock D.T., Chignard M.et al. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J. Immunol. 168:2002;5989-5992.
-
(2002)
J. Immunol.
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
-
65
-
-
0037189544
-
Monomeric recombinant MD-2 binds TLR4 tightly and confers LPS responsiveness
-
Re F., Strominger J.L. Monomeric recombinant MD-2 binds TLR4 tightly and confers LPS responsiveness. J. Biol. Chem. 277:2002;23427-23432.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23427-23432
-
-
Re, F.1
Strominger, J.L.2
-
66
-
-
0037080024
-
Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
-
Zarember K.A., Godowski P.J. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168:2002;554-561.
-
(2002)
J. Immunol.
, vol.168
, pp. 554-561
-
-
Zarember, K.A.1
Godowski, P.J.2
-
67
-
-
2642708378
-
The molecular mechanism of B cell activation by toll-like receptor protein RP-105
-
Chan V.W., Mecklenbrauker I., Su I., Texido G., Leitges M.et al. The molecular mechanism of B cell activation by toll-like receptor protein RP-105. J. Exp. Med. 188:1998;93-101.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 93-101
-
-
Chan, V.W.1
Mecklenbrauker, I.2
Su, I.3
Texido, G.4
Leitges, M.5
-
68
-
-
0032473405
-
B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells
-
Grumont R.J., Rourke I.J., O'Reilly L.A., Strasser A., Miyake K.et al. B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J. Exp. Med. 187:1998;663-674.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 663-674
-
-
Grumont, R.J.1
Rourke, I.J.2
O'Reilly, L.A.3
Strasser, A.4
Miyake, K.5
-
69
-
-
0034601022
-
The Toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells
-
Ogata H., Su I.-H., Miyake K., Nagai Y., Akashi S.et al. The Toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192:2000;23-30.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 23-30
-
-
Ogata, H.1
Su, I.-H.2
Miyake, K.3
Nagai, Y.4
Akashi, S.5
-
70
-
-
15144354771
-
Molecular cloning of human RP105
-
Fugier-Vivier I., de Bouteiller O., Guret C., Fossiez F., Banchereau J.et al. Molecular cloning of human RP105. Eur. J. Immunol. 27:1997;1824-1827.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1824-1827
-
-
Fugier-Vivier, I.1
De Bouteiller, O.2
Guret, C.3
Fossiez, F.4
Banchereau, J.5
-
71
-
-
0035869553
-
Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses
-
Means T.K., Jones B.W., Schromm A.B., Shurtleff B.A., Smith J.A.et al. Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses. J. Immunol. 166:2001;4074-4082.
-
(2001)
J. Immunol.
, vol.166
, pp. 4074-4082
-
-
Means, T.K.1
Jones, B.W.2
Schromm, A.B.3
Shurtleff, B.A.4
Smith, J.A.5
-
72
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee J.Y., Sohn K.H., Rhee S.H., Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 276:2001;16683-16689.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
73
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot L., Balloy V., McCormack F.X., Golenbock D.T., Chignard M.et al. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J. Immunol. 168:2002;5989-5992.
-
(2002)
J. Immunol.
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
|