Effect of K+ channel modulators on the antiallodynic effect of gabapentin

European Journal of Pharmacology

Volumn 484, Issue 2-3, 2004, Pages 201-208

  Mixcoatl Zecuatl, Teresa ^a   Medina Santillán, Roberto ^b   Reyes García, Gerardo ^b   Vidal Cantú, Guadalupe C ^a   Granados Soto, Vinicio ^a,c  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^c UNIVERSIDAD MICHOACANA DE SAN NICOLÁS DE HIDALGO   (Mexico)

Author keywords

Apamin; Charybdotoxin; Gabapentin; Glibenclamide; K+ channel; Pinacidil

Indexed keywords

ANTIALLODYNIC AGENT; ANTIPAIN; APAMIN; CHARYBDOTOXIN; GABAPENTIN; GLIBENCLAMIDE; MARGATOXIN; PINACIDIL; POTASSIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIALLODYNIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; FEMALE; NERVE LIGATION; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SPINAL ROOT; TOUCH;

EID: 1642464887     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.11.022     Document Type: Article

References (51)

1. + channels. Science. 247:1990;852-854.
2. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Methods. 53:1994;55-63.
3. Chapman V., Suzuki R., Chamarette H.L.C., Rygh L.J., Dickenson A.H. Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats. Pain. 75:1998;261-272.
4. Cheng J.-K., Lai Y.-J., Chen C.-C., Cheng C.-R., Chiou L.-C. Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a model of postoperative pain. Anesthesiology. 98:2003;1472-1479.
5. Chizh B.A., Scheede M., Schlutz H. Antinociception and (R, S)-a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo. Naunyn-Schmiedeberg's Arch. Pharmacol. 362:2000;197-200.
6. + channels of muscle cells - their properties, regulation, and functions. J. Bioenerg. Biomembranes. 23:1991;509-535.
7. +-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin. Neurosci. Lett. 280:2000;107-110.
8. + channels. Annu. Rev. Pharmacol. Toxicol. 33:1993;597-637.
9. Field M.J., Oles R.J., Lewis A.S., McCleary S., Hughes J., Singh L. Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents. Br. J. Pharmacol. 121:1997;1513-1522.
10. Field M.J., McCleary S., Hughes J., Singh L. Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat. Pain. 80:1999;391-398.
11. ATP channels. Naunyn-Schmiedeberg's Arch. Pharmacol. 363:2001;537-542.
12. Galeotti N., Ghelardini C., Bartolini A. Involvement of potassium channels in amitriptyline and clomipramine analgesia. Neuropharmacology. 40:2001;75-84.
13. Garcia-Calvo M., Leonard R.J., Novick J., Stevens S.P., Schmalhofer W., Kaczorowski G.J., Garcia M.L. Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels. J. Biol. Chem. 268:1993;18866-18874.
14. Gee N.S., Brown J.P., Dissanayake V.U.K., Offord J., Thurlow R., Woodruff G.N. The novel anticonvulsant drug, gabapentin (neurontin), binds to the α2δ subunit of a calcium channel. J. Biol. Chem. 271:1996;5768-5776.
15. Gillin S., Sorkin L.S. Gabapentin reverses the allodynia produced by the administration of anti-GD2 ganglioside, an immunotherapeutic drug. Anesth. Analg. 86:1998;111-116.
16. Götz F., Feuerstein T.J., Meyer D.K. Effects of gabapentin on release of γ-aminobutyric acid from slices of rat neostriatum. Drug Res. 43:1993;636-638.
17. Granados-Soto V., Torres-López J.E., Argüelles C.F., Ortiz M.I. The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels. Neuropharmacology. 43:2002;917-923.
18. Hunter J.C., Gogas K.I., Hedley L.R., Jacobson L.O., Kassotakis L., Thompson J., Fontana D.J. The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain. Eur. J. Pharmacol. 324:1997;153-160.
19. Hwang J.H., Yaksh T.L. Effect of subarachnoid gabapentin on tactile-evoked allodynia in a surgically induced neuropathic pain model in the rat. Reg. Anesth. 22:1997;249-256.
20. Ishikawa K., Tanaka M., Black J.A., Waxman S.G. Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy. Muscle Nerve. 22:1999;502-507.
21. Jun J.H., Yaksh T.L. Effect of intrathecal gabapentin and 3-isobutyl GABA on the hyperalgesia observed after thermal injury in the rat. Anesth. Analg. 86:1998;348-354.
22. Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 50:1992;355-363.
23. Kim S.D., Choi J.O., Rim H.D., Cho H.J. Downregulation of voltage-gated potassium channel α gene expression in dorsal root ganglia following chronic constriction injury of the rat sciatic nerve. Mol. Brain Res. 105:2002;146-152.
24. Loscher W., Honack D., Taylor C.P. Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain. Neurosci. Lett. 128:1991;150-154.
25. MacFarlane B.V., Wright A., O'Callaghan J., Benson H.A. Chronic neuropathic pain and its control by drugs. Pharmacol. Ther. 75:1997;1-19.
26. Malmberg A.B., Yaksh T.L. Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat. J. Pharmacol. Exp. Ther. 263:1992;136-146.
27. Mellick G.A., Mellicy L.B., Mellick L.B. Gabapentin in the management of reflex sympathetic dystrophy. J. Pain Symp. Manag. 10:1995;265-266.
28. Ng G.Y.K., Bertrand S., Sullivan R., Ethier N., Wang J., Yergey J., Belly M., Trimble L., Bateman K., Alder L., Smith A., McKernan R., Metter K., O'Neill G.P., Lacaille J.C., Hébert T.E. γ-Aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Mol. Pharmacol. 59:2001;144-152.
29. + channel blocker antagonizes morphine analgesia. Eur. J. Pharmacol. 186:1990;377-378.
30. + channels by diclofenac. Eur. J. Pharmacol. 438:2002;85-91.
31. + channels. Pharmacol. Biochem. Behav. 74:2003;465-470.
32. Ouadid-Ahidouch H., Coppenolle F.V., Bourhis X.L., Belhaj A., Prevarskaya N. Potassium channels in rat prostate epithelial cells. FEBS Lett. 459:1999;15-21.
33. Partridge B.J., Chaplan S.R., Sakamoto E., Yaksh T.L. Characterization of the effects of gabapentin and 3-isobutyl-γ-aminobutyric acid on substance P-induced thermal hyperalgesia. Anesthesiology. 88:1998;196-205.
34. B agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat. Pain. 90:2001;217-226.
35. Price M., Lee S.C., Deutsch C. Charybdotoxin inhibits proliferation and interleukin 2 production in human peripheral blood lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 86:1989;10171-10175.
36. Rasband M.N., Park E.W., Vanderah T.W., Lai J., Porreca F., Trimmer J.A. Distinct potassium channels on pain-sensing neurons. Proc. Natl. Acad. Sci. U. S. A. 98:2001;13373-13378.
37. Reimann W. Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action? Eur. J. Pharmacol. 94:1983;341-344.
38. Rice A.S.C., Maton S. Gabapentin in postherpetic neuralgia: a randomized, double-blind, placebo controlled study. Pain. 94:2001;215-224.
39. + channels. J. Physiol. 79:1984;259-264.
40. Shimoyama M., Shimoyama N., Hori Y. Gabapentin affects glutamatergic excitatory neurotransmission in the rat dorsal horn. Pain. 85:2000;405-414.
41. Singh L., Field M.J., Ferris P., Hunter J.C., Oles R.J., Williams R.G., Woodruff G.N. The antiepileptic agent gabapentin (neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine. Psychopharmacology. 127:1996;1-9.
42. Stefani A., Spadoni F., Giacomini P., Lavaroni F., Bernardi G. The effects of gabapentin on different ligand-and voltage-gated currents in isolated cortical neurons. Epilepsy Res. 43:2001;239-248.
43. Stretton D., Miura M., Bevisi M.G., Barnes P.J. Calcium-activated potassium channels mediate prejunctional inhibition of peripheral sensory nerves. Proc. Natl. Acad. Sci. U. S. A. 9:1992;1325-1329.
44. 3H]-gabapentin binding to a novel site in rat brain: homogenate binding studies. Eur. J. Pharmacol. 244:1993;293-301.
45. Taylor C.P., Gee N.S., Su T.Z., Kocsis J., Welty D., Brwon J.P., Dooley D.J., Boden P., Singh L. A summary of mechanistic hypothesis of gabapentin pharmacology. Epilepsy Res. 29:1998;233-249.
46. Vergoni A.V., Scarano A., Bertolini A. Pinacidil potentiates morphine analgesia. Life Sci. 50:1992;PL135-PL138.
47. Wallin J., Cui J.G., Yakhnitsa V., Schechtmann G., Meyerson B.A., Linderoth B. Gabapentin and pregabalin suppress tactile allodynia and potentiate spinal cord stimulation in a model of neuropathy. Eur. J. Pain. 6:2002;261-272.
48. Welch S.P., Dunlow L.D. Antinociceptive activity of intrathecally administered potassium channel openers and opioid agonists, a common mechanism of action? J. Pharmacol. Exp. Ther. 267:1993;390-399.
49. Yaksh T.L., Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol. Behav. 17:1976;1031-1036.
50. Zimmermann M. Ethical guidelines for investigations on experimental pain in conscious animals. Pain. 16:1983;109-110.
51. Zushida K., Onodera K., Kamei J. Effect of diabetes on pinacidil-induced antinociception in mice. Eur. J. Pharmacol. 453:2002;209-215.